Maiken Nedergaard lab members tweeting from CTN at the University of Copenhagen, Denmark. All about Astrocytes, Glymphatics, Ions, and Sleep.
University of Copenhagen
Joined March 2023
- Tweets141
- Following57
- Followers1.5K
- Likes79
NedergaardLab retweeted
Vittani, Lee, Wang, Hiraoka, et al.
KI mouse expressing red fluorescent blood
In situ SpyTag/Catcher attachment of biosensor
ECS SpyCatcher to capture BBB leak
doi.org/10.1101/2025.03.18.6…
We hope this method is useful to a wide range of the biology community.
NedergaardLab retweeted
Out today in @CellCellPress !
We show that oscillations in norepinephrine and cerebral blood volume are the missing pieces that link NREM sleep to clearance of waste from the brain 🧠💤 cell.com/cell/fulltext/S0092…
NedergaardLab retweeted
12 Months of #Neuroscience
March 2024
We can now see oxygen in the brain! It is already providing insight into why a sedentary lifestyle risk for diseases like #Alzheimers this #URochesterResearch method via @NedergaardLab made the discovery using a protein similar to what gives a firefly its glow.
@ScienceMagazine 👉 science.org/doi/10.1126/scie…
NedergaardLab retweeted
How can understanding brain waste flow inform brain health?
Prof Douglas Kelley, PhD, of Mechanical Engineering @UofR Hajim, aims to understand the glymphatic system so conditions like #Alzheimer's and #Parkinson's can be studied more effectively. #URochesterResearch In a Neuro Minute🧠
NedergaardLab retweeted
1/4 We are thrilled to announce that our 🌍 collaboration has resulted in a paper in @_JCBFM. @Gazz4_Science @CathFoster_ @BradASutherland @UTAS_ @SeattleChildrens @uni_copenhagen
doi.org/10.1177/0271678X2412…
NedergaardLab retweeted
Virally Induced CRISPR/Cas9-Based Knock-In of Fluorescent Albumin Allows Long-Term Visualization of Cerebral Circulation in Infant and Adult Mice
link.springer.com/protocol/1…|
Marta Vittani, Philip Aleksander Gade Knak, Masahiro Fukuda, Masaki Nagao, Xiaowen Wang, et al.
NedergaardLab retweeted
2 years of postdoctoral fellowship in Translational Neuroscience completed today. Grateful for the opportunity @UCPH_BRIDGE & @novonordiskfond. I thank my excellent mentors, Prof. @MaiNedergaard & Prof. @MessoudAshina @NedergaardLab @hmru_cph @UCPH_health #migraine
NedergaardLab retweeted
Oxygen sensor for in vivo expression available now on Addgene: AAV vector expressing GFAP-GeNL addgene.org/221455/ @NedergaardLab
NedergaardLab retweeted
Online now! Cervical lymphatics drain CSF and clear metabolic waste from the brain. Du et al., show using 2P-OPTIC that these are disrupted in aging due to reduced pumping. Restoring cervical lymphatic function with PGF2a rescues brain clearance. doi.org/10.1038/s43587-024-0…
NedergaardLab retweeted
Beautiful paper from @NedergaardLab in @NatureAging on the role of cervical lymphatics in cleansing of aged brain. Glymphatics/meningeal lymphatics = bff 🤩|| nature.com/articles/s43587-0…
NedergaardLab retweeted
#URochesterResearch via @NatureAging shows how
scientists restored the brain’s ability to clear toxic waste in older mice with a drug that's currently used to induce labor. This points to a potential new treatment for #Alzheimers and #Parkinsons.
Paper: go.nature.com/46WCR8F
👇Watch the aging lymphatic system – less contractions in the older mouse (right) causing the waste to stop and flow in different directions.
NedergaardLab retweeted
Our latest paper from the Lilius lab is now out in @_Anesthesiology!
doi.org/10.1097/ALN.00000000…
I'm happy to have been able to co-first author this paper together with @LohelaT under the supervision of @tlilius!
In collaboration with people from the @NedergaardLab
NedergaardLab retweeted
A new Science study in mice identifies a novel non-synaptic signaling mechanism between the brain and peripheral sensory system important for migraine.
Learn more ⬇️
📄: scim.ag/7D5
#SciencePerspective: scim.ag/7D4
NedergaardLab retweeted
🏖️ Summer vacations are perfect for catching up on sleep! 💤
Discover why sleep is crucial for our brains through Maiken Nedergaard's pioneering work on the glymphatic system. Watch her fascinating #HFSPNakasone lecture: youtu.be/f7IcZag6loY #SleepScience @NedergaardLab
NedergaardLab retweeted
Years ago Martin Rasmussen was on a Fulbright studying meningeal afferents in my lab & noticed dyes placed in CSF accumulate in trigeminal ganglia. This observation nucleated his PhD project in @NedergaardLab & has now led to a new model of migraine pain. science.org/doi/10.1126/scie…
NedergaardLab retweeted
For millennia, migraine's origin puzzled scientists. We contributed to the @ScienceMagazine paper showing how cortical spreading depression alters 11% of CSF proteome, including 2-fold increase in CGRP. The proteomic shift may explain aura-headache link. @nicwin98 @NedergaardLab
Cerebrospinal fluid links the brain and peripheral sensory system and drives headache in migraine with aura! We’re excited to share our newest article just published today in @ScienceMagazine . Please read along:
science.org/doi/10.1126/scie…
NedergaardLab retweeted
Follow the fluid: new #URochesterResearch from
@NedergaardLab sheds light on connection between auras and migraines, points to new drug targets.
Via @ScienceMagazine👉urmc.info/1DD urmc.info/1DE
NedergaardLab retweeted
Visit our poster 09-221:
Three new plasma labeling approaches using liver-secreted fluorescent albumin for chronic imaging of the microcirculation
International Vascular Biology Meeting / Amsterdam
Marta Vittani will be explaining tomorrow, 3/July #ivbm2024 @NedergaardLab
NedergaardLab retweeted
Back from the Glymphatic symposium in Lund #LGS2024 feeling super inspired. Thank you for putting it all together @Iben_Lundgaard #Glymphatics.
NedergaardLab retweeted
Had an amazing time @karolinskainst last week, joining the symposium on Astrocytes in Brain Function and Disease. Big thanks to the organizers @CheongEunji Justin C Lee, Angeta Nordberg, Alex Verkhratsky and KNTEC! Thanks for having me!
