
To inform on Insulin Resistance, Diabetes, Obesity, CVD, and other metabolic conditions. Earn CME/MOC at #WCIRDC25 December 2-5, 2026 @hiltonuniversal
Los Angeles, CA
Joined January 2011
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World Congress on IR, DM & CVD π retweeted
#WCIRDC2025
Congratulations to Dr Tracey McLaughlin from @StanfordMed for receiving the Gerald Reaven Distinguished Leader in Insulin Resistance award at @WCIRDC!
Superb choice and great lecture!ππ
@GoHealio @HeartinDiabetes @YHandelsmanMD @MIOAmerica
World Congress on IR, DM & CVD π retweeted
Continuous glucose monitoring may have a role in identifying and preventing diabetes among healthy adults, but more studies in people without diabetes need to be conducted, according to a speaker at #WCIRDC25
healio.com/news/endocrinologβ¦
@WCIRDC @YHandelsmanMD
World Congress on IR, DM & CVD π retweeted
#JCDD #PartnerConferences
22nd Annual World Congress on Insulin Resistance, Diabetes & Cardiovascular Disease (WCIRDC)
π
12β14 December 2024
π Hilton Universal City Hotel, Los Angeles, CA
πmdpi.com/journal/jcdd/eventsβ¦
World Congress on IR, DM & CVD π retweeted
I still don't understand why colchicine continues to be disrespected - three positive outcome studies and CCTA plaque studies showing benefit, all for a 2a recommendation? sciencedirect.com/science/arβ¦
World Congress on IR, DM & CVD π retweeted
Breaking: Abstract from the 21st @WCIRDC Hits 1M Views! π @BudoffMd presents groundbreaking research on the #KetogenicDiet. The #KETO Trial explores carbohydrate restriction-induced elevations in #LDL-cholesterol and #atherosclerosis. Watch now! teapaw.org/realDaveFeldman/statusβ¦
π¨π¨π¨π¨π¨π¨π¨π¨
BREAKING: @BudoffMd has now presented the matched analysis for:
KETO (#LMHRstudy) vs Control (#MiHeart)
-πPlease RTπ-
METHODS βΒ 80 Participants of #LMHRstudy fell within #MiHeart age range and were then matched 1:1 for age, gender, race, diabetes mellitus, hyperlipidemia, hypertension, and past smoking to asymptomatic subjects from the #MiHeart cohort.
PRIMARY ANALYSIS βΒ High resolution heart scans (#CCTA) allowing for primary analysis of Total Plaque Score (TPS), Total Stenosis Score (TSS) and Segment Involvement Score (SIS)
RESULTS
The matched mean age was 55.5 years, with mean #LDL cholesterol of 272 mg/dL (max LDL-C 591) mg/dl and mean 4.7 years duration on a ketogenic diet.
π¨ There was no significant difference in coronary plaque burden of #LMHRstudy (mean LDL-C 272) cohort as compared to #MiHeart controls (mean LDL 123 mg/dl); nb: pre-KETO LDL-C in KETO group was 122 mg/dl
π¨ There was no significant difference in CAC (median and IQR) [0 (0,56)] versus [1 (0, 49)], p = 0.520
π¨ No relationship of LDL-C elevations and plaque
β οΈ This analysis is on baseline scans and the study is still ongoing for second CCTA completion in our cohort by February of 2024. And as always, please continue to work with your doctor.
- I will have my own video reaction and thoughts in the coming hours.
πππ to everyone -- and I mean everyone -- who helped us get to this pivotal milestone. πππ
World Congress on IR, DM & CVD π retweeted
The @AHAScience #AHAWIC Committee is highlighting issues related to women's cardiovascular health during #HeartMonth
Conditions that occur during pregnancy impact future CV risk.
#GoRed #KnowYourRisk
@noshreza @ErinMichos @ASPCardio @MonSangh @WomenAs1 @WHA @TheFHFoundation
World Congress on IR, DM & CVD π retweeted
World Congress on IR, DM & CVD π retweeted
Bravo! Love seeing one giant, @JoslinDiabetesβ Prof Ron Kahn, celebrated by another giant, @UofTβs Prof @DanielJDrucker. Happy birthday, Dr Kahn (the great!) β¦ + TY both (ital) for all you have done, are doing, and will do for people w/diabetes, pre-diabetes, + obesity. π β at San Francisco, CA
Happy (80th!) Birthday to Professor Ron Kahn, a pioneer in the molecular mechanisms of #insulin action #diabetes @JoslinDiabetes @harvardmed @theNASciences @AmDiabetesAssn @JDRF @NIDDKgov @diabetesmaster @jclinicalinvest @the_asci
World Congress on IR, DM & CVD π retweeted
π₯#CME Alert! Cardiologists, here's your chance to explore "Hot Topics in Cardiovascular Disease: Improving Outcomes in Type 2 Diabetes" at medscape.org/viewarticle/992β¦.
Earn up to 1.25 AMA PRA Category 1 Credits! Available until 6/1/2024.
