We used hydrogen sulfide to rescue cells from ferroptosis, an important stress mechanism. Spearheaded by graduate student @SimranGupta2312; Wonderful collaboration with @Dharma_IITK
@kamatsid @iiserpune @tohoku_univ @angew_chem onlinelibrary.wiley.com/doi/…
@ANRFIndia
We find that the small molecules developed by us protect cells from this damage. Since ferroptosis is a key mechanism involved in several degenerative diseases, being able to protect cells is useful.
Harinath Chakrapani retweeted
38 year old Federer beat Nadal in the semis and outplayed Djokovic in the finals with two match points and gets clowned
38 year old Djokovic gets praised for being outplayed by both inferior Sinner and inferior Alcaraz
Federer was always held to far higher standards
Harinath Chakrapani retweeted
Players aren't allowed medical time outs for cramping
Another asterisk title in tennis.
Carlos earned $2,150,000 by going to the final, money that would've potentially gone to Zverev had he retired from cramps.
He's such a likable person but not above cheating or theft.
imo
Harinath Chakrapani retweeted
Alcaraz already has 7 majors. So yeah, it's possible he ends up chasing Novak’s numbers.
But you can’t undo what Djokovic did.
GOAT status is more than titles and records. It’s how the sport changed because of you.
Djoker broke the game, rebuilt it, and forced everyone else to evolve. With Federer and Nadal to battle.
Carlos gets to play in the world Novak created. And now he can take that game and do whatever he wants with it.
Excited to see where he takes it.
When the difference among these guys is 2-3%, any advantage can be capitalized! The illegal medical timeout given to the bully Crampcaraz is yet another example of how the organizers favor the big players. Not the first time, and not be the last time. Leaves a bad taste for fans
Zverev had some heated words with the supervisor in German while Carlos Alcaraz is being treated by the physio.
Zverev was ready to serve when the changeover ended, but Carlos’ treatment continued.
He appeared very angry that Carlos was able to take a medical time out for the cramps.
John McEnroe: “I don’t speak German Patrick but I’m willing to bet he’s saying, ‘Look he’s cramping. He doesn’t have an injury.’
Harinath Chakrapani retweeted
Announcing the next Pune Knowledge on Tap Event: on Thursday, 8th January, with Rashi Jain and Yogesh Wadadekar, on "Discovery of the Alaknanda Galaxy"
*Abstract*: Rashi and Yogesh's recent discovery of the Alaknanda Galaxy has the potential to shake up science's understanding of how early galaxies were formed after the Big Bang. Join us to understand how Alaknanda was discovered and what makes it special
*About the Speakers*: *_Rashi Jain_* is a senior research scholar at the National Centre for Radio Astrophysics – Tata Institute of Fundamental Research, Pune. She completed her B.Tech in metallurgical engineering from IIT BHU in 2020. In January 2021, she joined NCRA as an Integrated PhD student, where she completed her physics coursework in her first year. She is working on galaxy formation and evolution as part of her PhD thesis under the supervision of Prof. Yogesh Wadadekar. Her research interests involve the study of high-redshift galaxies to understand the origin of different galaxy morphologies that we see in the nearby universe. For this purpose, she uses multi-wavelength data from several advanced space-based telescopes to derive accurate properties of galaxies. She has also worked on galaxy clusters by imaging galaxy clusters using radio data from the Giant Metrewave Radio Telescope (GMRT). She is actively involved in public outreach activities (e.g., organising amateur stargazing sessions for general public) at NCRA.
*_Yogesh Wadadekar_*, is an astronomer and Professor at the National Centre for Radio
Astrophysics (NCRA) of the Tata Institute of Fundamental Research, Pune.
Professor Wadadekar completed his B.Tech from IIT Mumbai (1994), followed by M.Sc. and Ph.D. in Physics from IUCAA, Pune. His doctoral thesis earned him the prestigious Best PhD Thesis Award from the Indian Physics Association in 2000. His international experience includes six years of postdoctoral research in France and the USA, including serving as a Astronomical Software Scientist for the Sloan Digital Sky Survey at Princeton University. He joined the National Centre for Radio Astrophysics as a faculty member in 2007.
