Chen Weller (@chen_weller) profile picture

Chen Weller

@chen_weller
Joined April 2020
  • Tweets181
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  • Followers62
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Photo by Chen Weller (@chen_weller)Photo by Chen Weller (@chen_weller)Photo by Chen Weller (@chen_weller)Photo by Chen Weller (@chen_weller)Photo by Chen Weller (@chen_weller)Photo by Chen Weller (@chen_weller)Photo by Chen Weller (@chen_weller)Photo by Chen Weller (@chen_weller)Photo by Chen Weller (@chen_weller)Photo by Chen Weller (@chen_weller)
Thrilled to share our work in Cancer Cell! Huge thanks to my PI and mentor @samuels_yardena ,OsnatBartok, and our collaborators @chrismcginnis,@Satpathology , Andreas Schlosser,@EytanRuppin & more. We reveal how impaired translation fidelity enhances anti-tumor immunity!๐Ÿงต(1/8)
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Moshe Biton (@bitonm) profile picture
Moshe Biton@bitonmMay 13
Excited to share our new paper in Nature Immunology! ๐Ÿฆ ๐Ÿ”ฌ nature.com/articles/s41590-0โ€ฆ We uncover a central role for intestinal stem cells in defending the tissue against Salmonella infection. A huge thanks to all collaborators and team members who made this work possible!
An inflammasome-driven differentiation program in intestinal stem cells protects against Salmonella...

An inflammasome-driven differentiation program in intestinal stem cells protects against Salmonella...

Nature Immunology - Salmonella-invaded intestinal stem cells activate an inflammasome-driven differentiation program toward antimicrobial Paneth cells, revealing a protective stem cell defense...

nature.com
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IdoAmitLab (@IdoAmitLab) profile picture
IdoAmitLab@IdoAmitLabMar 9
Thank you @CancerCell for featuring our cover! ๐Ÿ Inspired by honeybee โ€œsocial immunityโ€ where colonies detect and manage sick nestmates, we engineered TME-regulated armored TREM2 CAR T cells to unmask and dismantle immunosuppressive niches in solid tumors @GalYagel @D_Rimini
Cancer Cell (@Cancer_Cell) profile pictureCancer Cell@Cancer_CellMar 9
Dive into our March issue, out now: cell.com/cancer-cell/issue?pโ€ฆ
Image from Cancer Cell (@Cancer_Cell)
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400,000 supporters stand with the hostage families, demanding a comprehensive deal to bring ALL the hostages home. Credit: Aviv Atlas
Image from Bring Them Home Now (@bringhomenow)
