Neurobiologist & Neurologist. My lab focuses on the biology of astrocytes/neurons & develops organoid disease models to study their role in neurodegeneration.
University of Cambridge
Joined September 2017
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Stem Cell Models of Neurodegeneration International Symposium - scmnd.com/Speakers.html - a meeting to join!
Andras Lakatos retweeted
Interested in mechanobiology, transcription factors and stem cell differentiation? Please check out this postdoc opportunity between my lab @ImperialLifeSci and the lab of Maxim Molodtsov @molodtsovlab (Deadline: 6 January 2027):
crick.ac.uk/careers-study/va…
With Srinjan Basu, led by Alex Kingston, our new collaborative study has been exploring the effect of mechanical forces on stem cell fate using cortical organoids - now covered in preLights!
Mechanical forces don’t just shape the cortex, they instruct it 🧠
Kingston et al. @LakatosLab, @srinjan_basu show LINC-mediated nuclear mechanosensing governs progenitor fate, neuronal identity & human cortical patterning.
#preLight by @kparashar1998⬇️
prelights.biologists.com/hig…
5 year old brain organoids!
newscientist.com/article/258…
Cambridge is to lead a £20m @The_MRC Hub to transform the development of new medicines using stem cells and AI.
Led by the Cambridge Stem Cell Institute, it will develop alternatives to the use of animals in research 👉 cam.ac.uk/research/news/camb…
Andras Lakatos retweeted
Proud to share our latest bioRxiv with Lakatos lab @LakatosLab showing how niche-specific mechanotransduction guides human cortical patterning and cell fate acquisition. How does a tissue's mechanical environment shape which cells it makes, and when? 1/n
biorxiv.org/content/10.64898…
Connectoids: Our latest Human Brain-Spinal Cord-Muscle Organoid-Slice Connectoid model: cell.com/cell-reports/fullte…
@Cambridge_Uni
@The_MRC
@SCICambridge
@BrainRepair_VGB
@SpinalResearch
@organoidscience
@OrganoidSphero1
@OrganoidAtlas
Our latest Human Brain-Spinal Cord-Muscle Organoid-Slice Connectoid model:
cam.ac.uk/research/news/lab-…
@Cambridge_Uni @The_MRC @SCICambridge @BrainRepair_VGB @SpinalResearch @organoidscience @OrganoidSphero1 @OrganoidAtlas
Thanks Vanja!
Beautiful work by @LakatosLab !!
A human corticospinal organoid-slice connectoid model informs enhancer strategies for post-injury axon regrowth: Cell Reports cell.com/cell-reports/fullte…
Andras Lakatos retweeted
New pre-print from our lab here:
biorxiv.org/content/10.1101/…
Andras Lakatos retweeted
The first @EMBO #Astrocyte #Meeting was a success. Thanks to our engaging lineup of excellent speakers, brilliant trainees & essential @DiBio_UniPD volunteers. Looking forward to the next iteration! @LauCiviero @theOlgaSin @wonsukchung Matthew.Holt
Origin and cell type specificity of mitochondrial DNA mutations in C9ORF72 ALS-FTLD human brain organoids | Science Advances science.org/doi/abs/10.1126/…
Andras Lakatos retweeted
This is important: without urgent action clinical academia in the UK is at serious risk of dying out.
ukri.org/news/report-calls-f…
Andras Lakatos retweeted
ANOTHER exceptional 3D organoid models session at #SCMND2025? What a treat!
Come join us in Edinburgh this March for some incredible science! Submit your abstract and register here 👉👉scmnd.com/
@UKDRI @bhuvaneish @LakatosLab @NeuralStemCells
#iPSC #organoids
Andras Lakatos retweeted
Interested in #oligodendrocyte metabolism and/or #multiplesclerosis? Our paper is now at Biorxiv! We show that oligos express MCT2, the high affinity monocarboxylate transporter, well known for supplying neurons with astrocyte-derived lactate (astro-neuron lactate shuttle)👇
Monocarboxylate transporter 2 is required for the maintenance of myelin and axonal integrity by oligodendrocytes biorxiv.org/cgi/content/shor… #biorxiv_neursci
A Postdoctoral Research Associate post is available in the lab in Human Organoid Neurobiology and ALS/MND Research - see our job advert in Nature Careers
nature.com/naturecareers/job…
