EST. Randolph, MA. PhD in Cell and Molecular Biology
Joined January 2020
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Jaice Rottenberg retweeted
Got out of the nucleus! Tested ~30,000 tiles from human RNA-binding proteins, found lots of domains that downregulate RNA&built an inducible synthetic RNA-binding protein for keeping target RNA at constant intermediate levels: biorxiv.org/content/10.1101/… So many follow-up projects!
Do human RNA-binding proteins have modular regulatory domains that downregulate RNA lifetimes? Our preprint @BintuLab studying this question is now out on bioRxiv, where we indeed identify small domains in RBPs that potently induce RNA degradation! biorxiv.org/content/10.1101/… (1/9)
Jaice Rottenberg retweeted
Take a look at this recently published study in LSA: A large-scale cancer-specific protein–DNA interaction network @fuxmanlab @annaabananabell @yunwei_lu @BU_Tweets
hubs.ly/Q02GY1KD0
Jaice Rottenberg retweeted
FREE to read at authors.elsevier.com/a/1jAo2… till July 19th!
Excited to share our review examining viral cis-regulatory elements as sensors of cellular states out now in @TrendsGenetics! sciencedirect.com/science/ar…
Jaice Rottenberg retweeted
Exited to share our recent review on viral elements and their role in sensing cellular and environmental cues!!! Great work by @TheRealJRott @TommyTaslim5 @LFSoto12 @camilam59287155 and @Lumartcues
Jaice Rottenberg retweeted
Viral cis-regulatory elements as sensors of cellular states and environmental cues dlvr.it/T7d7nS
Excited to share our review examining viral cis-regulatory elements as sensors of cellular states out now in @TrendsGenetics! sciencedirect.com/science/ar…
This effort was co-piloted by my fellow @fuxmanlab member @TommyTaslim5 with key contributions from @LFSoto12, @Lumartcues, and @camilam59287155.
Jaice Rottenberg retweeted
Excited to share our latest preprint on TF isoforms! Excellent tweetorial by @kaia_mattioli This is a large collaboration with the a Vidal, Bulyk, Sahni, and Salomonis labs and many other authors. The project was led by @LukeLambs , Kaia, and @cssantoso_
excited to share the first story from my postdoc today!! we profiled hundreds of transcription factor (TF) isoforms & found that two-thirds of alternative TF isos differ from their cognate reference iso in at least 1 key molecular activity
biorxiv.org/content/10.1101/…
Jaice Rottenberg retweeted
The first “Berenson et al.” is out in Nature Communications! Super proud of this work and thankful to all involved. 👩🏼🔬🧬
We are very excited to see our paper published in @NatureComms led by the amazing Anna Berenson (@annaabananabell)! We introduce paired yeast one-hybrid (pY1H) assays to study cooperativity and antagonism between transcription factors (TFs). nature.com/articles/s41467-0… 1/6
Jaice Rottenberg retweeted
We are very excited to see our paper published in @NatureComms led by the amazing Anna Berenson (@annaabananabell)! We introduce paired yeast one-hybrid (pY1H) assays to study cooperativity and antagonism between transcription factors (TFs). nature.com/articles/s41467-0… 1/6
So incredibly proud of my undergraduate mentee @JordynChoe who has the opportunity to present at this year’s @BU_UROP symposium!
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Jaice Rottenberg retweeted
Now online! SARS-CoV-2 variants evolve convergent strategies to remodel the host response dlvr.it/SwRMmz
Jaice Rottenberg retweeted
3. long-awaited dino - we love to see a dino from twitter make it to our lab!
ALT A multicolored dino with terrifying teeth, webbed feet, and an impressive sail.
It ain’t much, but I used all the color options on my multicolor pen - and that must count for something. I hope you like it @plasmidsaurus!
Jaice Rottenberg retweeted
Epstein-Barr virus evades restrictive host chromatin closure by subverting B cell activation and germinal center regulatory loci dlvr.it/SthbvG
Jaice Rottenberg retweeted
Our latest paper is out today (with @axmukund @JoshTycko and many other talented trainees): High-throughput functional characterization of combinations of transcriptional activators and repressors, at Cell Systems cell.com/cell-systems/fullte…
This is bananas 🍌
Nature research paper: RNA polymerase II associates with active genes during DNA replication go.nature.com/44RRh84
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