Lucas Zeiger (@LBZeiger) header
Lucas Zeiger (@LBZeiger) profile picture

Lucas Zeiger

@LBZeiger

Cancer Reasearch @CRUK_BI in Glasgow. Molecular Medicine at Medical Uni Innsbruck @imed_tweets before.

 Glasgow; Innsbruck
Joined February 2016
  • Tweets52
  • Following451
  • Followers251
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Photo by Lucas Zeiger (@LBZeiger)
RESEARCH | Vande Voorde et al. (@CRUK_BI): Authors investigate the potential of untargeted #metabolomics as a stratification tool for colorectal cancer & present a pipeline to uncover metabolic vulnerabilities based on its genetic origin #cancerresearch nature.com/articles/s42255-0…

Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeu...

Nature Metabolism - In this study, Vande Voorde et al. investigate the potential of untargeted metabolomics as a stratification tool for colorectal cancer (CRC). They present a comprehensive...

nature.com
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Lucas Zeiger retweeted
Johan VV (@Joharrr) profile picture
Johan VV@Joharrr16 Aug 2023
Thanks for covering our story! And to our lovely collaborators: @NPL @CRUK_BI @imperialcollege @UofGCancerSci @LabEdwards @AstraZeneca F.Crick Institute @KU_Leuven @Rafabolism @LBZeiger @KafPennel @krikirschner @bernthie @VivianLiLab @DSumpton @bowelsurgeon @owen_sansom & more!
Cancer Grand Challenges (@CancerGrand) profile pictureCancer Grand Challenges
@CancerGrand16 Aug 2023
📢 New blog post Hear from @Joharrr of team Rosetta @CRUK_BI about the team’s new @NatMetabolism study, where they utilised a variety of mass spectrometry techniques to investigate the metabolic consequences of common oncogenic events in #ColorectalCancer bit.ly/3OzzHix
The power of combining mass spectrometry techniques to interrogate the cancer metabolome.

ALT The power of combining mass spectrometry techniques to interrogate the cancer metabolome.

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Johan VV (@Joharrr) profile picture
Johan VV@Joharrr14 Aug 2023
We’re very excited to share the latest findings of @cancergrand Team Rosetta, out in @NatMetabolism now!!! nature.com/articles/s42255-0…
Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeu...

Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeu...

Nature Metabolism - In this study, Vande Voorde et al. investigate the potential of untargeted metabolomics as a stratification tool for colorectal cancer (CRC). They present a comprehensive...

nature.com
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🆕 Paper from @Joharrr @owen_sansom & colleagues where they use mass-spectrometry based metabolomics to investigate the metabolic impact of colorectal cancer driver mutations. biorxiv.org/content/10.1101/…
Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeu...

Metabolic profiling stratifies colorectal cancer and reveals adenosylhomocysteinase as a therapeu...

With colorectal cancer (CRC) being the second most common cause of cancer-related deaths worldwide[1][1], there is an urgent need for better diagnostic tools and new, more targeted therapies. Here we...

biorxiv.org
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Dominika (@domi_89) profile picture
Dominika@domi_8910 Aug 2022
Proud to share my PhD research from @CRUK_BI, supervised by Danny T Huang. With @Mark_A_Nakasone and @BrianOSmith1967, we studied the elusive interaction between #MDM2 #E3 ligase and p14ARF tumor suppressor. Published by @LSAjournal life-science-alliance.org/co…
Bivalent binding of p14ARF to MDM2 RING and acidic domains inhibits E3 ligase function

Bivalent binding of p14ARF to MDM2 RING and acidic domains inhibits E3 ligase function

ARF tumor suppressor protein is a key regulator of the MDM2-p53 signaling axis. ARF interferes with MDM2-mediated ubiquitination and degradation of p53 by sequestering MDM2 in the nucleolus and...

life-science-alliance.org
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Thank you all for attending! The organisers: @ILikeHelicases @IPuoti @SYouhani @vBarthet @dedonatis_m @Martha_Z @knikol7 @mfrancescallega @LBZeiger Martina Chris Michalis
Image from IPSCC Conference (@ipscconf)
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We are back! Come and join us for a virtual edition of IPSCC. We have a great line up of keynote speakers @LMachesky @FrezzaLab @RossCagan as well as student talks,poster sessions,career workshops and virtual social events! The registration is open now! @CR_UK @CRUK_BI @UofGMVLS
Image from IPSCC Conference (@ipscconf)
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Replying to @UofGMVLS @CancerWithStyle @UofGlasgow @UofGCancerSci @HelgasonLab @VignirHelgason @POG_LRC
💙In her memory, this fundraiser is planned by colleagues @HelgasonLab bit.ly/3d707XI

Walk All Over Cancer In Memory of Zuzanka

In memory of my friend, high-school and uni classmate and fellow Czech living in Scotland. As the sad news of past days slowly emerge I am walking 10,000 steps a day throughout March to help beat...

fundraise.cancerresearchuk.org
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It's International Day of Women and Girls in Science! Here, our Research Manager @Anna_Lakey19 talks to Sigrid Fey, @PancreaticCanUK Future Leader @CRUK_BI about her work in #PancreaticCancer research and experience as a woman in science: pancreaticcancer.org.uk/news… #WomeninScience
Image from Pancreatic Cancer UK (@PancreaticCanUK)
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1/13 COVID-19 had a significant impact on our research activity but our researchers adapted brilliantly and work @CRUK_BI continued to thrive. This #WorldCancerDay #WCD2021 , we're highlighting just some of the successes from the past year:
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Lab Xmas Party- great evening! @owen_sansom @RafaPhD @adcampbell01
Image from Rachel Ridgway (@rachel_ridgway)
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Just published #OnlineFirst: MNK inhibition sensitizes #KRAS-mutant colorectal cancer to mTORC1 inhibition by reducing eIF4E phosphorylation and c-#MYC expression. @owen_sansom @CRUK_BI @UofGCancerSci bit.ly/3nsr76j
Image from Cancer Discovery (@CD_AACR)
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