@Proteopathy_Lab

A translational&interdisciplinary research center at @McGovernMed developing novel diagnostic tools & therapeutics for protein-misfolding-diseases

 Neurology, UTHealth, Houston
med.uth.edu/neurology/specialty-programs/mitchell-center/soto-lab/
Joined March 2021
  • Tweets63
  • Following1.1K
  • Followers209
4Media
We are #HIRINGNOW #postdocs with #Biochemistry #biophysics experience! Project involves #stemcells #singlecell #multiomics #CryoEM for #Parkinsons #research. DM for more info or use link below: linkedin.com/posts/mitchell-… #Parkinson #tau #STEM #postdocjobs #protein
Mitchell Center for AD (Claudio Soto Lab) retweeted
anette schrag@a_schrag6 Jan 2022
Just out in @TheLancetNeuro — our review of neuropsychiatric features of #Parkinsons @movedisorder @UCLMentalHealth @UCLBrainScience @MDC_IoN_UCL thelancet.com/journals/laneu…
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We had a #Christmas event after two years!! Fabulous Brazilian Steakhouse lunch at Casa do Brazil! #MerryChristmas to everyone and #HappyHolidays! Stay Safe everyone! #AcademicTwitter #Christmas2021 #biology
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Mitchell Center for AD (Claudio Soto Lab) retweeted
Ventura's Lab@PPMC_UAB8 Dec 2021
Together with @AnoopArunagiri and other colleagues we launch frontiersin.org/research-top… Looking forward for your contributions on multiple flavors of #Protein_homeostasis; #Protein_aggregates; #Phase_separation; #Protein_condensates; #Amyloids and #Proteotoxicity among others!

Molecular Determinants of Protein Assemblies in Health and Disease

Proteins/peptides can self-assemble to form supramolecular entities called “aggregates”. Protein aggregation is a phenomenon that can be both directed and inadvertent; the latter is often proceeded...

frontiersin.org
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We are hiring two #postdoc! R you looking to lead exciting projects using #stemcell/#organoids/#chimeric mice models of #neurodegeneration?We would love to hear from you! Please use link below for more details: linkedin.com/jobs/view/28173… #postdocjobs #Parkinsons #AlzheimersDisease
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@WorkAcademic @PostdocJobs @PostDocsForum @PhDVoice @PostDocVoices #STEMeducation
Mitchell Center for AD (Claudio Soto Lab) retweeted
Cambridge FTD@CambridgeFTD12 Oct 2021
Biomarker of synapse dysfunction [neuronal pentraxin 2 NPTX2] in CSF is the first to change in familial frontotemporal dementia #FTD ahead of #NFL and neuroinflammation markers 👍to Emma van der Ende and GENFI team DOI: 10.1093/brain/awab382 @Brain1878 @GENFI1 #SynapticHealth
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Mitchell Center for AD (Claudio Soto Lab) retweeted
Nature Biotechnology
@NatureBiotech3 Jun 2021
Spatial transcriptomics at subspot resolution with BayesSpace go.nature.com/3gd7nBw
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Mitchell Center for AD (Claudio Soto Lab) retweeted
Nature Biotechnology
@NatureBiotech8 Jun 2021
First author @edward130603 goes #behindthepaper on a tool for clustering analysis and resolution enhancement of spatial transcriptomics data bioengineeringcommunity.natu…
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Mitchell Center for AD (Claudio Soto Lab) retweeted
American Parkinson Disease Association@APDAParkinsons23 Jul 2021
🧵 One of the most asked questions about #ParkinsonsDisease is: what are the symptoms? Here are some fast facts to help keep you informed. Was there anything listed here you hadn’t heard of before? Let us know in the replies! (1/2) #tremor #insomnia #neurotwitter #neurology
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Interesting finding with pretty vast implications
Neuroscience News
@NeuroscienceNew22 Jul 2021
People who drink six or more cups of coffee a day have a 53% increased risk of developing dementia and a higher risk of stroke, a new study reports. #coffee #dementia #neuroscience #science neurosciencenews.com/coffee-…

High Coffee Consumption Linked to Smaller Brain Volume and Increased Dementia Risk - Neuroscience...