@_brendan_ #CardioEd #Diabetes #CVOTs #CVD
World Congress on IR, DM & CVD π retweeted
Replying to @AniaJastreboff
@AniaJastreboff, professor of medicine at @YaleMed, shared insights on the evolving landscape of obesity treatment during the recent @WCIRDC, emphasizing the importance of moving beyond just weight reduction. Read more at @EndocrineToday: healio.com/news/endocrinologβ¦
@YalePediatrics
World Congress on IR, DM & CVD π retweeted
Replying to @DrNathanWong
@DrNathanWong, Professor and Director at @UCIrvine, addressed the global diabetes epidemic and its repercussions on cardiovascular health during the recent @WCIRDC. Explore the full article on @EndocrineToday at healio.com/news/endocrinologβ¦
@Healio @CardiologyToday @UCI_Cardiology
World Congress on IR, DM & CVD π retweeted
Replying to @liver4kids
@liver4kids, Chief of Gastroenterology at @ChildrensLA, discussed at the 21st @WCIRDC how post-#BariatricSurgery weight loss elevates bile acid levels, suggesting potential therapies for #NASH, such as targeting the #FXR
Explore @EndocrineToday's article: healio.com/news/endocrinologβ¦
World Congress on IR, DM & CVD π retweeted
Will the new and emerging therapeutic approaches described control hypertension and reduce disparities? Perhaps, but we must use the tools and methods we have now and apply newer therapies withΒ equity in mind. @GoHealio
healio.com/news/cardiology/2β¦
World Congress on IR, DM & CVD π retweeted
With new anti-obesity medications now inducing greater weight loss for people with #obesity, providers need to aim for improving other parts of their patientsβ health outside of body weight, according to @AniaJasreboff at #WCIRDC23. @WCIRDC
Read more π
healio.com/news/endocrinologβ¦
World Congress on IR, DM & CVD π retweeted
At #WCIRDC23, @MkosiborodMD reviews some of the key CV outcome trials from 2023, including STEP-HFpEF, SELECT, CLEAR Outcomes and DAPA-MI @YHandelsmanMD @WCIRDC #WCIRDC23 @EndocrineToday @GoHealio #Cardiotwitter @UMKCmedschool
Read more π
healio.com/news/cardiology/2β¦
World Congress on IR, DM & CVD π retweeted
Grateful for the immense support and generosity of our sponsors and faculty at the 21st @WCIRDC. Your commitment and contribution made this conference a resounding success! Thank you for being part of our journey in advancing #InsulinResistance, #Diabetes, #Obesity, and #CRM.
World Congress on IR, DM & CVD π retweeted
Unveiling the latest Multispecialty Practice Recommendations from the @DCMinstitute was a key highlight at the 21st @WCIRDC. This collaborative update from global experts offers vital guidance for healthcare providers worldwide.
@Medriva's full article: medriva.com/health/healthcarβ¦
World Congress on IR, DM & CVD π retweeted
Proud to support @WCIRDC under the leadership of @YHandelsmanMD and so many others as we work together, to improve the care of patients with diabetes and metabolic conditions!
This past weekend, Esperion was recognized at the 21st Annual @WCIRDC for important contributions to the Science of Lipids and the Prevention of #Atherosclerosis and #HeartDisease.
π
π«
#DrivingWhatsNext #wcirdc23
@YHandelsmanMD @bicoastalPAC
World Congress on IR, DM & CVD π retweeted
Whoa -- whoa!
π₯About to hit 1 million in 1 weekπ₯
See @BudoffMd's award winning presentation (#LMHRstudy) - vs matched control (#MiHeart)
βοΈ #LDL 272 (4.7 yrs) vs 123
β
No statistically sig difference in plaque
β
No correlation of plaque w/ #LDL
β οΈ More research needed β οΈ
π¨π¨π¨π¨π¨π¨π¨π¨
BREAKING: @BudoffMd has now presented the matched analysis for:
KETO (#LMHRstudy) vs Control (#MiHeart)
-πPlease RTπ-
METHODS βΒ 80 Participants of #LMHRstudy fell within #MiHeart age range and were then matched 1:1 for age, gender, race, diabetes mellitus, hyperlipidemia, hypertension, and past smoking to asymptomatic subjects from the #MiHeart cohort.
PRIMARY ANALYSIS βΒ High resolution heart scans (#CCTA) allowing for primary analysis of Total Plaque Score (TPS), Total Stenosis Score (TSS) and Segment Involvement Score (SIS)
RESULTS
The matched mean age was 55.5 years, with mean #LDL cholesterol of 272 mg/dL (max LDL-C 591) mg/dl and mean 4.7 years duration on a ketogenic diet.
π¨ There was no significant difference in coronary plaque burden of #LMHRstudy (mean LDL-C 272) cohort as compared to #MiHeart controls (mean LDL 123 mg/dl); nb: pre-KETO LDL-C in KETO group was 122 mg/dl
π¨ There was no significant difference in CAC (median and IQR) [0 (0,56)] versus [1 (0, 49)], p = 0.520
π¨ No relationship of LDL-C elevations and plaque
β οΈ This analysis is on baseline scans and the study is still ongoing for second CCTA completion in our cohort by February of 2024. And as always, please continue to work with your doctor.
- I will have my own video reaction and thoughts in the coming hours.
πππ to everyone -- and I mean everyone -- who helped us get to this pivotal milestone. πππ









































