Proud father and husband. Twin. Doctor. Adv. GI/Minimally Invasive and Bariatric Surgeon. Opinions are my own. @CCF_Alumni

Weston, FL
Joined August 2010
Paul J. Perales, MD retweeted
We are saddened by the passing of Rachna T. Shroff, MD, MS, a renowned physician-scientist who treated people with pancreatic cancer and advanced treatment options for patients facing pancreatic and hepatobiliary cancers. Dr. Shroff passed away following a battle with an aggressive cancer. She was 47. Through her groundbreaking research and leadership in clinical trials, Dr. Shroff helped move the field forward and expand possibilities for patients. She also collaborated with PanCAN on research related to our Know Your Tumor® precision medicine service, contributing to a deeper understanding of pancreatic cancer. We extend our heartfelt condolences to her loved ones, colleagues and the many patients whose lives she touched. 💜 Read more from the @UAZMedTucson at 🔗 bit.ly/4jprjTS.
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Paul J. Perales, MD retweeted
Pope Leo XIV celebrated Mass at noon on Friday in the room set up on the 10th floor of Gemelli Hospital, according to the Holy See Press Office. Several members of Gemelli's medical and nursing staff attended the Mass, along with members of the Vatican City State Gendarmerie Corps. "In his homily, the Pope thanked all the staff—doctors, nurses, and orderlies—for the work they do every day caring for patients in their frailty, and especially for what they have done and continue to do for him," read the statement.
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Paul J. Perales, MD retweeted
Her life was way too short. But she impacted people a lot. Thanks 🙏 @rachnatshroff
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Paul J. Perales, MD retweeted
“It’s been a journey” Shroff told @NBCNews. “I’ve spent my entire life trying to eradicate cancer, primarily pancreatic cancer, but also liver cancers.” nbcnews.com/health/disease/r… An homage to Rachna Shroff, including thoughts from her family. Please read, share & honor her memory.
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Paul J. Perales, MD retweeted
Pope Leo XIV underwent thoracic surgery at Gemelli Hospital on Tuesday afternoon, as planned, according to a statement from Dr. Luigi Carbone and Professor Stefano Margaritora released by the Holy See Press Office. The surgeons removed the lower lobe of the Pope’s right lung, and tissue examined during the operation confirmed the diagnosis of “lung adenocarcinoma,” as suspected from tests conducted beforehand. The Pope was in the operating room approximately three hours, while the operation itself lasted about 90 minutes. The doctors said it was successful and there were no complications. Pope Leo awoke normally after surgery and, following a brief period of observation, returned to his room on the hospital’s 10th floor, according to the statement. vaticannews.va/en/pope/news/…
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Paul J. Perales, MD retweeted
Dear friends, during some recent medical examinations, the doctors found a small, localized nodule in my lung. It was detected at a very early stage and is well-localized. The doctors believe that it is best to intervene, so, following their advice, I have decided to undergo surgery to remove it. The operation is already scheduled to take place in the coming days. I thank you for your spiritual closeness and entrust myself to your prayers.
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Paul J. Perales, MD retweeted
ATOMIC Trial for dMMR colon cancer. 👇🏼👇🏼
FDA approves new treatment option, #atezolizumab in combination with chemotherapy, for patients with stage III dMMR #coloncancer based on results from the phase III #ATOMIC trial led by @ALLIANCE_org. Learn more: bit.ly/FDA-ATOMIC @theNCI #NCTN #CancerResearch #CRCsm
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Paul J. Perales, MD retweeted
Congrats to my good friend and AMAZING leader and person @SyedAAhmad5 🙌. @waynestate @waynemedicine is so lucky that you are joining them!! Excited to see the department of surgery soar 🚀 with you at helm. #congrats 🎉
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Paul J. Perales, MD retweeted
BREAKING: The Nobel Prize in Physiology or Medicine has been awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel “for their discoveries concerning light-gated ion channels and optogenetics.” More to follow.
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Paul J. Perales, MD retweeted
Where patients receive cancer care matters. In our new @JSurgResearch study of 47,783 stage III/IV melanoma pts, care at high-volume immunotherapy hospitals was associated with greater immunotherapy use, higher survival (adjusted HR 0.83), and fewer observed racial disparities.
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Paul J. Perales, MD retweeted
CLDN18.2 is expressed in 23% of primary PDAC tumours, indicating its potential to be used as a therapeutic target in a significant proportion of PDAC patients, and its expression is associated with improved OS in resected PDAC,supporting its role as a prognostic factor. 👇🏼👇🏼
Featured: Prognostic Value of Intratumoral Expression of Claudin 18.2 in Resected #PancreaticCancer @OskarFranklin ow.ly/wpHX50ZQlwh @younghong522 @SocSurgOnc
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Paul J. Perales, MD retweeted
What is the optimal surgical approach for adenocarcinoma of the oesophagogastric junction? Zheng et al. present “Prospective evaluation of radical surgery for adenocarcinoma of oesophagogastric junction: real-world insights from the CLAEG study” via bit.ly/4j59Xv6 Drawing on the large prospective CLAEG registry across 44 high-volume centres and more than 2,000 radical resections, this study provides valuable real-world data on lymph-node metastasis patterns and surgical outcomes. The analysis helps clarify where metastatic lymph nodes are most commonly found and examines important questions around the extent and type of surgery. The findings provide practical evidence to inform surgical decision-making for this increasingly important and challenging cancer. #OGCancer #GastricCancer
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September Issue: Impact of Muscle Mass Loss on Survival During Neoadjuvant Chemoradiotherapy in Patients with Locally Advanced #EsophagealSquamousCellCarcinoma : A Multi-center Retrospective Study in China (TIMES Study) ow.ly/ctBh50ZQhoA @AndrewFlemingMD @SocSurgOnc
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Paul J. Perales, MD retweeted
It’s likely that more than 1 million patients have benefited from immunotherapy since 2011. But immunotherapy is not yet curing every patient. The James P. Allison Institute™ is committed to bringing the benefits to all patients: spr.ly/6013BGbWR7 #EndCancer
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Paul J. Perales, MD retweeted
29 years ago today Oasis released Stand By Me ✨️
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Paul J. Perales, MD retweeted
📝 #JAMAReview: #Cancer vaccines are being evaluated for treatment and prevention across multiple malignant neoplasms as advances in tumor immunology, antigen discovery, and vaccine delivery reshape the field. This Review discusses how vaccines can stimulate adaptive immunity against neoantigens, nonmutated tumor proteins, or tumor-derived antigens, with current approved uses in melanoma, prostate cancer, and bladder cancer. 🔗 ja.ma/4hBPEEu
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Paul J. Perales, MD retweeted
I will lead a workshop on Surgeon Identity at the 2026 @WomenSurgeons Annual Conference in Washington, DC, on September 25–26. We’ll explore how we define ourselves as surgeons and how we wish to show up. womensurgeons.org/annual-con… #AWS2026
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#AudioVisualAbstract : Decision Regret and Burden in Caregivers of Patients with #AppendicealCancer Undergoing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy ( #CRSHIPEC ). @AlissaGreenbaum ow.ly/tEWq50ZORij @DrPandalai @SyedAAhmad5
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