Countering deleterious phase transitions in ALS/FTD, PD, AD, and related disorders @Penn @PennMedicine @bb_upenn @BMBGGUPENN @PGGUPenn @PennNGG @CAMBUpenn

University of Pennsylvania
Joined January 2012
ShorterLab retweeted
Sixers season opener is tonight. Every fan will get a white Sixers shirt #throwtheballup
40
163
37
3,331
106,480
I'm obsessed with these empty clathrin cages people are seeing in neurons, and don't understand why others are not. So I put everything together and wrote a brief review (Current Opinion in Neurobiology, free access for 50 days): sciencedirect.com/science/ar…
2
5
46
2,670
SIXERS BEAT KNICKS 106-100 IN SEASON OPENER AT MSG TYRESE MAXEY WITH 28 POINTS JAYLEN BROWN WITH 19, LEBRON JAMES WITH 14, AND JOEL EMBIID WITH 13 #THROWTHEBALLUP PLAY THE SONG
25
359
10
3,174
62,970
ShorterLab retweeted
W.
65
759
36
6,738
89,292
ShorterLab retweeted
FIRST W OF THE SEASON. @Bloom_Energy
368
3,948
510
23,292
306,525
ShorterLab retweeted
BUSINESS HANDLED.
259
2,317
274
12,357
365,941
ShorterLab retweeted
116
2,201
266
11,075
495,283
ShorterLab retweeted
the time has come. @Bloom_Energy
86
1,488
221
7,003
255,762
ShorterLab retweeted
meet the sixers. 🤝
84
801
73
5,942
115,099
ShorterLab retweeted
City fit for a King👑
End of an era. The Phillies Daycare mural (last photo) on the side of Garage in Fishtown has come down and a new mural is being put up as we speak I talked to the artist Liam who showed me what the new mural is going to be, and I think people will be excited about it. Should be done by the end of the week, progress pics to come🏀🌃
5
18
1
370
9,570
Monomeric TDP-43 binds GU-rich RNA via its NTD but only its oligomers block cryptic exon inclusion biorxiv.org/content/10.64898…
2
6
770
Engineered Chimeric Proteins Functionally Replace ALS-causing Endogenous FUS and TDP-43 to Improve Neuronal Health biorxiv.org/content/10.64898…
3
2
332
The ALS community has lost one of its most powerful voices. Brooke Eby was diagnosed with ALS in 2022 at just 33 years old. Instead of retreating, she made a choice that changed how the world sees this disease: she shared it all, with honesty and a sense of humor that made it impossible to look away. She brought her employer Salesforce into the fight and raised more than $1 million for research. She helped build ALStogether so people with ALS could find one another. And she shared her story with the Today Show, The New York Times and People. In 2024, the ALS Association was proud to name her an ALS Hero. "Brooke made ALS impossible to ignore, and she made it impossible not to love her while she did it," said ALS Association President and CEO Calaneet Balas. Brooke died Thursday at 37. We will keep going until ALS is livable for everyone, and then cured. Read our full statement: als.org/stories-news/brooke-…
61
216
60
1,690
76,677
ShorterLab retweeted
The end of Summer on the Schuykill River
4
96
1,622
LOOK AT THIS BEAUTIFUL ABS PAINTING 🎨
94
799
103
8,565
972,441
PHILLIES WIN GAME 2 IN EXTRAS WE’RE TALKING ABOUT THE FIGHTINS
12
234
6
1,634
59,197
THE FIGHTIN PHILS BABY
216
971
180
5,152
120,896
ShorterLab retweeted
Today we announced pharmacokinetic (PK), regulatory, and manufacturing advances that enable a higher-dose, twice-daily oral regimen of neflamapimod in future clinical trials. You can read more here: ir.cervomed.com/news-release…
1
4
424
RED OCTOBER IS BACK WE’RE TALKING ABOUT THE FIGHTINS
19
217
14
1,733
76,849