Associate Professor @ResearchUGent @UGent_HSR @microscopyUGent 'FLIM gypsy' and developer of #FLIM #PLIM bio-/nanosensors for #organoids #3D PI @FlImagin3_DN
Ghent University, Belgium
Joined January 2010
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#NewPaperAlert now we have this study published in @angew_chem Proud to be involved in such an interesting study shedding a new light on design of solvatochromic and hydration-sensing fluorescent dyes! This new generation of #BODIPY dyes offers everything that [1/3]
#Preprint alert! Together with Filatov's group (TUD), we report a new type of O-BODIPY dyes displaying exceptional brightness & fluorescence lifetime range sensitive to... water! chemrxiv.org/doi/full/10.264… works great in #FLIM with cells, spheroids & organoids! @microscopyUGent
Ruslan Dmitriev retweeted
How we are approaching AI at openRxiv - new blog post prompted by growing adoption by researchers, submission patterns, and questions from the community. 1/n
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Join the Committee on Sustainability of the Biophysical Society for a Webinar on Sustainable Computing in Biophysics!
Wednesday, October 21, 12:00 PM - 1:30 PM ET
Register now
buff.ly/uRIqeXP
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Don't miss this organoid symposium in Utrecht, NL! January 19-21 2027
organoids-are-us.com/
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This a cinema in Göktürk, Turkey after the extreme rain.
Ironic considering that Hollywood has barely engaged with the climate Crisis, in the weeks after one of the biggest films to ever do so, Digger, was savaged by critics.
Biz Göktürk’ün sinemasıyız…
Burada yalnızca film göstermiyoruz. Çocukların ilk sinema heyecanına, ailelerin birlikte geçirdiği güzel saatlere, komşularımızın anılarına ev sahipliği yapıyoruz.
Artan maliyetlere ve enflasyona rağmen ayakta kalmaya, hizmet kalitemizi korumaya ve sizlere en iyisini sunmaya çalışırken, sinemamız bir kez daha su altında kaldı.
Bu görüntülerde bizim emeğimiz, geçim kaynağımız ve büyük çabalarla yaşatmaya çalıştığımız sinemamız var. Yaşadığımız hasarın yanında, kapalı kaldığımız her gün kaybımız da büyüyor.
Yeniden toparlanmak, kapılarımızı açmak ve sizleri ağırlamak istiyoruz. Ancak üst üste yaşadığımız bu mağduriyet bizi hem maddi hem manevi olarak çok zorluyor.
Bu süreçte mağdur olan tüm komşularımıza da geçmiş olsun dileklerimizi iletiyor, benzer bir durumun bir daha yaşanmamasını temenni ediyoruz.
Göktürk’ün duyarlı komşularına sesleniyoruz: Yaşadıklarımızın duyulmasına destek olmanız, bu paylaşımı yaymanız ve yeniden açıldığımızda bizi tercih etmeniz bizim için çok kıymetli.
Dileğimiz, bu soruna kalıcı bir çözüm bulunması ve emeklerimizin yeniden sular altında kalmaması.
Göktürk’te sinemanın ışığını birlikte yaşatalım.
Cineport Sinemaları
Göktürk’ün sineması.
#göktürk #kemerburgaz #afet
hey is anybody going? Our team has submitted 2 abstracts (one on FLIM-FRET O2 sensing and another one about FLIM-based metabolic atlas of cell types in intestinal organoids), - depending on the success with travel grants, we may attend or not.
3️⃣ days left to submit your abstract for #bps2027! Present your research at the BPS Annual Meeting in Philadelphia buff.ly/VqqKII9
Ruslan Dmitriev retweeted
Few scientists have inspired generations quite like John Condeelis. Join us Oct. 22 to celebrate his 48 years at @EinsteinMed, his pioneering cancer imaging research, and the community he built. Live at 1 p.m. ET:
tinyurl.com/CondeelisSymposi…
#CancerResearch
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May I suggest we all read this?
Evidence based
Frightening
Action needed right now.
The report estimates that limiting warming to approximately 1.8°C rather than 4.4°C could prevent 1.89 billion disability-adjusted life years (DALYs) being lost by 2100.
The deadline has been extended until 28 October! If you haven't had a chance to submit your abstract yet, you still can do it :)
Excited to speak about #FLIM & #organoids at the conference on new approaches #NAM for 3D cell culture in Freiburg 16-18 March 2027 organised @DECHEMA A lot of cool keynote speakers already: dechema.de/en/3DCC2027
[2/3] real #FLIM researcher can wish for: extremely broad range of lifetimes, QY and staining ability, which I think is unmatched (or very close to be) by any other dye structures used in live #FLIM of #spheroids #organoids. As a bonus, it also works excellently for
[3/3] one-dye labelling of multiple intracellular organelles, see example with 5-TEG below. Really excited to continue with more in-depth biological evaluation of these dyes. Enjoy reading the paper here doi.org/10.1002/anie.3726851
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#lipidtime: It's a lipid universe. Today in Nature we publish the Lipid Brain Atlas, the first map of membrane lipid composition across the entire mouse brain, a layer of organisation that cell-type and transcript maps had left out. #lipidomics #neuroscience #BrainAtlas
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Published in #AngewandteChemieNovit: A Review on Machine Learning for Synthetic Organic Chemistry: Methods, Applications, and Best Practices by Frank Glorius and co-workers. Read it here: onlinelibrary.wiley.com/doi/…
Second edition of #IntestinalStemCells @organoidscience is out! Edited by @OrdonezMoranLab it again combines a great compendium of experimental protocols and techniques enabling advanced studies of #organoids #coloncancer and more! link.springer.com/book/10.10…
My team is proud to contribute with 2 protocols, using advanced microscopy #FLIM & #organoids: combining cell proliferation imaging with NADPH-FLIM and FRET-FLIM-based Ca2+ activity: link.springer.com/protocol/1… & link.springer.com/protocol/1…
#Preprint alert! Together with Filatov's group (TUD), we report a new type of O-BODIPY dyes displaying exceptional brightness & fluorescence lifetime range sensitive to... water! chemrxiv.org/doi/full/10.264… works great in #FLIM with cells, spheroids & organoids! @microscopyUGent
Great news for #FluorescenceFriday (although I read email on Saturday morning), this manuscript has been accepted! Hope it will be published shortly. Stay tuned :)
Ruslan Dmitriev retweeted
Today in @Nature, we report a new approach to studying human brain development and modeling disease in vivo.
Human neural #assembloids and #organoids have opened new ways to study development in vitro, but they also have important limitations. Transplantation can provide a more physiological environment, yet human cortical cells then develop within a rodent brain that matures much faster, constraining their growth and integration.
To address some of these limitations and obtain more advanced functional readouts relevant to disease biology, we generated #apallial mice, in which ~98% of the cortex and hippocampus fail to form, creating space for transplanted human cortical organoids to grow and integrate extensively.
We call these #xenocortical mice (XCX).
Nearly 7 years in the making. Congratulations to an extraordinary team and wonderful collaborators!
Link to the article below 👇
He really has, we tested and it works :)
We have a solution for this if colleagues send me a message I can start sharing a testing release. #FLIM file export interrogator
Ruslan Dmitriev retweeted
We have a solution for this if colleagues send me a message I can start sharing a testing release. #FLIM file export interrogator
Anyone found a quick way to open #Leica FLIM images from the Falcon outside of LAS X? We need to manipulate the raw data for many of our projects! We have the Picoquant export but that is way to slow for hundreds of files!