Our own opinions 🔬👩🏻🔬🐭 👨🔬👩🏻💻📚#sphingolipids #metabolism #signaling #genetics #LysosomalStorageDisease #neurodegeneration #MouseModels
Bethesda, MD
Joined January 2018
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Proia Lab retweeted
Do microglia and/or neurons contribute to Gaucher disease? insight.jci.org/articles/vie…
Hannah Duffy, Colleen Byrnes, et al. use cell-specific deletion models to answer the question.
Image: specificity of the Gba deletion in microglia (left) and neurons (right).
@ProiaLab @NIDDKgov
#NationalDNADay commemorates the completion of the Human Genome Project in 2003 and the discovery of the double-helical structure of DNA in 1953. 📸 #TheLadder @ NIH campus
Proia Lab retweeted
Sialidase NEU3 action on GM1 ganglioside is neuroprotective in GM1 Gangliosidosis buff.ly/3QJQvFT (@jlipidres)
Proia Lab retweeted
🔬#LRMSRC is an unmissable opportunity to discuss the biology of lysophospholipids.
Join us, share your research and learn from the world experts in the field @hlatim @ar_dilorenzo @ProiaLab @CChristoffer78
web.cvent.com/event/6c972c32…
#Lysophospholipids #FASEBconferences – at Melbourne, FL
SARS-CoV-2 can harm the brain. Our study found ORF3a, a key protein of the virus, led to COVID-19 neuropathological features in mouse brains. ORF3a disrupted autophagy-lysosomal pathway & caused neuronal accumulation of factors linked to neurodegenerative disease. #sphingolipids