@SosaLab4

Structure & function of biological molecular machines

 Bronx, NY
einstein.yu.edu/faculty/236/hernando-sosa/
Joined May 2020
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Congrats @arnegennerich and all, this is a huge breakthrough to have such detailed structures of KIF1A bound to microtubules! Very important work. Thank you from all our families and the whole community.
Arne
@arnegennerich3 Feb 2023
The Sosa and Gennerich Labs report the fist near-atomic structures of KIF1A bound to microtubules. biorxiv.org/content/10.1101/…

High-Resolution structures of microtubule-bound KIF1A and its pathogenic variant P305L

Mutations in the Kinesin-3 motor KIF1A, a microtubule (MT)-associated motor protein, cause devastating neurodevelopmental and neurodegenerative diseases termed KIF1A-associated neurological disorders...

biorxiv.org
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18 new #cryoEM structures of the kinesin molecular motor KIF14 reveal its translocation mechanism @SosaLab4 biorxiv.org/cgi/content/shor… Collaboration with Kwok lab. Data collected at @SEMC_NYSBC #EinsteinMed #MTmotors #kinesins #microtubules #biophysics @cryoEM_Papers #cellbiology
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Sosa lab @EinsteinMed provides structural insights into kinesin-13 mediated microtubule depolymerisation. go.nature.com/2HQuXoi
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