People who drink six or more cups of coffee a day have a 53% increased risk of developing dementia and a higher risk of stroke, a new study reports.

neurosciencenews.com
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Mitchell Center for AD (Claudio Soto Lab) retweeted
ShorterLab@ShorterLab23 Jul 2021
A multi-step nucleation process determines the kinetics of prion-like domain phase separation: nature.com/articles/s41467-0…

A multi-step nucleation process determines the kinetics of prion-like domain phase separation

Nature Communications - The nucleation mechanisms of biological protein phase separation are poorly understood. Here, the authors perform time-resolved SAXS experiments with the low-complexity...

nature.com
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Mitchell Center for AD (Claudio Soto Lab) retweeted
LashuelNeuroLab@LashuelLab2 May 2021
Simultaneous Detection of Six Isoforms of Tau Protein in Human Cerebrospinal Fluid by Multidimensional Mass Spectrometry-Based Targeted Proteomics pubs.acs.org/doi/10.1021/acs…

Simultaneous Detection of Six Isoforms of Tau Protein in Human Cerebrospinal Fluid by Multidimens...

Abstract. Abnormal expression of Tau protein can cause the development of Alzheimer’s disease (AD). So far, much evidence has demonstrated that Tau has mul

pubs.acs.org
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Mitchell Center for AD (Claudio Soto Lab) retweeted
Jonathan Kipnis 🟦
@jonykipnis28 Apr 2021
A new work from our lab (in collaboration with many exceptional labs at @WUSTLmed) by @Da_Mesquita_S (now PI @MayoClinic), attempting to link #MeningealLymphatics to human Alzheimer's (please read the supplemental figures - a lot of cool data there!) || nature.com/articles/s41586-0…
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Mitchell Center for AD (Claudio Soto Lab) retweeted
Jake Vogel@_JakeVogel_29 Apr 2021
Does Alzheimer’s disease pathology spread through the brain consistently across the population? We delve into this in our paper “Four distinct trajectories of tau deposition identified in Alzheimer’s disease”, now online at Nature Medicine. nature.com/articles/s41591-0… Thread below 1/

Four distinct trajectories of tau deposition identified in Alzheimer’s disease

Nature Medicine - Systematic characterization of longitudinal tau variability in human Alzheimer’s disease using an unbiased subtyping algorithm reveals four trajectories of tau deposition...

nature.com
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Mitchell Center for AD (Claudio Soto Lab) retweeted
Tony Wyss-Coray@wysscoray29 Apr 2021
and here is our simple web browser developed by Patricia Losada to look up the expression of your favorite gene in the human brain vasculature and in AD twc-stanford.shinyapps.io/hu…
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Mitchell Center for AD (Claudio Soto Lab) retweeted
Tony Wyss-Coray@wysscoray28 Apr 2021
Congrats @andcyang RyanVest @fabiankern13 to human brain vascular map & role in AD in collaboration with @SiegenthalerLab and Andreas Keller biorxiv.org/content/10.1101/…. Discovered 2 types of pericytes, one differentially lost in AD, PV fibroblast types & tie AD GWAS to vasculature
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Mitchell Center for AD (Claudio Soto Lab) retweeted
The Science of Parkinson's@ScienceofPD26 Apr 2021
"#Parkinsons disease is evolving from a clinical to a biomarker-supported diagnostic entity, for which earlier identification is possible, different subtypes with diverse prognosis are recognised, & novel disease-modifying treatments are in development" thelancet.com/journals/laneu…
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Mitchell Center for AD (Claudio Soto Lab) retweeted
Mike A. Nalls@mike_nalls26 Apr 2021
Congrats @SingletonNeuro, well deserved ... now you get to drop “acting” director from your email signature 🦾 #CARD nia.nih.gov/news/dr-andrew-s… – at Glen Echo, MD
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