The Mallikaratchy lab uses programmable molecular tools based on nucleic acid aptamers (NAAs) to understand the fundamentals of bio-molecular interactions.
New York, NY
Joined January 2019
- Tweets200
- Following229
- Followers386
- Likes1.3K
Prabodhika Mallikaratchy retweeted
BREAKING NEWS
The 2026 #NobelPrize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.”
@EVydaline thesis project is live on BioRxiv! Aptamers against native-state β2AR using an advanced LIGS variant. Proud of Vydaline and the whole lab! Grateful to@NIGMS_NIH for supporting this work and the G-RISE and U-RISE training grants.@CUNYMed @GC_BiochemPhD @GC_CUNY @CUNY
Prabodhika Mallikaratchy retweeted
Join us for the @ClinicPharmSTL Research Seminar featuring Dr. Prabodhika Mallikaratchy from @CUNYMed @MalikaratchyLab
Details ⬇️
📆 Wednesday, April 23
⏰ 1-2 p.m.
📍 UHSP Academic and Research Building room 222
sites.wustl.edu/centerforcli…
Congratulations to Dr Vydaline Agbor Otu on her excellent PhD defense! She spearheaded and successfully completed a difficult project while also managing the challenges of raising a family. An incredible achievement and a true testament to her dedication and perseverance!🎉🎉🎉
And last but not least—our 3rd Fall publication 🎉 A study from a new branch of our lab exploring modified nucleic acids, their functions, and applications, led by our amazing team of students & postdocs!@SURESHLINGALA13 @CUNY @CUNYMed 🔬👏 | ACS Omega pubs.acs.org/doi/full/10.102…
Our 2nd publication this Fall explores the function of CD19/CD20 aptamers generated by LIGS 🔬 Led by our talented student Yilam... @CUNY @GC_CUNY @CUNYMed
cell.com/molecular-therapy-f…
Excited to share 3 publications from our lab this Fall! 🎉
First up: a comprehensive review on aptamers ad delivery agents, led by our talented students Vydaline, Sergei, and German 👏
@GC_CUNY @CUNYMed @EVydaline
sciencedirect.com/science/ar…
Prabodhika Mallikaratchy retweeted
A US Senate committee endorsed maintaining the NIH's structure and increasing its funding by US$400 million, or about 1%
go.nature.com/45gJzGf
Prabodhika Mallikaratchy retweeted
On the cover of this week's issue: "Chirality-Promoted Chemical Ligation and Reverse Transcription of Acyclic Threoninol Nucleic Acid"
Read it here 🔗 go.acs.org/cFJ
Prabodhika Mallikaratchy retweeted
Very happy that the long, long, long, long, long overdue day when the published results of all @NIH funded research is immediately freely available to everyone who can benefit from it. Kudos to the @NIH for making this happen, and eternal curses to the scientific societies, publishers and research 'leaders' who spent 30 years wielding their influence to block this, for the immeasurable harm to scientific progress and public trust in science they have wrought.
NIH Director Dr. Jay Bhattacharya has announced that the NIH Public Access Policy, originally slated to go into effect on 12/31/25 will now be effective 7/1/25. Read more in his statement: bit.ly/4jTQI4O
ALT Graphic with blue background, HHS and NIH logo, and a photo of NIH Director Dr. Jay Bhattacharya. Quote included: "Providing speedy public access to NIH-funded results is just one of the ways we are working to earn back the trust of the American people. Trust in science is an essential element in Making America Healthy Again. As such, NIH and its research partners will continue to promote maximum transparency in all that we do."
We are excited to share our preprint, which was led by the incredibly talented student, Yilam Ng Cen.
The biochemical function of bivalent aptamer assemblies against B-cell markers CD19 and CD20 biorxiv.org/content/10.1101/…
Additionally, we uncovered new biochemical insights into the duplex’s promiscuity toward DNase I and two restriction enzymes, which might be governed by observed conformation switch. @DNAnanoscience @WONDER_DNA
This is just the first of several studies in this direction from our lab—stay tuned for more exciting work! Huge thanks to our super fantastic team for making this possible! @SURESHLINGALA13 @MohanraoRaja @CUNYMed @CUNY @GC_CUNY @biorxivpreprint
Prabodhika Mallikaratchy retweeted
.@CUNYMed was awarded $19.3 million from @NIH to create a health equity center that will address health disparities through scientific research and outreach in Harlem and the South Bronx. cuny.edu/news/cuny-school-of…
