A DNA Nanomaterials lab @BIOENGatIL, @ChemistryUIUC, @IGBIllinois, MNTL-UIUC, @Illinois_Alma with applications in biosensing and medicine. DNA Star builders.
Urbana-Champaign, Illinois
Joined November 2019
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Xing Wang Research Group retweeted
Check out our model of how homology search in mammalian cells may be aided by a motor protein! A link for free access to the paper can be found here. tjhalab.com/the-lab
Thrilled to share that my postdoc research is published today in @ScienceMagazine !! We found that DNA repair uses cohesin to build chromatin loops that guide the homology search and boost accurate repair! 1/n
science.org/doi/10.1126/scie…
Xing Wang Research Group retweeted
I spent 1.5 years at MIT co-designing a new undergrad program in Genetic Engineering.
The full report is now publicly available. It describes what needs to be built to educate the next generation, and why.
Appendix II includes notes from interviews with 100+ biotech company CEOs and scientists about what they look for in new hires.
Appendix III includes a huge analysis of all existing curricula in biotechnology and genetic engineering globally. It also features dozens of photos from my visits to biotechnology centers across the U.S., Europe, and Asia.
Hopefully this will be a useful resource for educators looking to adapt or expand their curriculums, too.
Xing Wang Research Group retweeted
A team at the Broad Institute co-led by @Sarah_E_Pierce, @stevenerwood, and @davidrliu has developed a new genome-editing strategy that could potentially lead to a one-time treatment for multiple unrelated genetic diseases. broad.io/PERTNews
ALT A graphic displaying an oval containing a DNA double helix with several base pairs highlighted, connected to four icons representing patients.
Xing Wang Research Group retweeted
DNA Nanostructure Self-Assembly in an Aqueous Ionic Liquid Solution with Enhanced Stability and Target Binding Affinity | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/jac…
Xing Wang Research Group retweeted
Our work on using aqueous ionic liquids for DNA Nanostructure assembly with enhanced stability and target binding. Thanks to support from all the authors for making this happen! @XingWangGroup @arunrichardc @J_A_C_S @UofIllinois @BIOENGatIL
DNA Nanostructure Self-Assembly in an Aqueous Ionic Liquid Solution with Enhanced Stability and Target Binding Affinity | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/jac…
Xing Wang Research Group retweeted
Our 2nd paper of the week is now live! Happy to be part of this work led by @DGandavadi in @XingWangGroup, with support from Hannah and @aarodg from our group.
Check it out here: bit.ly/3JKwgqM
Xing Wang Research Group retweeted
As a follow-up to our CLEAN tool, we developed EZSpecificity to predict enzyme substrate specificity from sequence (nature.com/articles/s41586-0…) in collaboration with @diwakarshukla and his team. See news: news.illinois.edu/new-ai-too…
Xing Wang Research Group retweeted
Spatial-DMT is now published in @Nature ! For the first time, we can simultaneously map DNA methylation and RNA transcription in tissue context. Great collab with @zhouwanding lab. Big congrats to Chin @Chin72155594 , Hongxiang @HongxiangFu and team! nature.com/articles/s41586-0…
Xing Wang Research Group retweeted
Multiple faculty positions open in RNA science at UF Scripps (Asst/Assoc/Full Prof) in Jupiter, FL—part of a major investment in RNA research.
Apply: jobs.sciencecareers.org/job/…
Center info: wertheim.scripps.ufl.edu/rna…
Please retweet!
Xing Wang Research Group retweeted
Targeted delivery of diverse biomolecules with engineered bacterial nanosyringes go.nature.com/46OFcoj
Xing Wang Research Group retweeted
Great to see this is now out in @NatureNano! Thanks to @leonard_prins for this (yet another) collaborative project...kudos to @erica_delgrosso and Ben Roberts for combining experiment and theory in such a nice way. Thanks also to @EPenocchio for help with the theoretical part!
New paper online:
An information ratchet improves selectivity in molecular recognition under non-equilibrium conditions.
"...mechanism increases selectivity for the correct DNA duplex from 2:1 at equilibrium to 6:1 under energy-dissipating conditions."
nature.com/articles/s41565-0…
Xing Wang Research Group retweeted
pubs.acs.org/doi/full/10.102… Photonic Crystal Grating Resonance and Interfaces for Health Diagnostic Technologies An added advantage of accessibility and convenience of these technologies stemming from integrating smartphone-based detection is succinctly captured. #havanasyndrome studies
Xing Wang Research Group retweeted
In Science, researchers present a new method to safely and preferentially generate CAR T cells directly inside the body using targeted lipid nanoparticles that deliver mRNA directly to T cells.
The approach showed rapid and sustained immune reprogramming in preclinical models, highlighting its promise for treating cancer and autoimmune diseases.
📄: scim.ag/3TuHwJ3
#SciencePerspective: scim.ag/3SXG15Z
ALT Graphic depicting in vivo generation of CAR T cells
Xing Wang Research Group retweeted
engineering T cells within the body of the patient (rather than in a lab) is the next frontier for cancer immunotherapy
Xing Wang Research Group retweeted
My new invited review in @ChemCommun discusses the strategies used for isothermal assembly of DNA nanostructures. Check it out!
@RoySocChem @TheRNAInstitute @CNSE
Xing Wang Research Group retweeted
A new @SciRobotics study highlights how an insect-inspired leg design and control strategy allows the @Harvard RoboBee to execute safe, controlled, and accurate landings as it flies between the leaves of a plant. scim.ag/3RTTISW
Xing Wang Research Group retweeted
A chemical toolbox for surface engineering of extracellular vesicles bit.ly/3YIZevl
