GCAR is a 501(c)(3) non-profit corporation pioneering collaborative, innovative clinical trials to speed the discovery and development of cures
Larkspur, CA
Joined October 2017
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Global Coalition for Adaptive Research retweeted
We’re thankful to partner with @GCAResearch in support of #GBMDay.
Through this collaboration, we aim to continue providing better access to treatments and advancements in glioblastoma research.
Learn how you can take action at: BrainTumor.org/GBMDay
Global Coalition for Adaptive Research retweeted
The newly seated Project Cure CRC Consortium, assembled to guide the Alliance's work toward cures, got its first look at KLEOS at the ASCO annual meeting in Chicago. The Alliance's adaptive clinical trial platform was the focus of a panel featuring Alliance CEO Michael Sapienza and Dr. Meredith Buxton, CEO of the Global Coalition for Adaptive Research, among other oncology leaders. Panelists discussed KLEOS's vast potential and urgent goal to bring new treatments to patients faster.
Learn more about KLEOS: bit.ly/KLEOS-Announcement
#ASCO26 @ASCO
Global Coalition for Adaptive Research retweeted
#Cholangiocarcinoma Awareness Month is here! 💚 Honor our 20th Anniversary by sharing knowledge & stories. Download social media graphics to help tell YOUR story and spread the word: cholangiocarcinoma.org/aware…
Global Coalition for Adaptive Research retweeted
Clinical trial eligibility often depends on factors like #braintumor type, overall health, and results from biomarker testing.
Join our #MyTumorID webinar on Oct. 24 to learn more about how clinical trials work. 🔗
Save your spot today: braintumor.org/brain-tumors/…
Global Coalition for Adaptive Research retweeted
Good looking bunch! GBM AGILE has exciting new therapies in the pipeline and is rapidly becoming a repository of massive amounts of data with plans for extensive molecular profiling and translational work. Kudos to the @GCAResearch team!
GBM AGILE leadership gathering at #ASCO2025
Trial leadership met to discuss new trial innovations and to advance exciting plans to maximize learning from every patient 🧬🔎
Since launching in 2019, seven investigational therapies have entered the trial, and sites in six countries on three continents have screened over 2300 patients. 🌏
Thank you trial leadership for your dedication to accelerating the discovery, evaluation, and development of new treatment options for patients with #glioblastoma. 🧠
We are #FasterTogether! 🙌
#GBMAGILE
Global Coalition for Adaptive Research retweeted
🧵 Congratulations to @GCAResearch on IMPACT PDAC (Innovative Master Protocol to Accelerate Clinical Therapeutics for Pancreatic Ductal Adenocarcinoma), the next phase in a groundbreaking effort to advance new treatments for #pancreaticcancer.
We’re thrilled to unveil the official trial name and logo of GCAR’s forthcoming pancreatic cancer clinical trial! 📣
IMPACT PDAC - Innovative Master Protocol to Accelerate Clinical Therapeutics for Pancreatic Ductal Adenocarcinoma is an investigator-driven, patient-centric effort to support clinical development of new treatment options for metastatic #PancreaticCancer #PDAC.
This effort will continue to accelerate research to address the urgent need for new and more effective therapies for pancreatic cancer patients. 💊⚡️
To learn more about the forthcoming IMPACT PDAC master protocol, visit:
gcaresearch.org/research/imp…
Global Coalition for Adaptive Research retweeted
Congratulations @GCAResearch on this exciting milestone! This effort marks a significant step forward in accelerating research and bringing urgently needed, more effective therapies to pancreatic cancer patients. 💜
Global Coalition for Adaptive Research retweeted
This #GrayMay, share info about #braintumors.
More than 1 million Americans are living with a brain tumor. ~73% of brain tumors are benign & ~27% are malignant.
Reshare these impactful stats and inspire others to take action this #BTAM at: BrainTumor.org/BTAM
Global Coalition for Adaptive Research retweeted
Today, we kick off #BrainTumorAwarenessMonth – a time to come together to support, empower, and amplify the voice of the #braintumor community.
Learn how you can #GoGrayInMay at BrainTumor.org/BTAM 🩶
#BTAM #GrayMay
Global Coalition for Adaptive Research retweeted
Wonderful summary of the global effort to defeat GBM @GCAResearch (and I couldn’t go more #GrayMay if I tried:-)
In honor of Brain Tumor Awareness Month, we are excited to provide an update on the progress of GBM AGILE, an innovative clinical trial for patients with newly diagnosed and recurrent #glioblastoma 🧠
To learn more about this trial, visit: gcaresearch.org/research/gbm…
#GrayMay #GoGrayInMay #BrainTumorAwarenessMonth #GBMAGILE
Global Coalition for Adaptive Research retweeted
In the competitive arena of clinical trials, sponsors often guard their drugs closely, navigating the complex approval path.
Dr. Meredith Buxton describes how at Global Coalition for Adaptive Research (GCAR), they’ve developed systems aimed at reducing trial costs by leveraging shared resources, validating the efficiency of adaptive trials.
Tune in now: berryconsultants.com/resourc…
Global Coalition for Adaptive Research retweeted
With no suitable home for innovative trials, GCAR (Global Coalition for Adaptive Research) emerged as an independent nonprofit to sponsor and disseminate the findings from groundbreaking studies like GBM AGILE.
Dr. Meredith Buxton describes how GCAR acts as an honest broker—uniting clinicians, patients, advocacy groups, and industry partners to push the envelope in adaptive research.