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โ€œThere are still 50 hostages in Gaza. President Trump, we trust you to do all in your power to secure their release and bring peace to the regionโ€ Ronen Neutra, father of hostage Omer Neutra, stood by the water, in front of the Statue of Liberty, where American and Israeli Navy Seals jumped into the water, thinking of the brave men and women who lost their lives in the name of freedom: โ€œIn honor of those who fought and were killed defending our values of freedom and liberty, the same values Omer fought for when he was taken by Hamas 680 days agoโ€ @POTUS @realDonaldTrump @VP @SecRubio @SEPeaceMissions @SteveWitkoff @aboehler @PressSec @WhiteHouse @RapidResponse47 @NavySEALfnd @BringOmerHome
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Chen Weller retweeted
Eyal Eshel (@ESHEL2003) profile picture
Eyal Eshel
@ESHEL200310 Aug 2025
ืงื—ื• ืืช ื”ืชืžื•ื ื”, ืฉืชืคื• ืื•ืชื” ืืฆืœื›ื ื•ื‘ื›ืœ ืžืงื•ื ืืคืฉืจื™, ื™ื—ื“ ืื ื—ื ื• ืžืกื•ื’ืœื™ื ืœื™ื™ืฆืจ ืฉื‘ื™ืชื” ืฉืœ ื”ืžืฉืง ืžืœืžื˜ื” ืœืžืขืœื”! ืื—ืจื™ ืฉืฉื™ืชืคืชื, ื›ื ืกื• ืœืœื™ื ืง, ืชืจืฉืžื• ื›ืžื™ ืฉืžืชื›ื•ื•ืŸ ืœื ืœื”ื’ื™ืข ืœืขื‘ื•ื“ื” ื‘ื™ื•ื ืจืืฉื•ืŸ. ื”ื˜ื•ืคืก ืžื™ื•ืขื“ ื”ืŸ ืœื—ื‘ืจื•ืช ื•ื”ืŸ ืœืื–ืจื—ื™ื•ืช ื•ืื–ืจื—ื™ื saveourhostages.co.il/
Image from Eyal Eshel (@ESHEL2003)
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ื ืชื ื™ื”ื• ืžื•ื‘ื™ืœ ืืช ื™ืฉืจืืœ ื•ืืช ื”ื—ื˜ื•ืคื™ื ืœืื‘ื“ื•ืŸ ื‘ื”ืžืฉืš ืœืคืจืกื•ืžื™ื ืขืœ ื”ืชื•ื›ื ื™ื•ืช ื ื•ืกืคืช ืœื”ืจื—ื‘ืช ื”ืžืœื—ืžื”: ื ืชื ื™ื”ื• ืžื›ื™ืŸ ืืช ืชื•ื›ื ื™ืช ื”ื”ื•ื ืื” ื”ื’ื“ื•ืœื” ื‘ื™ื•ืชืจ. ื”ื“ื™ื‘ื•ืจื™ื, ืฉื›ื‘ืจ ื ืฉืžืขื• ืฉื•ื‘ ื•ืฉื•ื‘, ืขืœ ืฉื—ืจื•ืจ ื—ื˜ื•ืคื™ื ืชื•ืš ื›ื“ื™ ื”ื›ืจืขื”, ื”ื ืจืžื™ื™ื” ื•ื”ื•ื ืืช ื”ืฆื™ื‘ื•ืจ. ื›ื‘ืจ 22 ื—ื•ื“ืฉื™ื ืฉืžื•ื›ืจื™ื ืœืฆื™ื‘ื•ืจ ืืช ื”ืืฉืœื™ื” ืฉืœื—ืฅ ืฆื‘ืื™ ื•ืœื—ื™ืžื” ืขืฆื™ืžื” ืชื—ื–ื™ืจ ืืช ื”ื—ื˜ื•ืคื™ื. ืขื•ื“ ื‘ื˜ืจื ื ื›ืชื‘ื” ื”ื˜ื™ื•ื˜ื” ืœื”ืกื›ื ื›ื•ืœืœ ื•ื›ื‘ืจ ืื•ืžืจื™ื ืœื ื• ืฉืื™ืŸ ื”ื™ืชื›ื ื•ืช ืœื”ืกื›ื. ื”ืืžืช ืฆืจื™ื›ื” ืœื”ื™ืืžืจ: ื”ืจื—ื‘ืช ื”ืžืœื—ืžื” ืžืกื›ื ืช ืืช ื—ื™ื™ ื”ื—ื˜ื•ืคื™ื ืฉื ืžืฆืื™ื ื›ื‘ืจ ื›ืขืช ื‘ืกื›ื ืช ืžื•ื•ืช ืžื™ื™ื“ื™. ืจืื™ื ื• ืืช ืชืžื•ื ื•ืชื™ื”ื ื”ืžืฆืžืจืจื•ืช ืฉืœ ื”ื—ื˜ื•ืคื™ื ื‘ืžื ื”ืจื•ืช, ื”ื ืœื ื™ืฉืจื“ื• ืขื•ื“ ื™ืžื™ื ืืจื•ื›ื™ื ืฉืœ ืชื•ืคืช. ื”ืจื—ื‘ืช ื”ืœื—ื™ืžื”, ื‘ืคืขื ื”ืžื™ ื™ื•ื“ืข ื›ืžื”, ื”ื™ื ื”ื‘ื˜ื—ืช ื”ื›ื™ืฉืœื•ืŸ ืฉืœ ื”ืžืื”. ืื™ืŸ ื‘ื• ืœื ื ื™ืฆื—ื•ืŸ ื•ืœื ืชืงื•ืžื”. ื—ื™ืกืœื ื• ืืช ื›ืœ ืจืืฉื™ ื”ื—ืžืืก, ื ื™ืฆื—ื ื• ื‘ืœื‘ื ื•ืŸ ื•ื‘ืื™ืจืืŸ. ืื™ืŸ ื ื™ืฆื—ื•ืŸ ื’ื“ื•ืœ ืžื–ื”. ืจื•ื‘ ื”ืฆื™ื‘ื•ืจ ื‘ื™ืฉืจืืœ ืชื•ืžืš ื‘ื”ื—ื–ืจืช ื”ื—ื˜ื•ืคื™ื ื•ื”ืคืกืงืช ื”ืœื—ื™ืžื”. ื”ืจืžื˜ื›ืดืœ ืžืชื ื’ื“ ืœื”ืžืฉืš ืžืœื—ืžื” ืขืงืจื” ื‘ืจืฆื•ืขื”. ื™ืฉ ืจืง ื“ืจืš ืื—ืช ืœื ื™ืฆื—ื•ืŸ - ื”ืฉื‘ืช 50 ื”ื—ื˜ื•ืคื™ื ื•ื”ื—ื˜ื•ืคื” ื”ื‘ื™ืชื”, ืกื™ื•ื ื”ืžืœื—ืžื” ื•ืื– ืฉื™ืงื•ื ื•ืชืงื•ืžื” ืœื™ืฉืจืืœ. ื ื—ื–ื™ืจ. ื ืงื•ื.
