J Curve Capital retweeted
He was famous for advocating for peace between Muslims and Christians. Islamists murdered him for that.
You don’t hate the BBC enough.
J Curve Capital retweeted
Be a hotel chain.
> Notice check-in takes four minutes
> Spend millions rolling out mobile check-in to get it under a minute
> Shorter lines. Lower payroll. Everyone celebrates
> Six months later, room upgrades and spa bookings are down
> Hire a consulting firm to "reimagine the guest journey"
> Spend another few million
> Consultants recommend a personalized welcome experience where staff talk to guests, learn their preferences and offer relevant upgrades
> Roll out the new initiative
> Check-in now takes four minutes
Everyone celebrates.
J Curve Capital retweeted
this might be my last normal tweet before biotech goes vertical
i'm not a whistleblower. I don't work at Lilly, Novo or any of the big labs
but there is a massive shift happening in human biology right now.
it's sitting in press releases and almost nobody reads them
the last 6 months alone:
- a once-daily pill roughly doubled median survival in metastatic pancreatic cancer (13.2 vs 6.6 months)
- a one-time gene editing infusion cut hereditary angioedema attacks 87%, and 62% of patients stayed attack-free and off all other prevention for 6 months
- a one-time gene edit for cholesterol dropped LDL up to 62%, and it held for over a year
- a personalized mrna vaccine beat keytruda alone in a 1,137 patient melanoma phase 3
- retatrutide hit ~28% weight loss in a phase 3
- an ai-designed drug entered phase 3
- a pill that regrows hair passed its second phase 3
- an immunotherapy that could let some rectal cancer patients skip surgery, chemo and radiation just got fda approved
- a man lived 271 days off dialysis on a pig kidney
- human cells were caught passing chromosome-sized chunks of DNA to their neighbors, and it changes how the neighbors behave
we are on the verge of an era where the human body is a software problem and the update cycle gets shorter everyday
stick around, it's going to get weird
bio/acc
J Curve Capital retweeted
Michael Pollan reveals how the introduction of caffeine completely changed human history and consciousness.
"Before caffeine, it was a very different world and a very different consciousness. People were drunk a lot of the time, buzzed almost all of the time because it was safer than water"
"Water was really how you got diseases. If you fermented things, even low alcohol, it killed a lot of the microbes. So people, even kids, drank hard cider for breakfast"
"Tea, chocolate, and coffee all arrive in the same decade in England, and things start to change... no one ate or drank boiling water or hot beverages before"
"Boiling it made it much safer. This gave this incredible public health boost to these places, and then you have the drug that fosters a kind of more linear, rational, focused way of thinking"
"People in the 1600s started writing about it saying, 'Wow, we have this new civil and sober drink that we can use.' And that, I think, makes possible things like the Industrial Revolution"
Readers added context they thought people might want to know
The clip repeats the myth that pre-caffeine people were mostly drunk because water was unsafe. Historians and medieval sources show water was commonly drunk from wells/springs while weak ale provided nutrition/calories, not a substitute for bad water.
leslefts.blogspot.com/2013/11/the-gr…
slate.com/human-interest…
fakehistoryhunter.net/2026/02/02/dri…
J Curve Capital retweeted
I was expecting Israel to be a little America—mostly English-speaking, a land full of convenience.
What I found was distinctly Middle Eastern—the people are brash, speak with their hands, and often don't know a lick of English. There are stray cats everywhere, mopeds, and graffiti. The street signs are in Hebrew, English, and Arabic. There is a mosque on prime beachfront property in Tel Aviv.
There is every kind of citizen imaginable. I saw Ethiopian Jews serving in the IDF. While touring an ancient Jewish site, I ran into a group of Arab schoolchildren also there to learn. I met a Mizrahi cab driver whose parents fled Morocco in the 50s.
Douglas Murray famously made Americans irate when he flamed Dave Smith on an episode of Joe Rogan for having never traveled to Israel—but he’s right. Visiting Israel shows you just how wrong the west is about the Jewish state.
Just go there.
American midterms are next week and I'm not allowed to vote in them despite visiting on business. Apartheid
J Curve Capital retweeted
Socialists be like: “I can’t manage my own life but you should trust me with the whole economy.”
J Curve Capital retweeted
They called it apartheid. The ballot box called them liars. Arab and Muslim parties are winning 17 seats in Israel’s parliament, the Knesset. Arab turnout was above 70% in town after town. Wait, I thought Zionists were racist, so how come these “racists” are giving parliamentary seats to Arabs and Muslims, who, in turn, came out to vote? Some villages hit 90% turnout.
They democratically participated and voted in a Zionist democratic system they believe in?
Arabs now hold about 14% of Israel’s parliament. Muslim MPs hold about 4% of Britain’s. Odd kind of apartheid, where the “oppressed” vote harder than London does.
J Curve Capital retweeted
In laymans terms,
Titanium implants are strong and the body accepts them, but they’re way too stiff
because the metal takes almost all the pressure, the real bone next to it gets lazy and starts to weaken over time (like a muscle that doesn’t get used).
This was the issue with earlier titanium implants and joint replacements
the new implant though are made from a special zinc alloy shaped like a lightweight, sponge-like lattice
it is flexible and almost like real bone, so it shares the load properly and doesn’t cause that weakening problem
Whats REALLY fucking cool is that its also designed to dissolve over time
So its a temporary implant, and as it dissolves, it releases minerals and ions that actually promote your new, healthy bone in its place
When the job is done, the implant is mostly gone and your own bone has taken over and is the proper strength
-medical engineering is a marvel
today while talkin to my friend (who’s a doctor) I learned something really crazy
That the titanium implants don't just sit in bone they actually bone grows into them
the oxide layer on titanium surface is chemically close enough to biological tissue that cells can't find the boundary so they erase it
osseointegration isn't the implant holding on it's biology deciding the metal belongs there
the skeleton adopts the foreign object as its own
Cyborg vibes
Friends in SA have been drinking the tap water all their lives and all got sick this week, so I googled the South African minister of water and sanitation.
What makes people think "yes. they've broken over 100 departments and institutions but I'm sure the water is fine"?
J Curve Capital retweeted
500 Milhões de Europeus, esperam que 300 Milhões de Americanos os protejam contra 120 Milhões de Russos que nem conseguem derrotar 40 Milhões de Ucranianos enquanto, não percebem, que estão a ser invadidos por 2000 milhões de Muçulmanos que se dizem perseguidos por 9 milhões de Israelitas!
J Curve Capital retweeted
“The US should intentionally cripple its space capabilities and try to bankrupt its leading launch company on purpose”
J Curve Capital retweeted
Crazy we thought this shit was over when the Wall fell.
Turns out Communism is a lot like herpes; you can’t cure it, you can only treat the flare ups.
J Curve Capital retweeted
Im trying to understand why Brazils largest laser hair removal company is down 30% today
Has the Brazilian bikini wax gone out of style?
Has the hair stopped growing?
Is Lula bringing back the bush?
These are the important questions Brazilian investors should be asking today
J Curve Capital retweeted
The thing I respect about China is that if they found out a "religious" group was talking about conquering them in their own country and murdering them for their race they would deal with it the same day.
J Curve Capital retweeted
Germans are like children. Literally nothing is ever their responsibilty or fault. Blame the USA, blame Russia, blame anyone but themselves for literally everything that goes wrong. Decades spent creating the most anti-business enviornment in the world in Berlin and when it all goes to hell, blame the USA.


