Tune in to the full episode at: berryconsultants.com/resourc…
Global Coalition for Adaptive Research retweeted
Dr Meredith Buxton explains how master protocols are revolutionizing clinical trials by creating efficient frameworks to test multiple investigational agents simultaneously.
The I-SPY program introduced one of the first such innovations by designing a reusable platform, thereby accelerating timelines and enhancing the evaluation of drugs to pave the way for modern adaptive trials.
Listen to the full podcast episode, "I-SPY 2 to GBM AGILE and Beyond" at: berryconsultants.com/resourc…
Global Coalition for Adaptive Research retweeted
We are proud to unveil the official name and logo for an exciting new clinical trial designed specifically for patients with biliary tract cancer!
In partnership with GCAR (the Global Coalition for Adaptive Research), the Cholangiocarcinoma Foundation (CCF) is helping to lead the way in creating a patient-focused, cutting-edge clinical trial called ARBOR BTC.
A.R.B.O.R. BTC — Advancing Research and Breakthroughs for Oncology Regimens in Biliary Tract Cancer — is an investigator-driven, patient-centric effort dedicated to accelerating the development of new treatment options for those facing biliary tract cancers, including cholangiocarcinoma.
Now, more than ever, this work is critical. With increasing challenges and uncertainty around federal research funding, innovative collaborations like ARBOR BTC are essential to driving progress, offering hope, and expanding options for patients and their families.
Learn more about the ARBOR BTC master protocol here:
Global Coalition for Adaptive Research retweeted
It’s a privilege to partner with @GCAResearch. Together, we continue to make strides in advancing clinical research and care for #pancreaticcancer.
We're pleased to continue our partnership with the Global Coalition for Adaptive Research (@GCAResearch) in advancing the next steps for the former PanCAN Precision Promise platform for #pancreaticcancer. Check out the latest white papers from GCAR on revolutionizing and operationalizing adaptive platform clinical trials. ⬇️
Global Coalition for Adaptive Research retweeted
We're pleased to continue our partnership with the Global Coalition for Adaptive Research (@GCAResearch) in advancing the next steps for the former PanCAN Precision Promise platform for #pancreaticcancer. Check out the latest white papers from GCAR on revolutionizing and operationalizing adaptive platform clinical trials. ⬇️
We're thrilled to share valuable insights and actionable solutions with our latest white papers! 📄✨
Our first two papers dive into master protocols, highlighting benefits to stakeholders and key operational considerations for these specialized trials.
Stay tuned – we’ll be releasing more white papers in the coming months, covering topics like site activation & engagement, data management, financial efficiency, and resourcing.
We are eager to continue to educate and raise awareness about these innovative clinical trial solutions, with the goal of elevating and engaging the broader community.
We are #FasterTogether!
To read our latest white papers, visit: gcaresearch.org/educational-…
#ClinicalTrials #MasterProtocols #Innovation #WhitePapers #ClinicalResearch
Global Coalition for Adaptive Research retweeted
#DYK that #PDAC is the most common form of #PancreaticCancer, accounting for ~90% of all US pancreatic cancers cases? We're collaborating with @GCAResearch, @AIO_Onkologie & @PanCAN to further investigate our lead candidate in pancreatic cancer. More here: bit.ly/3QiRWdj
Global Coalition for Adaptive Research retweeted
This month’s FACTS Software webinar will be on Friday, February 28 at 11AM EST on the topic, “Can clinical trial simulation really improve the strategic decision making in drug development?”
The discussion will be hosted by Dr. Michael Krams who recently joined Berry Consultants after a career in drug development at Pfizer, Wyeth, and Janssen. He will be in conversation with past colleagues of his, Professor Andy Grieve and Dr. Tobia Mielke, as well as Dr. Kert Viele of Berry Consultants. They will share case studies and personal experiences on the significant role that statisticians can play in the strategic decision making process through clinical trial simulation. A topic you won’t want to miss!
To join this insightful session (free and open to the public), please register in advance at the following Zoom link: us02web.zoom.us/webinar/regi…
Global Coalition for Adaptive Research retweeted
I had the opportunity to attend @ASCO #GI25 and connect with experts advancing GI oncology. Check out key #pancreaticcancer research updates. 🔬 pancan.org/news/research-spo…
Learn the latest from @PanCAN Precision Promise, @Perthera’s PDACai v2.0, @GCAResearch, and more!
Global Coalition for Adaptive Research retweeted
Clinical trials are important for the #cholangiocarcinoma community because they drive progress in understanding and treating this rare and complex cancer. Here’s why they matter:
1️⃣ Advancing Treatment Options: With limited approved therapies for cholangiocarcinoma, clinical trials offer opportunities to develop and evaluate innovative treatments, such as targeted therapies, immunotherapies, and combination approaches.
2️⃣ Improving Patient Outcomes: Trials provide access to cutting-edge treatments that may improve survival rates, manage symptoms, and enhance patients' quality of life.
3️⃣ Personalized Medicine: Many trials focus on identifying biomarkers, paving the way for personalized treatment plans tailored to individual patients.
4️⃣ Contributing to Research: Every trial helps expand knowledge about cholangiocarcinoma, guiding future research and discoveries.
5️⃣ Offering Hope: For patients with limited options, clinical trials can provide hope by offering potential new paths when standard treatments are not effective.
By participating in or supporting clinical trials, the cholangiocarcinoma community helps shape the future of cancer care, bringing us closer to a cure.
Learn more at curecca.link/newlydx.
