Postdoc in @kartikpattabir1 and Sestan labs @yale | formerly PhD student in @kwanlab @umich
Joined April 2018
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Excited to share our new preprint where we find chromatin remodeler Arid1a mediates cortical circuit development through a selective role in subplate neurons!
Our new preprint! Subplate neurons orchestrate developmental assembly of cortical circuits. We find an unexpectedly selective role for ubiquitous chromatin remodeler Arid1a in subplate neuron identity & circuit wiring!🎉 1/
biorxiv.org/content/10.1101/…
Dan Doyle retweeted
#FluorescenceFriday: #SmartSPIM video from the Pattabiraman Lab (@Yale)! #GFP (green) & #TranssynapticTracing (red) reveal prefrontal cortex & thalamus connectivity in a neonatal mouse brain.
Full video & details: bit.ly/3UUwKx0 Thanks to @kartikpattabir1 @_dan_doyle
Dan Doyle retweeted
Thank you to the Deeda Blair research initiative and the FNIH for the support! Excited for the opportunity to pursue a new avenue of testing epigenetic editing based approaches to alter the neurodevelopmental trajectory of schizophrenia. @YaleCSC @WuTsaiYale
The FNIH proudly announces three new recipients of the Deeda Blair Research Initiative for Disorders of the Brain award. This initiative aims to revolutionize the diagnosis and treatment of brain disorders, bringing new hope to millions worldwide. Congratulations to this year's the awardees: Ryan Ash, MD, PhD, of @Stanford; Andrew Moses Lee, MD, PhD, of @UCSF ; and Kartik Pattabiraman, MD, PhD, of @Yale.
Learn more about this initiative and the incredible work it supports here: fnih.org/our-programs/poweri…
Dan Doyle retweeted
Our H3.3 paper is now out in print at PNAS @PNASNews 🎉🎉🎉
Congrats to Owen Funk @DrFunk_PhD and team!!! 12/11
pnas.org/doi/10.1073/pnas.21…
Dan Doyle retweeted
Excited to share our latest preprint! 🎉 In this study, we find that the histone H3 variant H3.3 establishes neuronal transcriptome, identity, and connectivity during a critical window in cerebral cortex development. 1/11
biorxiv.org/content/10.1101/…
Dan Doyle retweeted
Huge congratulations to @kwanlab for receiving tenure & promotion to Associate Professor in Human Genetics & Associate Res. Professor in the Michigan Neuroscience Institute! Delighted for this awesome colleague who makes beautiful science! @SequenceMan @Henrypaulson5 @Flagel_Lab
Dan Doyle retweeted
We are thrilled that our paper on chromatin remodeler Arid1a and subplate-dependent circuit wiring is now published in PNAS @PNASNews 🎉
Congrats to lead author @_Dan_Doyle and @kwanlab co-authors!
pnas.org/content/118/21/e210…
Our new preprint! Subplate neurons orchestrate developmental assembly of cortical circuits. We find an unexpectedly selective role for ubiquitous chromatin remodeler Arid1a in subplate neuron identity & circuit wiring!🎉 1/
biorxiv.org/content/10.1101/…
Dan Doyle retweeted
UCSC Cell Browser, developed by Jim Kent and Max Haeussler - amazing resource for easy browsing of dozens of single cell datasets out there! I use it every day!
Dan Doyle retweeted
Want to learn more about the Neuro Grad Program @NGPMichigan ? Join us for a virtual open house event today at 6-8PM EST, RSVP here bit.ly/ngpvirtual.
Please RT and tell your students about it 🥰 thx!
Dan Doyle retweeted
2020 Chemistry Laureates Emmanuelle Charpentier and Jennifer Doudna discovered one of gene technology’s sharpest tools: the CRISPR/Cas9 genetic scissors. Using these, researchers can change the DNA of animals, plants and microorganisms with extremely high precision.
#NobelPrize
Dan Doyle retweeted
Our 1st University of Michigan #Neuroscience Graduate Program @NGPMichigan virtual open house is Friday, October 9th. You must register bit.ly/ngpvirtual ahead of time. Come chat with us about our program and the application process! #BlackInNeuro @sacnas @ABRCMS Please RT.
Considering graduate programs in #neuroscience? Come to our virtual @NGPMichigan open house, Oct. 9th & 15th, to meet some of our students and faculty, hear about our program, learn about the admissions process, and get your questions answered. Register👉: bit.ly/ngpvirtual
Dan Doyle retweeted
Considering graduate programs in #neuroscience? Come to our virtual @NGPMichigan open house, Oct. 9th & 15th, to meet some of our students and faculty, hear about our program, learn about the admissions process, and get your questions answered. Register👉: bit.ly/ngpvirtual
Check out our new paper from @kwanlab!
Thrilled to share our new paper @NatureComms! 🎉
Chromatin regulates transcription, but it also mediates DNA repair. Here, we uncover molecularly distinct roles for chromatin remodeler Ino80 in gene regulation and genome maintenance in corticogenesis. 1/
ift.tt/3gfESSt
Dan Doyle retweeted
Dave Richard from @stonybrooku telling us about his work in the @kwanlab investigating epigenetic regulation of cortical development. @NGPMichigan1
Dan Doyle retweeted
Excited to share our paper @NatureComms!
Here, we manipulate brain somatic genome stability by Knl1 deletion from neural progenitors (NPCs), which disrupts the spindle assembly checkpoint that safeguards against chromosome missegregation and aneuploidy. 1/
nature.com/articles/s41467-0…