Co-founder, CSO @weave_bio, Former CAO @Sloan_Kettering. Torah, science, complexity and emergence. (maybe a bit of bball analytics...)
New Haven, CT
Joined March 2009
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I haven't been active on X for a few years now. But I decided to give it another try today.
The first thing I saw upon logging in was an exchange between two otherwise intelligent, knowledgeable scholars who were resorting to name-calling and ad hominem attacks in a debate over linguistics.
Sigh...
teapaw.org/elongilad/status/20342…
Ari Caroline retweeted
THE IDEAL LIFE
A Short Film
Larry Caroline came of age in the height of the 60's counterculture milieu, quickly becoming a vocal part of the civil rights and anti-war movements
As a young assistant professor at the University of Texas, he called for a "revolution," which quickly resulted in headlines and losing his career
After moving to Buffalo with his wife, Larry found himself drawn to a different counterculture, this one in the small Chabad House set up by Rabbi Nosson Gurary. Slowly but surely, Larry became lovingly known as 'Reb Yisroel," after his given Jewish name
When they moved to Philadelphia, 'Reb Yisroel' took a position at Beth Jacob Schools where he soon became responsible for the school's shaky finances after the director's untimely passing
Despite these hardships and in opposition to a group of vocal parents, Larry insisted on accepting the children of Russian immigrants who couldn't afford to pay but would now have their first encounter with their heritage
Years later, Larry was asked to reflect on his choices and the consequences of the idealism that led him to make them
Produced for his Shloshim, 18 Kislev 5786
Let’s go Ross!
Dr. Ross Levine (@rosslevinemd), Senior Vice President of Translational Research at MSK, has been named MSK's new Chief Scientific Officer (CSO).
Dr. Levine will be responsible for setting and leading strategy for basic and translational research, including programs, centers, and technology cores.
Congratulations, Dr. Levine!
bit.ly/4nQAeNj
Ari Caroline retweeted
Regulatory workflows are the backbone of drug development. Weave isn't solving a nice-to-have problem—they're eliminating the critical bottleneck between breakthrough science and patient access.
@GroundUpVC is proud to have led the company's pre-seed and been with them from day one. Congratulations to Brandon Rice, @aricaroline and Umut Eser on this milestone. Excited to welcome @USVP_ on board as the Series A lead and extremely bullish on what this means for the future of getting life-changing drugs to patients faster.
In a market flooded with AI buzzwords, Weave is solving one of drug development's most critical bottlenecks: regulatory workflows that determine how quickly life-changing therapies reach patients.
Today, we're proud to announce our $20M Series A, led by @USVP_ , with participation from @iendeavors, @magneticvc, @trailmixvc , @CharacterVC, and Serrado Capital.
This isn't just about technology—it's about impact:
✅ Accelerating regulatory timelines by 50%+
✅ Expanding across the full therapeutic lifecycle (IND to NDA to post-market)
✅ Scaling globally to serve drug developers worldwide
What sets us apart? We're AI-native by design, not by rebranding. Our platform delivers speed, accuracy, and compliance—powered by AI, validated by human expertise.
The future of regulatory workflows is here. And it's built on substance, not hype.
👉Read the full announcement: businesswire.com/news/home/2…
#WeaveBio #SeriesA #DrugDevelopment #RegulatoryInnovation #AIinPharma #Biotech #LifeSciences
Ari Caroline retweeted
🔹 Weave Wednesday 🔹
What if creating a Clinical Study Report didn’t take days—or weeks?
💡 With The Weave Platform, it can take just one hour.
We’re showing how structured data and human-driven automation come together to accelerate regulatory workflows—without cutting corners.
Watch how it works—and imagine reclaiming time for what really matters.
Interested in a custom demo? Book here: app.hubspot.com/pages/233282…
#WeaveWednesday #ClinicalStudyReport #RegulatoryWorkflows #Biotech #Pharma #AutoIND #WeavePlatform
Ari Caroline retweeted
what a privilege it was to know @atulbutte. they say never meet your heroes, but Atul was the exception.
i’ve relentlessly followed his path: first eight years at Brown, now at Boston Children’s. he was there every step of the way. his work shaped how I think about computation and medicine. his heart showed me something even more profound—that brilliance and generosity work best together.
to be mentored by Atul was one of life’s greatest gifts. he was incisive, generous, and unflinchingly honest about what it takes to do work that matters. he held high standards for both science and purpose. conversations with him would fuel curiosity for months.