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โ€œThey are on the absolute brink of death. In their current, unimaginable condition, they may have only days left to live.โ€ Ilay, brother of hostage Evyatar David, spoke tonight at the rally at Hostages Square, a day after Hamas released Evyatar's devastating video from captivity. A deal is more urgent than ever. Their lives are not forfeit. Bring them home, NOW. #BringThemHomeNow #UntilTheLastHostage
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The spectacular Carmit Levy is telling us about the fascinating interactions of melanosomes with T cells in melanoma #ISCR2025
Image from ISCR- The Israeli Society for Cancer Research (@IscrFor)
Image from ISCR- The Israeli Society for Cancer Research (@IscrFor)
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ื–ื”ื• ืกื™ืคื•ืจื• ืฉืœ ืจืก"ื‘ ื‘ืžื™ืœ' ืจืŸ ื™ืขื‘ืฅ ื–"ืœ. ืจืŸ ื‘ื ื ื”ื‘ื›ื•ืจ ืฉืœ ื™ื”ื•ื“ื™ืช ื•ืื‘ื™, ื•ืื—ื™ื”ื ื”ื’ื“ื•ืœ ืฉืœ ื‘ืŸ, ื’ืœ, ื ื•ื™ ื•ื ื™ืจ. ื”ื™ื” ื ืฉื•ื™ ืœืชืžืจ ื•ืื‘ ืœืืจื‘ืขื” ื™ืœื“ื™ื - ืื™ืชื™, ื ื’ื”, ืื•ืจ ื•ืจื ื”, ืฉื ื•ืœื“ื” ื—ื•ื“ืฉ ืœืื—ืจ ื ืคื™ืœืชื•. ืจืŸ ื”ื™ื” ื ืขืจ ื—ื›ื, ืกืงืจืŸ ื•ืขืงืฉืŸ, ืื”ื•ื‘ ืขืœ ื—ื‘ืจื™ื•. ืื”ื‘ ืืช ืžื›ื‘ื™ ืชืœ ืื‘ื™ื‘ ื‘ื›ืœ ืขื ืฃ, ื‘ืขื™ืงืจ ื‘ื›ื“ื•ืจื’ืœ ื•ืืช ื”ืื”ื‘ื” ื”ื–ื• ื”ื•ืจื™ืฉ ืœืื—ื™ื• ื”ืงื˜ื ื™ื ื•ืœื™ืœื“ื™ื•. ืžื’ื™ืœ 14 ืœื ืคืกืคืก ืืฃ ืžืฉื—ืง, ื•ืชืžื™ื“ ื—ื–ืจ ื”ื‘ื™ืชื” ืฆืจื•ื“ ืžื”ืขื™ื“ื•ื“. ื‘ื’ื™ืœ 18 ื”ืชื’ื™ื™ืก ืœืฆื”"ืœ ื•ืฉื™ืจืช ื‘ืฆื ื—ื ื™ื. ื™ืฆื ืœืงื•ืจืก ืžื›ื™"ื, ื”ื“ืจื™ืš ื‘ื‘ื™ืกืœ"ื— - ื•ืฉื ื’ื ื‘ื™ืฆืข ืืช ื›ืœ ืฉื™ืจื•ืช ื”ืžื™ืœื•ืื™ื ืฉืœื•, ื‘ืžืฉืš 18 ืฉื ื”. ืฉื ื” ืื—ืจ ืฉื ื”, ืœืœื ื”ื™ืกื•ืก, ืžืชื•ืš ืชื—ื•ืฉืช ืฉืœื™ื—ื•ืช ืืžื™ืชื™ืช. ืจืŸ ื”ื™ื” ืื‘ื ืžื“ื”ื™ื - ืžืขื•ืจื‘, ื ื•ื›ื—, ืชื•ืžืš, ืชืžื™ื“ ืฉื, ื‘ื’ื•ืฃ ื•ื‘ื ืคืฉ, ืœืžืขืŸ ื™ืœื“ื™ื•. ืื“ื ืขืจื›ื™, ืฉืชืžื™ื“ ืขื–ืจ, ื”ืชื ื“ื‘, ื•ืœื ืืžืจ "ืœื" - ื‘ื›ืœ ืฉืขื” ื•ื‘ื›ืœ ืžืงื•ื. ื—ื‘ืจื™ื• ืžืขื™ื“ื™ื ืฉื”ื™ื” "ื”ื—ื‘ืจ ื”ื›ื™ ื˜ื•ื‘" ืฉืœ ื›ื•ืœื. ื”ืขืจื›ื™ื ืฉื”ื•ื‘ื™ืœื• ืืช ืจืŸ ื”ื™ื•: ื›ื™ื‘ื•ื“ ืื‘ ื•ืื, ืื”ื‘ืช ื”ืžืฉืคื—ื”, ืื”ื‘ืช ื”ืื“ื ื•ืื”ื‘ืช ื”ืืจืฅ. ื‘-7.10.2023, ืขื ืคืจื•ืฅ ื”ืžืœื—ืžื” ืจืŸ ื’ื•ื™ืก ืœืžื™ืœื•ืื™ื ื•ืฉื™ืจืช ื›ื—ืฆื™ ืฉื ื”. ืฉืœื•ืฉื” ื™ืžื™ื ืœืื—ืจ ืชื—ื™ืœืช ื”ืœื—ื™ืžื”, ื›ืฉ"ืื—ื™ื ืœืกืžืœ" (ืขืžื•ืชืช ืื•ื”ื“ื™ ืžื›ื‘ื™ ืช"ื) ืคืชื—ื” ื—ืž"ืœ ืกื™ื•ืข ืœืœื•ื—ืžื™ื, ืฉืืœื• ืืช ืจืŸ ืื ื—ืกืจ ืœื• ืฆื™ื•ื“ ื•ืžื” ื ื™ืชืŸ ืœื”ื‘ื™ื ืœืžื—ืœืงื” ืฉืœื•. ื”ื‘ืงืฉื” ื”ื™ื—ื™ื“ื” ืฉืœื• ื”ื™ื™ืชื”: ื“ื’ืœื™ ื™ืฉืจืืœ. ื”ื•ื ื”ืกื‘ื™ืจ ืฉืื™ืŸ ื“ื’ืœื™ื ืขืœ ื ื’ืž"ืฉื™ื ื•ืฉื—ืฉื•ื‘ ืœื• ืฉื”ื“ื’ืœ ื™ืชื ื•ืกืก ื‘ื’ืื•ื•ื”. ื•ื›ืš ื”ื™ื” - ื”ื•ื ืงื™ื‘ืœ ืืช ื”ื“ื’ืœื™ื, ื•ื“ืื’ ืœืชืœื•ืช ืื•ืชื ื’ื‘ื•ื” ื›ื›ืœ ื”ืืคืฉืจ. ืจืŸ ื ืคืœ ื‘ืขืช ืคืขื™ืœื•ืช ืžื‘ืฆืขื™ืช ื‘-16.5.2024, ื”ื™ื•ื ืœืคื ื™ ืฉื ื”. ื”ื•ื ื‘ื—ืจ ืœืกื›ืŸ ืืช ื—ื™ื™ื• ืžืชื•ืš ืชื—ื•ืฉืช ืฉืœื™ื—ื•ืช ืขืžื•ืงื”, ื›ื“ื™ ืฉืชื•ืฉื‘ื™ ืžื“ื™ื ืช ื™ืฉืจืืœ, ื•ื‘ืคืจื˜ ืชื•ืฉื‘ื™ ื”ืขื•ื˜ืฃ, ื™ื•ื›ืœื• ืœื—ื™ื•ืช ื—ื™ื™ื ื‘ื˜ื•ื—ื™ื ื•ืฉืงื˜ื™ื. ื”ืฆื•ื•ืื” ืฉืจืŸ ื”ืฉืื™ืจ ืœื ื•: ืœื”ื™ื•ืช ืชืžื™ื“ ืื•ืคื˜ื™ืžื™ื™ื ื•ืฉืžื—ื™ื, ืœืจืื•ืช ืืช ื”ื˜ื•ื‘ ื‘ื›ืœ ื“ื‘ืจ, ืœืขื–ื•ืจ ืœืื—ืจื™ื ื•ืœืชืช ืืช ื”ื›ื•ืœ ืœืžืขืŸ ืžื“ื™ื ืช ื™ืฉืจืืœ. ื‘ืŸ 39 ื‘ืžื•ืชื•. ื’ื™ื‘ื•ืจ ื™ืฉืจืืœ. ืฉื ื” ื—ืœืคื” ืืš ื”ืื•ื‘ื“ืŸ ืจืง ื”ื•ืœืš ื•ื’ื“ืœ ื•ื›ืš ื”ื’ืขื’ื•ืข ืฉืœ ืžืฉืคื—ืชื• ื•ื—ื‘ืจื™ื•. ื™ื”ื™ ื–ื›ืจื• ื‘ืจื•ืš๐Ÿ‡ฎ๐Ÿ‡ฑ๐Ÿ•ฏ ืฉื ื”ื™ื” ืจืื•ื™ื™ื.
