Internal Medicine Resident @BrighamWomens @harvardmed, genomics @broadinstitute @icahnmountsinai
Boston, MA
Joined June 2020
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🧵 1/ It’s not enough to deploy a model, even one with good discrimination. Why? We risk miscalibration and poorer decision-making for hundreds of thousands of patients.
I’m delighted to share our work published in @npjDigitalMed.
nature.com/articles/s41746-0…
Statins are our first-line tool against ASCVD, but not everyone hits their LDL-C target, and we usually only find out months later, after the follow-up lipid panel.
Can we know in advance? New in @Circ_Gen : a multi-ancestry PRS for statin non-goal response.
PRS-NGR replicates across multiple ancestries - African, European, and Latin American and multiple biobanks @uk_biobank Biobank Japan
Full paper here: ahajournals.org/doi/10.1161/…
Lathan Liou retweeted
#medstudents if you like playing @NYTGames Connections or @openevidence Synapses, try out ✨Clerkship Connections✨! It's a fun little game I built based on the same concept that also helps you study for your next #medschool shelf exam :)
🔗 Try it here! clerkshipconnections.com
Most of what we know in genomics is still built on Eurocentric data. We need genomic insights that reflect global diversity.
@ChristaCaggiano and I reviewed some of the key efforts expanding genomic discovery in underrepresented populations.👇
As part of The Genomics Preprint Club, we review efforts by @SineadCullina Ravi Mandla @Yunfeng_Ruan @YJHuang086
Lathan Liou retweeted
Can med students learn hands-on skills in data science and AI? Yes! We describe 2 national #datathons designed by and for @mdplus__ med students, now out in @JMIR_MedicalEd. With @EmilyLLeventhal, Lawrence Huang, @CLARAmediSUN, Steve Stephen, @LathanLiou #MedEd 📄 (1/n)
The relationship between statistics education and medical trainees is often...rocky. I penned an article exploring ways we can update the way we frame teaching statistics in medicine 🩺 (1/2)
#MedTwitter
journals.sagepub.com/doi/ful…
Fun thinking this through with Dr. Murray Mittleman @HarvardChanSPH
Lathan Liou retweeted
Motivated by the goal of precision medicine, @LathanLiou et. al. demonstrate subtyping of coronary artery disease is achievable using clinical and genomic risk factors. @LathanLiou @Juditperala @GeneticHeartDoc @kovacic_jason @paul_f_oreilly
ahajrnls.org/3ZwA6rA
Lathan Liou retweeted
🧬New editorial w/ @MathewMaurer @LathanLiou: current inadequacies in access to #genetics care in the US hinder ATTRv detection/treatment, disproportionately so in minority communities; solutions proposed! @GeneticCouns @MountSinaiHeart @GeneticsSociety ahajournals.org/doi/10.1161/…
Excited to share our article in @CircAHA where we discuss the importance of increasing #HealthEquity in #Genetics care for cardiac amyloidosis 🧬🫀. Thread below for summarized key points! (1/n)
@GeneticHeartDoc @MathewMaurer
