Is Latest Medical Research Agree to four Temperaments of the Body No. Modern medical research does not confirm the traditional four temperaments as a scientifically proven system for classifying the human body. However, science does recognize that people differ in personality, emotional reactions, energy levels, and behavior. The traditional theory comes from ancient Greek medicine and describes four temperaments: sanguine, choleric, melancholic, and phlegmatic. It proposed that these types were determined by the balance of four bodily fluids: blood, yellow bile, black bile, and phlegm. Modern medicine does not accept this explanation because there is no reliable scientific evidence that these fluids determine a person's temperament or health. ScienceDirect Topics +1 What does the latest research say? A 2026 literature review examined research on the traditional four temperaments and found that the available studies had important methodological weaknesses. The authors concluded that more rigorous research is needed to establish whether this classification is scientifically valid. rbp.celg.org.br Modern research does support the idea that temperament has biological aspects. For example, a 2025 study published in Molecular Psychiatry investigated links between temperament, brain activity, and neurotransmitters. However, this does not prove the traditional four-temperament theory. Molecular Psychiatry Conclusion: The four temperaments may be useful as a traditional way to describe personality, but they are not an established medical method for diagnosing illness or deciding which foods and treatments a person needs. One important question: Are you asking about the four temperaments (sanguine, choleric, melancholic, phlegmatic) or the traditional Eastern medical concepts of hot, cold, dry, and moist body constitutions? They are related historically but are not exactly the same system.