Professor Wadadekar's research encompasses galaxy evolution, large-area sky surveys, and active galactic nuclei, with particular expertise in machine learning applications to astrophysics. He has co- authored over 100 publications that have been cited more than 9000 times. His research group has achieved significant breakthroughs in multiwavelength studies of galaxy evolution using telescopes from space and from the ground.
He leads the development of India's software contributions to the Square Kilometer Array observatory (SKAO), including plans for India's SKA regional centre, an Exascale data processing centre to be built in India. His work in AI focuses on deep learning techniques for galaxy property prediction and developing computational frameworks for handling massive telescope data volumes.
His vision extends beyond traditional research, to graduate level teaching and public outreach. His teaching portfolio includes a very popular online course on Astronomical data analysis using Python.
*_Other details_*
*Timing:*
- 6:30pm: Registration, Mingling, Ordering
- 7:00pm: Topic Warmup and Quiz
- 7:15pm: Main Talk
- 8:30pm: Main event ends, but feel free to stick around afterwards to mingle, interact with the speaker or us, and have dinner.
*Parking:* There is parking in the basement (level -2) of the building—but be careful, big cars might not be able to navigate the turn. It is self-parking, you can park anywhere, but please do it mindfully, and don't park in such a way as to eat up multiple spots. You can also find parking on the street, either on the main ITI road or the bylanes.
*Payment:* ₹300 per person will be collected at the entrance, which can be applied towards your bill. (No, you don't have to drink beer or any other alcohol!)
*No Age Restriction:* There is no age restriction. You can bring children along.
Register here: luma.com/8g3x2nw4?utm_source…
England should drop most of their batters and play the next test with 8-9 bowlers. The bowlers anyway do the bulk of the batting as well
Congratulations Vartika @vartikajohn on the best poster award!
Lovely to be part of the ChemSci2025: Leaders in The Field symposium @IISERPune. Nice forum to discuss our lab's research @ChemicalScience. Thanks to Royal Society of Chemistry for the invitation
Lovely to be part of the ChemSci2025: Leaders in The Field symposium @IISERPune. Nice forum to discuss our lab's research @ChemicalScience. Thanks to Royal Society of Chemistry for the invitation
Nice to be a part of the symposium on AMR @csir_ncl. Excellent initiative to get clinicians, public policy experts, and researchers on one platform @IISERPune
Thanks to @RPrasad12 for featuring the paper in Science Chronicle sciencechronicle.in/2025/12/…
Pleased to see the coverage in Prabhat प्रभात, Marathi newspaper. @csir_ncl @IISERPune
Pleased to see the coverage in Prabhat प्रभात, Marathi newspaper. @csir_ncl @IISERPune
We developed a prodrug to address phenotypic AMR in Mycobacterium tuberculosis pubs.acs.org/doi/full/10.102…. A nice collaboration with Amit Singh @iiscbangalore Jen Hirschi, Binghamton University, Sid Chopra @CSIR_CDRI and Chetan Gadgil, @csir_ncl @IISERPune @Anand_Kumar_T
We developed a prodrug to address phenotypic AMR in Mycobacterium tuberculosis pubs.acs.org/doi/full/10.102…. A nice collaboration with Amit Singh @iiscbangalore Jen Hirschi, Binghamton University, Sid Chopra @CSIR_CDRI and Chetan Gadgil, @csir_ncl @IISERPune @Anand_Kumar_T
Published in Journal of Medicinal Chemistry, we report a prodrug of Moxifloxacin (MXF), a frontline anti-bacterial. The prodrug had comparable efficacy to MXF in replicating Mtb and significantly enhanced lethality in nonreplicating Mtb, the causative agent of tuberculosis.
Thanks to the patience and perseverance from Anand, @Anand_Kumar_T a former graduate student from our lab! Funding by @dbtIndia, @iiserpune, @IndiaDST, Ignite Life Sciences @ignitelsf , @CSIR_IND and NSF, USA is gratefully acknowledged.
Harinath Chakrapani retweeted
#Leprosy may be “eliminated” on paper, but for #India’s #ScheduledTribes, it remains a lived reality. Though just 8.6% of the population, they now account for 20% of new cases. A system that promised to end leprosy is failing its most vulnerable. @oommen writes: or-f.org/35650

