Image from ื™ื•ืกืฃ ื—ื“ืื“ - Yoseph Haddad (@YosephHaddad)
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ืื™ืŸ ืœื™ ืืจืฅ ืื—ืจืช, ื’ื ืื™ืŸ ืœื™ ื“ืจื›ื•ืŸ ื–ืจ. ื™ืฉ ืœื™ ืจืง ืืช ืžื“ื™ื ืช ื™ืฉืจืืœ, ืื ื™ ืžืงื•ื•ื” ืฉื”ื™ื ืœื ืชืฉืื™ืจ ืื•ืชื™ ืžืื—ื•ืจ. ื ืžืจื•ื“.
Image from ื•ื™ืงื™ ื›ื”ืŸ, ืืžื ืฉืœ ื ืžืจื•ื“ (@bringnimrod)
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Proud of @samuels_yardena for her fascinating plenary session at the @AACR annual meeting in Chicago! A great thank you to the program committee chairs, Drs. Matthew G. Vander Heiden and Lillian L. Siu for this amazing opportunity. @mvh_lab @lillian_siu #AACR25 #AACR2025
Image from Samuels - Lab (@Samuels_lab)
Image from Samuels - Lab (@Samuels_lab)
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Thanks a lot @ACIR_org for highlighting our work and generating this great illustration!!
ACIR (@ACIR_org) profile pictureACIR
@ACIR_org2 Apr 2025
Translation dysregulation may serve as a new source for identifying cancer-associated antigens, and may also help to predict responses to checkpoint blockade bit.ly/3E4OMY8 ย @chen_weller ย @samuels_yardena @Samuels_lab #CheckpointBlockade #CancerImmunotherapy
Image from ACIR (@ACIR_org)
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Online Now: Translation dysregulation in cancer as a source for targetable antigens dlvr.it/TJnkpw
Image from Cancer Cell (@Cancer_Cell)
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This has been an incredible journey led by @chenweller, Osnat Bartok, with amazing collaborators @Chrismcginnis, @AnsumanSatpathy, Andreas Schlosser, @EytanRuppin & more. Thanks to @CancerCell for an exceptional review process.
Chen Weller (@chen_weller) profile pictureChen Weller@chen_weller27 Mar 2025
Thrilled to share our work in Cancer Cell! Huge thanks to my PI and mentor @samuels_yardena ,OsnatBartok, and our collaborators @chrismcginnis,@Satpathology , Andreas Schlosser,@EytanRuppin & more. We reveal how impaired translation fidelity enhances anti-tumor immunity!๐Ÿงต(1/8)
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In a study published in @Cancer_Cell, researchers from @Samuels_lab manipulated cancer cells into making themselves visible to the immune system, creating a new approach that gives hope to patients with previously untreatable disease>>bit.ly/cancer-expose-eng @samuels_yardena
Image from Weizmann Institute (@WeizmannScience)
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Patient data completed the picture: Primary melanoma tumors with low TYW2 showed enhanced responses to ICB, even in patients with low TMB (@TiangenC ). Translation fidelity defects may help predict immunotherapy responders, opening new paths for precision cancer treatment. (7/8)
Image from Chen Weller (@chen_weller)
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โœจ We are thankful to the @CancerCell editorial team ,the reviewers for their constructive comments and all co-authors involved! (8/8)
Image from Chen Weller (@chen_weller)
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