Senior bioinformatic scientist at St. Jude Children's Research Hospital
Memphis
Joined January 2011
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Kyle S Smith retweeted
The Northcott lab conducted an extensive re-analysis of a single-cell transcriptional atlas of human cerebellar development originally published in 2022. During this process, we identified significant concerns related to data integrity and interpretation,
Kyle S Smith retweeted
Where does medulloblastoma come from? St. Jude scientists have helped figure it out. bit.ly/3xIYo4i
@drpaulnorthcott @nature #childhoodcancer #braintumor #CCAM #CancerResearch
Kyle S Smith retweeted
St. Jude scientists have discovered the developmental origins for Group 3 and Group 4 medulloblastoma which may help improve research models and potential therapeutics. bit.ly/3S2eT3J @nature @drpaulnorthcott #childhoodcancer #CCAM
Kyle S Smith retweeted
1/5 Our new paper resolving the developmental origins of Group-3 Medulloblastoma is out @Nature
Previously the cellular origins of Group3-MB were unknown despite multiple cross-species efforts comparing MB tumors to mouse cerebellar single-cell atlases.
nature.com/articles/s41586-0…
Kyle S Smith retweeted
UPDATE: the suspect is still at large. If you do not have to be out, stay indoors until this is resolved.
Kyle S Smith retweeted
As we bid a final goodbye today we ll fondly remember Prof. Zoltan Patay for his immeasurable contributions to #pedineurorad
@drmankad
@StJudeResearch @The_ASPNR @ESNRad @zguroztekin @drpaulnorthcott @TYPoussaintMD @draash @hakimaalhashimi @LorenzoPinelli @nihaal08 @MirskyDavid
Kyle S Smith retweeted
Excited to share our latest pre-print building a single-nucleus atlas of pediatric rhabdomyosarcoma. We report heterogeneity within 18 patient tumors, and 18 xenografts from those same patient tissues, and show treatment selects for mesoderm-like cells #sarcoma @StJudeResearch
