Medical Oncologist and translational researcher interested in genomic diagnostics, liquid biopsy, and investigational therapeutics.
Seattle, WA
Joined September 2019
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Joe Hiatt retweeted
Excited to share our latest in @CCR_AACR, collab w @sriv4000 and led by @JoeHiattMDPHD on LSD1 inhibition augmenting immune responses in SCLC. The project was supported by the @theNCI Lung SPORE and has led to a new clinical trial @fredhutch
aacrjournals.org/clincancerr… 1/X
Joe Hiatt retweeted
So today I called for Progression Free Survival (PFS) to be renamed as Progression Free Duration (PFD) because “improved PFS” incorrectly sends out a signal to patients that survival is prolonged— when in reality it may or may not be prolonged & can even be worse. @TheLancetOncol
Joe Hiatt retweeted
Simply points for #IMW2019 attendees to keep in mind.
- Ph II studies are a hypothesis — not proof
- “Activity” is not = clinical benefit.
- Clinical benefit = improved OS or validated PRO; plus safety
- PFS, MRD-, CR = Surrogate end points @TheLancet
thelancet.com/journals/lance…
Joe Hiatt retweeted
Survival with TKI's 2-fold worse in patients who have the highest out of pocket cost! Seen in patients with Medicare! Congratulations on great study Dr. Goulart, @ScottDRamsey @junger47 #ASCOQLTY19
