Unlocking epigenetic activities with single-cell multi-omics technologies in Epigenome Technologies

San Diego, CA 92121
Joined July 2023
Epigenetics Update - Altered sperm DNA methylation provides an epigenetic route from overweight and older men to intergenerational disease transmission pnas.org/doi/full/10.1073/pn… Jacquetta Trasler & @KimminsSarah (@mcgillu) in PNAS #Epigenetics #DNAm --- epigenometech.com
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Epigenetics Update - Environmental chemical mixtures reprogram mammary epithelial development to epigenetic states associated with breast cancer pnas.org/doi/full/10.1073/pn… @KUPERWASSERLAB (@TuftsMedSchool) in PNAS #Epigenetics #Cancer #DNAm --- epigenometech.com
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Learn how we used Droplet Paired-Tag to assess RNA expression and histone mods in brain cells and PBMCs to identify novel cell-type-specific CREs and heritability factors linked to AD #Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics u.epigenome.us/I8R4vBn2
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Epigenetics Preprint - Dissection of Polycomb complexes reveals canonical PRC1-independent 3D chromatin interactions biorxiv.org/content/10.64898… @mileshuseyin & @Anders_S_Hansen (@MITdeptofBE) in bioRxiv #Epigenetics #Chromatin #PRC1 #Polycomb --- epigenometech.com
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Epigenetics Update - Molecular mechanism of residue-specific nucleosome acetylation cell.com/molecular-cell/full… Marisa Müller (@LMU_Muenchen) & Sebastian Eustermann (@embl) in @MolecularCell #Epigenetics #Nucleosomes #Chromatin #H4K16 --- epigenometech.com
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Learn how we used single-cell CUT&Tag and Droplet Paired-Tag to profile PBMCs, generating over 70,000 single-cell profiles and identifying vast numbers of cis-regulatory elements. #Epigenetics #SingleCell #DropletPairedTag #PairedTag #Multiomics u.epigenome.us/I8R4vBn2
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Epigenetics Update - Regulation of target gene expression by chromatin-associated protein-coding transcripts in plants science.org/doi/10.1126/scie… Lu Han/Yuxiang Yuan & Yijun Qi (@Tsinghua_Uni) in @ScienceMagazine #Epigenetics #Chromatin #Plants --- epigenometech.com
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Epigenetics Update - Single-cell CRISPR screen maps epigenetic regulators of lineage specification and malignancies in human HSPCs cell.com/cell-stem-cell/full… #Epigenetics #Chromatin #CRISPR #StemCells #HSPCs --- Cancer, immunology, and aging; epigenometech.com
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Epigenome Technologies Inc. retweeted
Congratulations to NYGC CEO & Scientific Director Bing Ren, PhD, elected to the @theNAMedicine! His pioneering work in epigenomics has transformed our understanding of how genome organization and gene regulation shape cellular function and disease. nygenome.org/news-events/new…
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New Epigenome Technologies Blog! epigenometech.com/blog/posts… "A New Multi-omic Epigenetic Study Describes Human Adult Hippocampal Aging at the Single-Cell Level" #Epigenetics #Chromatin #SingleCell #Aging #MultiOmics #BrainAging #DNAm #ChromatinAccessibility
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Epigenetics Update - Brain DNA methylation, APOE genotype and Alzheimer's disease neuropathology in a large postmortem cohort nature.com/articles/s43587-0… Guanhong Miao & Jinying Zhao (@USouthFlorida) in @NatureAging #Epigenetics #DNAm #APOE #Alzheimers --- epigenometech.com
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Epigenetics Update - SUMO2 deletion changes chromatin accessibility and enhances cytotoxic T cell activation and tumor infiltration science.org/doi/10.1126/scia… Yuan Chen (@UCSDMedSchool) in @ScienceAdvances #Epigenetics #SUMO2 #Chromatin --- epigenometech.com
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Epigenome Technologies offers an end-to-end Single-Cell Paired-Tag service, the first multiomic assay that simultaneously captures RNA expression and epigenetic marks from preparation to data analysis #Epigenetics #SingleCell #PairedTag #Multiomics u.epigenome.us/vyZjktjA
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Epigenetics Update - Long-term immunoprophylaxis by TLR9 ligand mediates macrophage-ILC cross-talk against respiratory viral infection science.org/doi/10.1126/scia… #Epigenetics #Chromatin #ViralInfections --- High-resolution insights without cell sorting; epigenometech.com
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Epigenetics Update - Epigenetic insights into extreme longevity in the world's oldest terrestrial animal, Jonathan science.org/doi/10.1126/scia… Stephen W. Clark (Kallel Foundation) in Sci Adv #Epigenetics #Aging #DNAm #Jonathan --- epigenometech.com
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New from Epigenome Technologies: Paired-Tag - the first single-cell multiomic assay that simultaneously captures RNA expression and epigenetic marks #Epigenetics #SingleCell #PairedTag #Multiomics Find out more at: u.epigenome.us/pCTHvQHK
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Epigenetics Update - Epigenetic aging and transposon dysregulation reflect size-related lifespan compression in dogs science.org/doi/10.1126/scie… @blaisemariner /Brianah McCoy & @SMack_Lab (@ASU) in @Science #Epigenetics #Aging #Dogs --- epigenometech.com
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