MD-PhD student at @UTSWMedCenter & @WashUdbbs computational biology & tumor immunology | evidence-based medicine | lover of uncertainty
St. Louis, MO
Joined July 2020
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- Following312
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Reilly Alex Sample retweeted
What a week! So proud of MD-PhD Reilly Sample who defended his thesis today. Reilly has done deep genomic and mechanistic work to understand HOW anti-PD1 resistance develops in #headandneck #cancer. Could not be more proud of him - an amazing tour de force defense!! CONGRATS!
Our latest work is out in @CellRepMed, where we explore malignant cell MHC class II expression as a marker of productive anti-tumor immune response following checkpoint blockade. I enjoyed contributing to this story!
cell.com/cell-reports-medici…
Reilly Alex Sample retweeted
1. When you write something intended to be read by an important person, go through it and cut every unnecessary word.
2. The reader of anything you publish is an important person.
Reilly Alex Sample retweeted
Join @WashUGenetics next Thursday Sep.18 @ 12pm CST in Connor Auditorium for the 2nd Gary D. Stormo Computational & Systems Biology Lecture when Timothy Hughes, PhD, presents “Codebook: sequence specificity of human transcription factors”, hosted by Dr. Mike White @genologos
Reilly Alex Sample retweeted
An infographic presented by the AHNS Basic and Translational Science Service
The promise and uncertainties of applying the new neoadjuvant anti-PD1 standard created by KEYNOTE-689
#AHNS #neoadjuvant #immunotherapy #HNSCC
Had a fantastic time learning from the brightest minds in systems immunology at #cshlsysimm last month with @cshlmeetings. Grateful to @WashUGenetics for supporting my travel!
Reilly Alex Sample retweeted
Thank you, Mike, for sharing this announcement about Susan’s election to the National Academy of Sciences. She is an outstanding scientist, a valued colleague, and an asset to our exceptional Genetics department here at WashU. I am lucky to have her as my office and lab neighbor, she makes the department an even better place. Congratulations Susan! @WashUGenetics #genetics
I am a couple of days late, but a huge congrats to our own @WashUGenetics Susan Dutcher on her election to the National Academy of Sciences!
nasonline.org/news/2025-nas-…
Reilly Alex Sample retweeted
Highly speculative post: Autoimmune diseases have benefitted from a repurposing of modalities from blood malignancies. Imo, once we find the immune cell subpopulations driving age-related diseases, we'll see repurposing from autoimmune -> aging
writingruxandrabio.com/p/aut…
Reilly Alex Sample retweeted
Nature research paper: DNA-guided transcription factor interactions extend human gene regulatory code
go.nature.com/3Rahjyp
Reilly Alex Sample retweeted
And, perhaps the hardest of it all, the Courage to stare Nature in its face, unyielding and impersonal as it is, armed only with rudimentary tools.
It is this unyielding, cruel quality of Nature that taught me the most important lesson of all: Humility.
writingruxandrabio.com/p/tho…
Reilly Alex Sample retweeted
This year marks 50 years of excellence at the WashU Medicine Department of Genetics @WashUGenetics ! Join our 50th Anniversary Symposium on April 24th and watch below what our faculty say about the great community here!
Check out our speakers and register:
genetics.wustl.edu/departmen…
My ~6-year-old cousin to everyone at our Thanksgiving: "Reilly is gonna be a doctor one day but right now his patients are mice!"
Incredible.
It was a tremendous honor to receive the inaugural Gary D. Stormo Fellowship, & to share the stage with these leaders in genetics & computational biology. Thank you to @gdstormo, @ScientistAtLarj for his excellent talk, @gzhao11 for organizing this event, @twang5 & @WashUGenetics
Reilly Alex Sample retweeted
Phenomenal day with Dr Mark Varvares from @MassEyeAndEar, our 2024 Gershon Spector visiting lecturer! Incredible insights about #leadership and #headandneck #cancer, followed by his keynote at our first ever h&n #survivorship symposium. @WUSTL_ENT @WashUHNTC. He inspired us all!
Who'd've guessed that me screwing up my sectioning would become the start of my alternative career in the visual arts
This was a fun deep dive on hybrid epithelial-mesenchymal cell states in #cancer. We've learned a lot, but there's still so much more to discover... More exciting #EMT-related findings to come!
A comprehensive review on the epigenetic regulation of hybrid epithelial-mesenchymal cell states in #cancer from @SidPuram & @ReillyAlexS! Learn about the various epigenetic factors that drive E/M plasticity and future strategies to target them.
🧪nature.com/articles/s41388-0…
Seems like just yesterday I was a 3rd-year med student in the hospital. Now sitting here learning Viterbi decoding. Life really takes you in unexpected directions...
Reilly Alex Sample retweeted
#CRBStories
She became an HHMI investigator in her mid-30s and was the first out gay investigator. She personally lobbied Thomas Cech, the President of HHMI at the time, to extend healthcare benefits to same-sex partners of investigators.
#NobelPrize
Secured myself some funding through the Genome Analysis Training Program T32 at @WUSTLdbbs and @genome_gov! Me and my work both feel seen 🥹
