You always fear getting screenshotted, but this one I'm quite proud of

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I am officially free from SSRIs. I was put on them as a young teenager, just starting my life out. Like many people in my generation, I was on them for more than a decade. I successfully tapered from 125mg to nothing. No more zoloft.

since i brushed my teeth this morning: - Capcom has been hacked, 12 million personal address leaked. - Major US banks reported unauthorized ai agent activity executing unapproved actions - leading medical provider Quest Diagnostics has been hacked, personal data leaked. - multiple foreign governments have shut down crucial national systems due to PHP exploit. i don’t care what you think - this is unprecedented armageddon spreading at lightning speed with the potential to snowball into a catastrophe. wtf is going on?

All of this is true, but it's important to note that we can cause fatty liver in humans without any sugar at all. Sugar makes it worse, but does not cause it.

Another way to explain why AI won’t be curing all disease soon is that it doesn’t remove the bottleneck. No, it’s not that it won’t be smart enough. Hell, it’s smart enough now, let alone in a year or 5 years. But no matter how smart it is, it just moves the bottleneck downstream. The perfect virtual cell and virtual tissue and virtual human will generate hypotheses, insanely good hypotheses that we’d never come up with on our own. Then AI will design the experiments to validate the hypotheses and run them in parallel and that’ll get us incredible drugs. But once we have the drugs we won’t know if they’re cures until we give them to real, live humans and watch them for the rest of their lives. So amazing treatments, which we already have, are going to start dropping faster than Millennium Prize problems. (I actually heard Anthropic is dropping 816 drug candidates the weekend before their IPO, BTW. You heard it here first.) But the point is that you can check a math proof by reading it. To check a cure you have to observe lots of humans for their entire lives. So how long does it take to find out if a treatment is a cure? An entire human lifespan. That’s the bottleneck. @AlexanderKalian

Ethan Hawke Admits He Wishes He Had Dated Drew Barrymore After Revealing He Used To Hope He’d Run Into Her At Parties In The ’90s Ethan Hawke: “I don’t think I can remember a time in my life when I was not aware of you.” Drew Barrymore: “What me and every other girl on the planet wouldn’t have given to date you. Where the hell were you?” Ethan Hawke: “There were many a night in the ’90s when I’d be going to a party and think, ‘Maybe Drew will be there.’” Drew Barrymore: “Why didn’t you call me? We still had phones back then!” Ethan Hawke: “I wanted it to happen organically. I thought something magical would happen.” Drew Barrymore: “And look what happened: nothing!”

This is seriously hilarious to me because my wife will literally say “only 8 hours” lol