PostDoc @CarolynBertozzi / PhD @Hecklab / Structural- and Glyco-proteomics, computational modeling / HHMI funded LSRF Fellow / Non-stipendiary EMBO Fellow
Joined July 2020
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(1) Happy to share our latest work: We developed an approach to systematically investigate how glycosylation controls protein function across the proteome—and what goes wrong when it is disrupted.
biorxiv.org/content/10.64898…
Johannes Florian Hevler retweeted
Congratulations to Institute Scholar Laura Dassama for receiving the Protein Society Young Investigator Award in honor of her interdisciplinary work to combat multi-drug resistant bacterial infections: brnw.ch/21x27hG
ALT Congratulations to our Institute Scholar Laura Dassama for receiving the 2026 Protein Science Young Investigator Award in recognition of her work characterizing lipid-binding proteins in bacteria for mitigating multidrug resistance
(8) Bottom line: Understanding glycosylation's functional impact requires more than cataloging which glycans are attached. We hope this resource helps the community dissect glycan-protein relationships at scale!
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(9) Deep gratitude to everyone who made this possible —my postdoc mentor Carolyn Bertozzi, brilliant friends & collaborators @miratsojitra ,@TomislavCaval , @andrenmateus , and my (former) mentors Albert Heck and @savitski_lab!
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Johannes Florian Hevler retweeted
The ChimeraX 1.10 release candidate and daily builds can predict small complexes of proteins, nucleic acids and small molecules using Boltz on your Mac, Windows or Linux computer. rbvi.ucsf.edu/chimerax/data/…
Johannes Florian Hevler retweeted
GoGoGoGoGoGoGoMartini3 now finally published! nature.com/articles/s41467-0…
Johannes Florian Hevler retweeted
Want to know how the ligands interact with proteins beyond model human cell lines? Interested in membrane targets? Check out our High-Throughput PELSA method which allows you do all these cool screenings for dozens of ligands within 2 hours! biorxiv.org/content/10.1101/…
Johannes Florian Hevler retweeted
Check out our recent publication @molcellprot on the hyper-permeability of the synovial compartment for plasma proteins in #rheumatoidarthritis patients! Using a three-level analysis we compared the plasma proteome and the (auto)antibody repertoires between plasma and SF of RA.
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Johannes Florian Hevler retweeted
We sequenced the anti-RSV-F antibody 131-2a by mass spec, then mapped its epitope by cryoEM. It's widely used to study the antigenic landscape of F, but its seq wasn't known. Check it out in our new preprint and find it on Addgene
biorxiv.org/content/10.1101/…
addgene.org/Joost_Snijder/
Johannes Florian Hevler retweeted
Kicking off 2025 with a campaign to get 3D-SNFG implemented in ChimeraX by the kind folk @UCSFChimeraX
Who’s with me?! #glycotime
academic.oup.com/glycob/arti…
Johannes Florian Hevler retweeted
Excited to receive a poster prize at #SSP2024! Big thanks to @SSP2024 for organizing a great conference.
Congratulations to the six #SSP2024 poster award winners on your top-notch pioneering work! And thank you to @naturemethods and @JProteomeRes for supporting these awards and these promising scientists!
Johannes Florian Hevler retweeted
Even more reasons to avoid @BioRender
This is great! @NIAIDNews have launched a collection of public domain illustrations (currently 550 individual icons) bioart.niaid.nih.gov/
Johannes Florian Hevler retweeted
The Liquid Lectin Array (LiLA) paper is out in @CellChemBiol. Congratulations to @Guilher63551077 for this amazing publication and it was my privilege to play a [small] part in this project. #Siglec #Glycotime #Phage #Glycans
cell.com/cell-chemical-biolo…
