We study the microbiome and its effect on intestinal immunity
Stanford University
Joined March 2020
- Tweets72
- Following130
- Followers406
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Howitt Lab retweeted
Our work deorphanizing MCT6 as the missing gut Lac-Phe transporter is out today @CellCellPress: local gut lactate metabolism influences gut-brain crosstalk, and also explains metformin’s effects on body weight. Congratulations to @Shuke_Xiao @alanshtung!
cell.com/cell/fulltext/S0092…
Excited to share our work in Science Immunology! Tuft cell signaling remodels the follicle-associated epithelium, influences M cell maturation, and promotes antigen-specific IgA responses. Led by @gabebarron. Thanks @DrRosenIBD & @jakob_moltke!
science.org/doi/10.1126/scii…
Howitt Lab retweeted
Not the first and likely not the last review on tuft cells. But for sure the most recent one, published in @NatRevGastroHep: Kalle and @XiaogangFeng did a great job summarizing recent findings related to tuft cells nature.com/articles/s41575-0… full-text access: rdcu.be/dVaOi
Congrats Miles on a great talk at FASEB Gastrointestinal Tract XXI. It was our labs first time at this meeting and sure we will be back. #GTSRC24
Howitt Lab retweeted
Online now: Distinct epigenomic landscapes underlie tissue-specific memory T cell differentiation dlvr.it/T9wX6X
Congratulations Eli! Everyone in the Howitt lab is so excited for you. U Chicago is getting an amazing scientist and colleague.
Howitt Lab retweeted
Please join us in welcoming our newest faculty member to the University of Chicago Department of Microbiology, Dr. Elias Roth Gerrick @GerrickElias, who will join as Assistant Professor effective September 1, 2024. (1/3)
Howitt Lab retweeted
Online now: Tuft cell acetylcholine is released into the gut lumen to promote anti-helminth immunity dlvr.it/T6qpgG
We're looking for a Research Associate/Technician to join our lab studying microbiome-immune interactions in the gut. We are open to recent college graduates and/or applicants expecting to graduate soon. Previous research experience is helpful, but not required.
Beautiful image. I would suspect they're "intermediate cells". We saw them with commensal protist colonization and others have seen with helminth infection. It would be cool to figure out what they do or if they can transition into more canonical Paneth or goblet cells
Howitt Lab retweeted
Very excited to share our paper led by @madisonstrine Intestinal tuft cell immune privilege enables norovirus persistence | Science Immunology science.org/doi/10.1126/scii… 1/n
If you’re interested in host-microbiota interactions but like your microbes with membrane bound organelles then our paper on symbiotic protists is for you @CellCellPress . Congrats @GerrickElias and a huge thank you to all our collaborators! cell.com/cell/fulltext/S0092…
Howitt Lab retweeted
💥Tenure-Track Faculty Job Alert!💥
Monell has an OPEN SEARCH for MULTIPLE positions (all levels)
If you study feeding behavior, metabolism, nutrition, olfaction, taste, chemesthesis, stem cells, or other topic in chemosensory biology, apply! 1/
apply.interfolio.com/79129
I hadn't thought much about the reptile microbiome before but @GerrickElias curiosity and pet tortoise inspired this story on intestinal protists in wild and domestic reptiles. Big thanks to our collaborators Tim @maddreptiles and Freeland @calacademy
journals.asm.org/doi/10.1128…
Howitt Lab retweeted
Announcing the 2023 Stanford Immunology Preview event! If you’re interested in applying to our PhD program, you’re invited to this virtual event. You’ll hear from our amazing faculty and students about what makes our scientific community so vibrant. bit.ly/stanfordimmpreview23
Why do intestinal tuft cells sense succinate when it doesn’t appear to help them clear parasites? Our collab with the Salzman lab at MCW sheds some light on this question. Congrats Connie, Lisa, and Gabe @gabebarron for all your great work! @PNASNews
pnas.org/doi/10.1073/pnas.22…
