B cells | Macrophages | Osteomorphs | #PrecisionImmunology | Cancer cell dormancy

Sydney, Australia
Joined September 2019
My top 10 #ASH24 abstracts for plasma cell disorders/multiple myeloma #mmsm @ASH_hematology #mmsm 🧵
3
40
3
115
27,151
An incredible #plasmacell undergoing #apoptosis seen at high resolution!🤩 #microscopymonday #EMmonday
10
65
4
475
25,617
Only TWO DAYS LEFT to apply for this year's #ACDS Prize for Outstanding ECRs! 🏆 Awardees will receive a medal, $500 cash prize, and are invited to present an ACDS Seminar in 2025 🤩 Learn more and apply now at australasiancelldeathsociety…
📢 ICYMI: Applications for our 2024 ACDS Prize for Outstanding ECRs are NOW OPEN! 🏆 Awarded annually, this Prize recognises the stellar contributions of our ECRs to cell death research both locally & internationally 🤩 Must close 5pm AEST Friday 18 October - Apply now! ⏳
6
6
1,082
Popper used to begin his lecture course on the philosophy of science by asking the students simply to ‘observe’. Then he would wait in silence for one of them to ask what they were supposed to observe. This was his way of demonstrating one of many flaws in the empiricism that is still part of common sense today. So he would explain to them that scientific observation is impossible without pre-existing knowledge about what to look at, what to look for, how to look, and how to interpret what one sees. And he would explain that, therefore, theory has to come first. It has to be conjectured, not derived. @DavidDeutschOxf
60
482
68
2,926
444,210
I am happy to share a large part of my postdoctoral work published in @SciImmunology! Using LIPSTIC, we identify and characterize antigen-presenting dendritic cells (DCs) in the tumor-draining lymph node and tumor microenvironment science.org/doi/10.1126/scii…
14
26
1
200
20,855
Multiple Sclerosis is entering its 2024 ERA – that means new treatments on the horizon and a new changes to the McDonald DIAGNOSTIC CRITERIA! Some of these changes are quite significant – to get everyone up to speed I made this thread!
10
169
8
1,092
186,667
An amazing few days talking immunology and clinical translation. Thanks to everyone who was involved! Watch this space in the years ahead for the clinical impacts from the passionate student and ECR researchers who were there.
This Post is from an account that no longer exists. Learn more
1
9
866
Protein isoform-centric therapeutics: expanding targets and increasing specificity tinyurl.com/2v5c3us8 Many genes encode multiple protein isoforms. This new review discusses targeting isoforms as a route to drugs with greater specificity and fewer adverse effects
1
38
1
176
20,321
Phan Lab retweeted
Using concepts from multi-modal #Omics data integration, Extensible Immunofluorescence (ExIF; shorturl.at/d3N75) allows highly multiplexed single cell analyses of complex biology (here of #EMT) by integrating standard 4-plex #fluorescenceimaging data via virtual labelling.
1
4
11
1,286
Phan Lab retweeted
Scott Mueller@SMuellerLab17 Aug 2024
Cecelia: Quantitative multi-dimensional image analysis made easier! No jumping between several software packages. github.com/schienstockd/cece… doi.org/10.1101/2024.08.13.6…
1
9
23
3,772
Abundance and subtype heterogeneity of tumor-associated B cells at the pan-cancer level reveals atypical B cells that can communicate with CD4 T cells and have prognostic potential @CellCellPress cell.com/cell/fulltext/S0092…
21
1
87
11,225
Most T cells recirculate and visit many lymphoid organs, but different lymph nodes each retain unique TCR repertoires @ScienceAdvances science.org/doi/10.1126/scia…
36
1
180
19,344
The most important geospatial concept? Spatial Autocorrelation. It can make the difference between spurious and accurate results. Here’s what you need to know about it:
14
318
14
1,952
331,663
Super excited to share that ENGRAM is out today! ENGRAM cells are programmed to write their histories into the genome, recording the intensity, duration, and order of biological events simultaneously. nature.com/articles/s41586-0…
13
126
16
473
83,023
Check out our latest #publication @ScienceAdvances demonstrating NID2 targeting in #pancreatic cancer @GarvanInstitute @INCITeCentre @thomasrcox @PanKind_APCF see link science.org/doi/epdf/10.1126…
10
34
2,008
Can single-cell omics enhance clinical studies? Find out @CellCellPress 👀cell.com/cell/fulltext/S0092… about the potential of single-cell omics for monitoring in vivo target engagement of immunomodulatory drugs and for patient stratification for precision medicine approaches. [1/8]
4
32
2
104
16,928