Hibbert Professor of Bioengineering @pennbioeng | Lipid Nanoparticles | mRNA Therapeutics & Vaccines | Drug Delivery | Biomaterials | Immunotherapy

University of Pennsylvania
Joined August 2011
Mike Mitchell retweeted
Young Innovators Session I was a success, featuring great work from Brian Aguado, Ana M. Porras, Ryan Stowers, Kuei-Chun Wang, Karin Wang, and Jouha Min. Thanks to session chairs Priscilla Hwang and Matthew Lazzara! #BMES2026, @BMESociety Read it here: link.springer.com/journal/12…
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Mike Mitchell retweeted
Young Innovator, Karin Wang @templebioe , will present “Tumor-Associated Fibroblast-Derived Matrix Containing EDA-FN Alters Macrophage Behavior” on 10/23 at 3:00 PM in Crystal M. #BMES2026 @BMESociety The full paper will appear here soon: link.springer.com/collection…
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Mike Mitchell retweeted
Daeyeon Lee has received the 2026–27 George H. Heilmeier Faculty Award for Excellence in Research for his advances in understanding and exploiting interfacial phenomena in soft matter and biomaterials. Lee is the Russell Pearce and Elizabeth Crimian Heuer Professor in @CBE_Penn. The Heilmeier Lecture will take place in Spring 2027. bit.ly/3TUvf4D
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Mike Mitchell retweeted
Join us as we welcome Claudia Loebel to our next episode of #TissueTalks as she discusses, "Mapping the Nascent Extracellular Matrix in Tissue Remodeling and Repair" Register now👉 columbiauniversity.zoom.us/w…
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Mike Mitchell retweeted
Super exited to share our latest review in Chem led by Dr. Bowen Wu and Dr. Xuehe Lu in collaboration with @MJMitchell_Lab on discussing synthesis and optimization of ionizable lipids for RNA delivery! Free access: authors.elsevier.com/a/1nqbf…
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Mike Mitchell retweeted
We’re hiring. The Department of Bioengineering is seeking faculty at the Assistant, Associate and Full Professor levels across bioengineering as part of a multi-year hiring initiative. Applications due Nov. 23, 2026. Learn more + apply: be.engineering.upenn.edu/abo… @PennEngineers
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Mike Mitchell retweeted
Thrilled to share our Fanzor2 genome-editing work @NatureBiotech! We developed FanzMAX, a compact genome editor, by combining AI-assisted protein evolution, ωRNA engineering, and in vivo delivery. Huge thanks to all co-authors, and collaborators for making this work possible!
Adaptive model-guided protein evolution with sparse data optimizes compact eukaryotic genome editors - @XueSherryGao nature.com/articles/s41587-0…
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Mike Mitchell retweeted
Penn researchers have built the first spatial map of the developing human kidney, analyzing more than 700,000 cells to show how soluble signals from neighboring cells guide development. The study was conducted by the Penn-CHOP Kidney Innovation Center, a collaboration between @PennMedicine and @ChildrensPhila, in partnership with Penn Engineering and the @IRM_UPenn. "The kidney is a physical structure, and physical context is not incidental to how it forms—it is instructive," says Alex J. Hughes, Associate Professor in @PennBioeng, who co-led the study. bit.ly/4hrJYgO
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Mike Mitchell retweeted
Argentina = Knicks
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Mike Mitchell retweeted
The last dance continues for Leo 🐐
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🏆 #FIFAWorldCup ⚽ #Argentina 2 (Enzo Fernández y Lautaro Martínez) 🆚 #Inglaterra 🏴󠁧󠁢󠁥󠁮󠁧󠁿 1 (Anthony Gordon) 👉 ¡Final del partido! 🔥 Imposible no ilusionarse... ¡vamos, un pasito más!
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Mike Mitchell retweeted
ARGENTINA STORM BACK TO ELIMINATE ENGLAND AND RETURN TO THE WORLD CUP FINAL 🇦🇷🔥
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Mike Mitchell retweeted
Legendary. 📸: Elsa/Getty Images
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Mike Mitchell retweeted
Messi has ended the GOAT conversation.
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🏆 #FIFAWorldCup ⚽ #Argentina 3 (Cristian Romero, Lionel #Messi y Enzo Fernández) 🆚 #Egipto 🇪🇬 2 (Yasser Ibrahim y Mostafa Ziko) 👉 ¡Final del partido! 🔥 Imposible no ilusionarse... 👋 ¡Nos vemos en cuartos de final!
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Mike Mitchell retweeted
ARGENTINA COMPLETE THE COMEBACK AGAINST EGYPT AND ADVANCE TO THE WORLD CUP QUARTERFINALS 🍿🍿🍿
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Mike Mitchell retweeted
CAN YOU BELIEVE THIS! ARGENTINA ONCE DOWN 0-2 HAVE TURNED IT ALL AROUND TO GO UP 3-2! THE REIGNING WORLD CUP CHAMPIONS HAVE COMEBACK WHEN IT MATTERED MOST!
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Mike Mitchell retweeted
Cuba: As of 12 p.m. ET, Cuba experienced a total power failure due to a collapse of Cuba’s electrical grid.  According to Cuban regime media, the reason for the collapse and the timeline to restore power is unknown. All U.S. citizens in Cuba or planning to travel to Cuba should be aware and plan accordingly. There are reports of cellphone and internet outages. Read the full alert for more information: cu.usembassy.gov/security-al…
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Mike Mitchell retweeted
Excited to share our latest work, now published in @NatureBiotech! We established the first prime editing platform for filamentous fungi, achieving average editing efficiencies approaching 90% across diverse loci and species. nature.com/articles/s41587-0…
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Mike Mitchell retweeted
here is Mamdani's entire speech at the Knicks parade, which is easily the best speech I've ever heard at an event of this sort
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