Laboratory of Stavros Lomvardas, PhD Zuckerman Mind Brain Behavior Institute | Jerome Greene Science Ctr https://xitter.cf/t.co/OPR19GE561

Columbia University, NYC, NY
Joined October 2021
Seminal discovery by @SternbergLab - congrats to the team and many thanks for making beautiful science!
1/5 Telomerase has long been linked to chromosome maintenance in eukaryotes. Now, we show that telomerase-like activity is also present in bacteria, shedding new light on its ancient origins. Excited to share that our work on DRT10 is now out in @Nature! nature.com/articles/s41586-0…
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Officially out in Nature Communications: Structural and functional regulation of GluA2 AMPA receptor by inhibitory auxiliary subunits GSG1L and TARP g5 and by epilepsy-associated disease mutations. @shantigangwar @MariaKarela3 @MKCMU nature.com/articles/s41467-0…
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LomvardasLab retweeted
Congratulations to #HHMIInvestigator Charles Zuker, winner of the 2026 Wolf Prize in Medicine! Zuker's groundbreaking research into taste has helped reveal how the brain transforms signals from the outside world into perceptions, actions, & behaviors: bit.ly/4AIg7Ib.
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Amazing story showing how pairing basic research with medicine results in clinical “miracles”. and so inspiring to know that our own Dr. Lustig from @Columbia had key contributions in this inspiring story
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So nice to see a transformational scientist being honored and recognized at the highest level. Congrats Charles!
ANNOUNCING THE 2026 WOLF PRIZE LAUREATE IN MEDICINE The 2026 Wolf Prize in Medicine is awarded to Charles S. Zuker of Columbia University and the Howard Hughes Medical Institute, “for revolutionizing our understanding of taste, the last of our senses to be elucidated.” Sweet. Sour. Bitter. Salty. Umami: Zuker’s research revealed the cells and receptors responsible for each of the five basic tastes - and showed how those signals are encoded and represented in the brain. His experiments went even further: by rewiring taste receptors in mice, his team demonstrated that what makes something feel “sweet” or “bitter” is not simply the receptor itself, but the specific neural pathway activated between the tongue and the brain. By defining how chemical signals on the tongue are translated into perception and behavior, Zuker transformed taste from one of the least understood sensory systems into one of the best mapped in modern neuroscience. Congratulations to Charles S. Zuker, 2026 Wolf Prize Laureate in Medicine.
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Congrats!
Thrilled to be one of the 25 winners for the @NIH #TRDNT Challenge (Phase 1). 🏆 🏆🏆We will develop an all-in-one #RNA trans-splicing platform for highly efficient and programmable exon editing. We hope to expand the list of druggable target genes that are challenging with current technologies. Kudos to the leading postdoc in the lab Ye Wang for what we have achieved so far! I am very excited about what to expect moving forward! @ColumbiaSysBio @ColumbiaPS @Columbia #RNA #PrecisionMedicine nih.gov/challenges/targeting…
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Natalie Fardian-Melamed was named a Blavatnik Regional Award for Young Scientists laureate. Samuel H. Sternberg was named a finalist for the Blavatnik National Awards for Young Scientists. news.columbia.edu/news/colum…
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LomvardasLab retweeted
Excited to share our new preprint! 🎉 Using base-editor screens, we reveal how individual residues within the intrinsically disordered region of YTHDF2 control protein interactions, condensate recruitment, and m⁶A-dependent mRNA decay. biorxiv.org/content/10.64898… 🧵👇
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We’re expanding! The Concepcion Lab at @ColumbiaPS @columbiacancer is searching for a Postdoctoral Research Scientist to study epigenetic deregulation & chromatin states in lung cancer. 🧬🔬 Pls share! academic.careers.columbia.ed…
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LomvardasLab retweeted
📢 Our Dept. of Systems Biology @Columbia has a faculty opening in the broad area of quantitative biology (Comp/AI/Bio, etc.). Come join our department in NYC! Please circulate/RT. Apply: apply.interfolio.com/192256 Deadline: Nov 1, 2026. @ColumbiaSysBio systemsbiology.columbia.edu/…
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Happy to share molecular mechanics of AMPA-subtype ionotropic glutamate receptor (iGluR) pre-activation and complete gating pathway revealed by time-resolved cryo-EM with the help of full and partial agonists. @MariaKarela3 @MKCMU @shantigangwar nature.com/articles/s41594-0…
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Welcome aboard- we are so lucky to have you!
I'm thrilled to share that I'll join Columbia University in Jan 2027 as an Assistant Professor in @ColumbiaGenDev & @CSCIColumbia ! A long-held dream; I'm grateful for my mentors and colleagues. We'll study microbiota-ENS interactions & we’re hiring! theaydinlab.com/?ref=1
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Our back to back paper @NatureNeuro is out today (rdcu.be/fzGg0). We developed a method to visualize ribosomes bound to endogenous mRNAs with near codon resolution and made some really counterintuitive cell biological discoveries which have cool implications for AD🧵
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Coordinated RNA- and protein-templated synthesis of double-stranded DNA by a dual reverse transcriptase immune system: Cell cell.com/cell/fulltext/S0092… Another breakthrough from @SternbergLab reminds us how little we know about molecular biology...
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