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Jack Markham

@JackMarkhamPhD

Medicinal & Computational Chemistry PhD Student with a focus on Cannabinoids 👨‍🔬🧪🧬🖥️

 Eora, Australia
Joined November 2020
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Photo by Jack Markham (@JackMarkhamPhD)Photo by Jack Markham (@JackMarkhamPhD)Photo by Jack Markham (@JackMarkhamPhD)Photo by Jack Markham (@JackMarkhamPhD)Photo by Jack Markham (@JackMarkhamPhD)Photo by Jack Markham (@JackMarkhamPhD)Photo by Jack Markham (@JackMarkhamPhD)Photo by Jack Markham (@JackMarkhamPhD)
It's all things adamantane in our (@Lambert_Usyd) latest synthetic cannabinoid work, out now in @ACSChemNeurosci! We synthesised and evaluated a library of adamantane-derived SCRAs, including fluorinated and deuterated analogues 🧪 🧵 pubs.acs.org/doi/10.1021/acs…
Structure–Activity Relationships, Deuteration, and Fluorination of Synthetic Cannabinoid Receptor...

Structure–Activity Relationships, Deuteration, and Fluorination of Synthetic Cannabinoid Receptor...

Abstract. Synthetic cannabinoid receptor agonists (SCRAs) are a growing class of new psychoactive substances (NPS) commonly derived from an N-alkylated ind

pubs.acs.org
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More SCRA work from @Lambert_Usyd out now in @rsc_medchem! We looked at a series of proteinogenic amino acid-derived SCRAs related to MPP-5F-PICA, MMB-5F-PICA, and MDMB-5F-PICA, investigating the role of chirality in CB1 and CB2 receptor activation. pubs.rsc.org/en/content/arti…
Synthesis and functional evaluation of proteinogenic amino acid-derived synthetic cannabinoid...

Synthesis and functional evaluation of proteinogenic amino acid-derived synthetic cannabinoid...

Synthetic cannabinoid receptor agonists (SCRAs) comprise the second largest class of new psychoactive substances (NPS), and typically α-amino acid moieties

pubs.rsc.org
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Latest work from @Lambert_Usyd is online in @ACSChemNeurosci! In another great collaboration with @christophestove et al., we looked at the recently detected synthetic cannabinoid ADB-HEXINACA and related analogues as emerging NPS🧪🔍 pubs.acs.org/doi/10.1021/acs…
Synthesis and Functional Evaluation of Synthetic Cannabinoid Receptor Agonists Related to ADB-HEX...

Synthesis and Functional Evaluation of Synthetic Cannabinoid Receptor Agonists Related to ADB-HEX...

Abstract. ADB-HEXINACA has been recently reported as a synthetic cannabinoid receptor agonist (SCRA), one of the largest classes of new psychoactive substa

pubs.acs.org
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“You’ve got a bizarre situation in which you can grow opium poppies behind a farm fence, but if you grow cannabis you need [secure] facilities and dogs,” 🗨️ @iainsmcgregor Read @JordsBaker's @smh feature on #medicalcannabis ft. the Lambert Initiative👐 smh.com.au/national/buying-l…
Buying legal marijuana is as easy as picking up the phone. Here’s how I did it

Buying legal marijuana is as easy as picking up the phone. Here’s how I did it

Top-quality legal cannabis can be in your letterbox within days. And prescriptions have soared by almost 4000 per cent.

smh.com.au
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Our latest paper from @Lambert_Usyd on 4-fluoro and 4-cyanobutyl substituted synthetic cannabinoids is online today! tl;dr: most compounds assayed were moderate to high potency and efficacy CB1 agonists, and should be monitored as emerging NPS 🧪🔍 frontiersin.org/articles/10.…
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📚🤓 First Journal Club for 2022 @ LI, it's been a long time coming but now we can finally argue in person! Ft. Maia yelling at @EA_Cairns, @MA_BEDOYAPEREZ, @TheCannabisGuyy, Ayshe, @JackMarkhamPhD, @eric_sparkes, Tom, Sam and @DuckyMcCartney 🥳
Image from Lambert Initiative (@Lambert_Usyd)
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#icrs2021 day 2. Late breaking research submission - Multiple overnight virtual conference attendance significantly increases snacking amongst academics. We’re (@Lambert_Usyd) on Twitter again, for all your questions 👩‍🔬🧑‍🔬👨‍🔬
Image from Elizabeth Cairns (@EA_Cairns)
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