We aim to shed new light on the complex networks formed in #melanoma, and learn how we can utilize this information to treat melanoma patients @WeizmannScience
Israel
Joined June 2023
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Proud of @samuels_yardena for her fascinating plenary session at the @AACR annual meeting in Chicago! A great thank you to the program committee chairs, Drs. Matthew G. Vander Heiden and Lillian L. Siu for this amazing opportunity.
@mvh_lab @lillian_siu #AACR25 #AACR2025
Samuels - Lab retweeted
Translation dysregulation may serve as a new source for identifying cancer-associated antigens, and may also help to predict responses to checkpoint blockade bit.ly/3E4OMY8 @chen_weller @samuels_yardena @Samuels_lab #CheckpointBlockade #CancerImmunotherapy
Samuels - Lab retweeted
Thrilled to share our work in Cancer Cell! Huge thanks to my PI and mentor @samuels_yardena ,OsnatBartok, and our collaborators @chrismcginnis,@Satpathology , Andreas Schlosser,@EytanRuppin & more. We reveal how impaired translation fidelity enhances anti-tumor immunity!🧵(1/8)
Samuels - Lab retweeted
In a study published in @Cancer_Cell, researchers from @Samuels_lab manipulated cancer cells into making themselves visible to the immune system, creating a new approach that gives hope to patients with previously untreatable disease>>bit.ly/cancer-expose-eng @samuels_yardena
Samuels - Lab retweeted
AACR - The Various Layers of Intratumor Heterogeneity and Their Impact on Tumor Immunity
@AACR @samuels_yardena
oncodaily.com/blog/intratumo…
#Cancer #CancerResearch #AACR #MedX #MedNews #MedEd #IntratumorHeterogeneity #Medicine #Health #Oncology #OncoDaily
Samuels - Lab retweeted
The Various Layers of Intratumor Heterogeneity and Their Impact on Tumor Immunity:
Yardena Samuels will address this topic in a plenary session on Targeting the Cancer Ecosystem (Tuesday, April 29) at #AACR25. Learn more:
brnw.ch/21wRxxa
@samuels_yardena
Our new paper on Macrophage Migration Inhibitory Factor (MIF) as a key regulator of immune evasion in melanoma, is now published in @CD_AACR (full study here:aacrjournals.org/cancerdisco…)
Step-by-step breakdown of this exciting research follows:
7/8 Our findings suggest that MIF expression is an important determinant of aggressive tumor growth in low-ITH tumors in melanoma and could lead to new strategies for treating patients with homogeneous, high-MIF-expressing tumors that don't respond to immune checkpoint therapy.
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8/8 All this would not be possible without the hard work of Sapir Cohen Shvefel, @joyp_ai @sathpathology @NCIEytanRuppin, @samuels_yardena and colleagues.
@weizmannScience
#CancerResearch #Immunotherapy
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Samuels - Lab retweeted
New study in @Samuels_lab, published in Cancer Discovery, reveals a key player in the development of aggressive melanoma tumors: a small immune system protein called Mif. Findings promise to open new directions of therapy >> bit.ly/3F8O8sK
@samuels_yardena
Congratulations to our very own Sapir Cohen Shvefel! Her paper on Macrophage Migration Inhibitory Factor (MIF) as a key regulator of immune evasion in #melanoma, is now published in @CD_AACR ! Full article here: aacrjournals.org/cancerdisco…
Samuels - Lab retweeted
Thrilled to share that our new paper on Macrophage Migration Inhibitory Factor (MIF) as a key regulator of immune evasion in melanoma, is now published in @Cancer Discovery! Find the full study here: aacrjournals.org/cancerdisco…