President @LifespanRI, Inventor @DisneyStreaming. Leading advocate for life extension, blockchain, and DeSci. @LifeNoggin,@Vita_DAO,@Gitcoin. Modern Gilgamesh.

New York
Joined April 2009
Do people want longer lifespans, or just healthspan? Should longevity advocates avoid “life extension,” or lean into it? I just published a preprint exploring this, drawing on mythology & modern data, & what it means for advancing longevity research. zenodo.org/records/19656500
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Today is International Longevity Day. At Lifespan Research Institute, we’re working toward a future where growing older doesn’t have to mean an ever-increasing burden of disease. That future won’t come from a single discovery. It takes an ecosystem. At LRI, we work across that ecosystem to drive the field forward on multiple fronts: 📰 Educating through thousands of articles and resources 📈 Catalyzing millions in longevity biotech investment 🔬 Translating research toward the clinic 🤝 Building tools, advocacy & collaborations With your support, we can do even more, from expanding our Rejuvenation Roadmap and advancing therapies targeting mitochondrial dysfunction and senescent cells, to developing digital biomarkers that can help us better measure human aging and building the connections that turn promising science into real-world impact. At a time when the future is so often defined by what may go wrong, we believe it’s worth investing in what can go right. If you believe a healthier future is worth building, stand with LRI this International Longevity Day. 💙 Support our work: lifespan.io/support We welcome one-time and recurring donations, gifts of stock, cryptocurrency, and through donor-advised funds. For larger gifts or matching support, please contact [email protected] #InternationalLongevityDay #LongevityResearch #HealthyLongevity
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I'm so happy to see this amazing film concept get the attention it deserves, from @xprize and others. It's been many years since Tim first discussed it with me and the team at @LifespanRI, and the timing of such a project moving forward now could not be more important.
In this latest Lifespan Interview, filmmaker Tim Maupin shares recent updates on the development of "The Last Generation to Die", a near-future film about what happens when the first true rejuvenation technologies arrive, including its recent selection as a top-65 contender in the Future Vision @xprize Tim's history working with the team at @LifespanRI, and the creation of @JellyfishDAO. 👉 Read more: lifespan.io/the-last-generat…
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keithcomito.eth retweeted
In our August 2026 Rejuvenation Roundup: new research on senescent cells, brain aging, metabolic health, thymus regeneration and exercise, plus interviews on precision health and tracking health rather than just disease. We also highlight a new AI “virtual cell” model and an LRI white paper making the economic case for democratizing rejuvenation technologies. 👉 Read more: lifespan.io/rejuvenation-rou…
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The PLG Intelligence Dashboard enters closed alpha on Tuesday. During this phase, all PLG donors will be given full access to the Intelligence Dashboard and all of its powerful data research tools. If you donated to the campaign, check your inbox on Tuesday for login details! 1/2
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keithcomito.eth retweeted
THE LAST GENERATION TO DIE is in the Top 50 of the Future Vision XPRIZE. 2,500 films entered. Fifty remain. Written & directed by Tim Maupin Watch it on the official showcase page: fvxp.moonshots.com/creator/t… #FutureVisionXPRIZE @XPRIZE @Google @PeterDiamandis
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keithcomito.eth retweeted
In this new whitepaper, we explore why democratizing access to rejuvenation therapies is an economic imperative, showing how extending healthy lifespans can reduce healthcare costs, strengthen productivity, and create broad societal and economic benefits. 👉 Read more: ow.ly/XUPf50ZwQQy
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keithcomito.eth retweeted
In this latest Lifespan Interview, Gabriel Cian discusses how the Longevity 2060 ecosystem has evolved since last year’s Forum, and how he thinks about investment, scientific credibility, health optimization, policy, and the future of longevity in Europe. 👉 Read more: ow.ly/XSCE50Zn1up
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keithcomito.eth retweeted
In our June 2026 Rejuvenation Roundup, we highlight the latest efforts to address aging, through various approaches such as delving deeply into RNA and protein interactions. 👉 Read more: lifespan.io/rejuvenation-rou…
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keithcomito.eth retweeted
NeuroAge Therapeutics has announced Younger 2027, a six-month biological aging contest in which competitors are measured on a clinical-grade aging panel and retested six months later. 👉 Read the press release: lifespan.io/neuroage-therape…
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I’m looking forward to speaking at the 2026 Medical Innovation Olympics on Oct 16, bringing together healthcare innovators, scientists, entrepreneurs, investors, and industry leaders. Registration is open now: medicalinnovationolympics.co… and you can use code LIFESPANIO for 40% off.
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keithcomito.eth retweeted
In our May 2026 Rejuvenation Roundup, we highlight advances in cellular reprogramming, AI-driven drug discovery, immunotherapy, therapies for cardiovascular disease and Alzheimer’s, and insights into the longevity research landscape. 👉 Read more: lifespan.io/rejuvenation-rou…
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keithcomito.eth retweeted
Will you be in NYC during @Techweek_? Don't miss the @LongevityGL AI x Longevity Summit on June 4-5, bringing together researchers, founders, investors, and more. Agenda and registration: ow.ly/eBQT50Z5JIw
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keithcomito.eth retweeted
In this latest Lifespan Interview, Matthew O'Connor discusses @Cyclarity Therapeutics 's recent successful phase 1 trial demonstrating removal of oxidized cholesterol (7KC) in humans. 👉 Read more: lifespan.io/matthew-oconnor-…
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keithcomito.eth retweeted
The April Rejuvenation Roundup is live! From sedentary zoo penguins aging faster to NAD+ combinations restoring function in mice and new warnings on senolytics. Learn about progress alongside meaningful risks. lifespan.io/rejuvenation-rou…
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keithcomito.eth retweeted
Replying to @LifespanRI
@LifespanRI CEO and president @KeithComito takes the stage at RejuveAI x Infinita City Longevity Biomarkers Conference, live in Roatan, HN @infinitacity @ProsperaGlobal
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keithcomito.eth retweeted
What were the highs and lows of 2025 in geroscience? What should we expect in 2026? We asked five prominent geroscientists: @prof_horvath, @geochurch, @AndreaBMaier, @mkaeberlein, and Oliver Medvedik. lifespan.io/news/geroscience… By: @ArkadyMazin
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Question: Q: "Where can I find a rejuvenation roadmap with some of the most promising rejuvenation therapies and technologies in development A: Right here, courtesy @KeithComito and his @LifespanRI team: 🧪 🔗lifespan.io/road-maps/the-re… * Special thanks to @KarlPfleger at AgingBiotech.info, "whose therapy database helped to inform this roadmap."
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As the year comes to a close, we’re building momentum for what’s next. LRI advances the science that targets aging, & the systems that turn breakthroughs into real-world impact. Join us for another year of driving longer, healthier lives for all! lifespan.io/end-of-year-2025…
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Great work by @JellyfishDAO. Now more than ever it is important to paint what positive visions of the future can look like, and its gratifying to see the old “Interviews from the Future” ideas Tim brainstormed with us @LifespanRI back in 2021 now coming to life.
What if our descendants look back at our acceptance of aging the way we look back at medieval medicine? We interviewed them. Dystopian futures are easy to imagine. Optimistic futures take vision and courage to build. VOICES FROM 2099:
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