James Kirby retweeted
Burkholderia cepacia causes disease in 🫁 of people with cystic fibrosis, an environment totally unlike standard susceptibility testing conditions. Today at #ASMicrobe Anusha Shukla presented her work on Bcc in artificial sputum medium 🧫🥼🧪 TBKLab.org
James Kirby retweeted
Did you know that avibactam has intrinsic antibacterial activity, mediated by inhibition of penicillin-binding protein 2? Here’s the amazing Dr. Michelle Naegeli @drshigelly presenting a poster from our lab today at #ASMicrobe
James Kirby retweeted
Yanqin Huang of @KirbyLabMicrobe presenting on the all-oral triple combination of omadacycline + azithromycin + clofazimine for M. abscessus #ASMicrobe
James Kirby retweeted
Congratulations to Dr. Jeannie Lee (@XistHarvard), recipient of IRSF's Innovation Award Grant. This project focuses on restoring MECP2 in patients to potentially treat and cure #Rettsyndrome. More on research: buff.ly/3Ye0Qed #GeneTherapy
James Kirby retweeted
Plasmid of the Day
pMOD3-mWasabi-nat
Depositor: @KirbyLabMicrobe
Purpose: Bacterial mWasabi promoter trap
hubs.la/Q01gmyrY0
James Kirby retweeted
Congratulations to the awardees of our research funding opportunity @BIDMChealth and IDX20! We look forward to following your progress on #COVID19 research. reaganudall.org/news-and-eve…
James Kirby retweeted
Happy medical laboratory professionals week! We could not do our jobs without you! We see you and value you. ❤ @Thea_BK @KirbyLabMicrobe Twitterless Robert @romneyinla @RodneyRohde @BurnhamBugDoc and many many others!
It’s Medical Laboratory Professionals Week! Celebrate and thank laboratory professionals for their hard work, dedication, and service.
Know an awesome laboratory professional? Tag them below and visit bit.ly/labweek21.
James Kirby retweeted
"Junk DNA" B2 and ALU make self-cleaving ribozymes!
An honor that our paper was given the Cozzarelli Prize. Congrats to coauthors A Hernandez, @ZovoilisLab, C Cifuentes-Rojas, Lu Han, @Bojan53387482!! @MGHMolBio @MGH_RI
pnas.org/content/117/1/415
The Editorial Board of PNAS has selected six papers published in 2020 to receive the Cozzarelli Prize, an award that recognizes outstanding contributions to the scientific discipline represented by the NAS. See the list of recipients here: ow.ly/8qj750DZaZC
James Kirby retweeted
A Unified View: Motif-driven interactions between RNA and PRC2 are rheostats that regulate transcription elongation !
- resolving the mystery of why RNA-PRC2 complexes occur within active genes, and how specificity is achieved
Free read: rdcu.be/cc2Ee
ALT https://www.nature.com/articles/s41594-020-00535-9
James Kirby retweeted
Just accepted!
"Children with asymptomatic SARS-CoV-2 infection had lower levels of virus... than symptomatic children, but timing of infection relative to diagnosis likely impacted levels in asymptomatic children."
bit.ly/3kmAX89 @ASMicrobiology
James Kirby retweeted
1 h malaria detection that meets WHO recommended standards using SHERLOCK system: pnas.org/content/early/2020/…
James Kirby retweeted
X chromosomes play TAG --> YOU'RE IT !! See how sex chromosomes decide who will stay 'ON' through PAIRING, an RNA decapping enzyme, and CTCF:
nature.com/articles/s41556-0…
James Kirby retweeted
Are you confused about the relationship between Xist RNA, Polycomb recruitment (PRC2, PRC1), and gene silencing? Please read our new study for an integrated view: "Xist Repeats A and B Account for Two Distinct Phases of X Inactivation Establishment"
disq.us/t/3ph2pac
James Kirby retweeted
Is Xi-reactivation safe in vivo? For answers, please read: "Widespread organ tolerance to Xist loss and X reactivation ..."
pnas.org/content/early/2020/… @RSRT @Rettsyndrome @CDKL5USA @MGHMolBio @MGH_RI @NIMHgov
James Kirby retweeted
Burkholderia cenocepacia producing a very nice pigment (and a nice freshly-dug potato smell to go with it)
James Kirby retweeted
I’ve often wondered why body lice spread disease but head lice don’t, although they belong to the same species - turns out it may have to do with a more robust immune response to bacterial infection by head lice: entomologytoday.org/2014/01/… via @EntsocAmerica
James Kirby retweeted
MacConkey agar is one of the most recognizable media in the microbiology laboratory. In a new Bugs & Drugs article, we discuss the history of this ubiquitous medium and how the formulation changed over its 120 year history. skyw.io/lnr1mt #ASMClinMicro
James Kirby retweeted
New #AACJournal minireview: new treatment options against carbapenem-resistant A. baumanii (CRAB) infections #ASMClinMicro aac.asm.org/cgi/reprint/63/1…
James Kirby retweeted
The 2 faces of Xist RNA: (1) Attractant for silencers, and (2) Repellant for activators. Our new paper shows how it repels SWI/SNF-BRG1 from the inactive X. Read about it here - for free!
rdcu.be/bhPaK
or
nature.com/articles/s41594-0…
James Kirby retweeted
The inoculum effect is sufficiently pronounced for meropenem and cefepime in MDR Gram-negative pathogens to affect categorical interpretations during standard lab testing #AACJournal ow.ly/5Pvp30lcZOc #ASMClinMicro