Atul sought truth. he challenged assumptions. he didn’t chase trends, he set them. he brought urgency. he quietly built the blueprint for the future of computational medicine, and always brought others with him.
he spoke clearly, thought boldly, and listened deeply. supportive, kind, patient, open-armed. Atul led with conviction and joy.
his passing is a profound loss. but the outpouring of love from the lives he touched reminds us just how rare his presence was.
Atul, in our last lunch, you were as passionate as ever about where our field is heading and what it means for patients. that spark and sense of what’s possible is what I’ll carry forward.
Rest in peace, Atul Butte. you changed medicine. and you changed me.
i’ll leave these words you left us—a small part of your vision for the next hundred years of medicine:
Ari Caroline retweeted
Although Atul was always at the cutting edge of science he had the presence and expansive outlook of the intellectual giants of the previous century. His integrative approach to biomedicine has inspired thousands. But first he loved his family and friends with an enthusiasm that brought joy to all of us.
Ari Caroline retweeted
Heartbroken to share my mentor & friend Dr. Atul J. Butte @atulbutte has passed.
He saw potential in me and turned it into opportunity-- for me, and so many others.
We bonded over Star Trek and he was our Captain.
Picard’s parting toast in his honor, final episode: “....five-card stud, nothing wild… and the sky’s the limit.”
youtu.be/mt3MVP3FizQ?si=JRuH…
Ari Caroline retweeted
There are few in this world who were such forces for good as @atulbutte. His dazzling intellect, relentless curiosity, generosity of spirit, boundless charisma, and infinite optimism left a mark on everything he touched and everyone lucky enough to know him. An enormous loss.
Ari Caroline retweeted
Saddened to hear the loss of our brother @atulbutte. He inspired many to join in his call to realize the full benefits of open health data. He was a dear friend I could call upon to serve as an early adopter, to share feedback on my often crazy ideas :). We love you, bhaiyya💔🙏🏼
Ari Caroline retweeted
Atul was a visionary whose infectious enthusiasm will live on and power the generations. We will miss you, Friend.
Between alarms and sheltering, I learned last night that my postdoc mentor, Professor Atul Butte @atulbutte, has passed away, and he is only 55 years old. This is devastating news 💔.
Atul was a giant in so many ways. He was a visionary leader in translational bioinformatics @Stanford who reinvented himself as a pioneer of AI in medicine @UCSF. He published hundreds of papers, founded multiple companies, was elected to the National Academy of Medicine, and recently to the American Academy of Arts & Sciences.
But Atul was much more than his achievements. He possessed something rare in science - infectious positivity. Every encounter with him, no matter how low I felt going in, I'd leave optimistic and energized to pursue my goals. After every talk he gave, students would line up to tell him how he motivated them to do something big with their lives.
Another rare trait was his kindness and generosity with credit. Atul taught me: "credit is indefinitely divisible." In a field where people often take undeserved credit, this was inspiring.
I will miss Atul, like so many others will. He is survived by his wife Gini and daughter Kimi, but his legacy will live on through his countless trainees and colleagues worldwide.
RT @weave_bio: Sneak Peek Alert: AutoCT at SCT 2025
Headed to Vancouver for the @SCTorg Society for Clinical Trials meeting on May 19–20?…
Ari Caroline retweeted
🤔 FDA guidances are essentially complex prompts—but written for human regulatory writers.
These documents can span 30-40 pages, packed with intricate decision trees, dense terminology, and complex tables. An expert writer might need to cross-reference 10-20 study reports just to handle one calculation.
At Weave, we’re building a neuro-symbolic framework powered by Llama4 to tackle exactly these high-level reasoning challenges. @AIatMeta's Llama4 helps us parse regulatory documents, generate precise computational graphs, and dynamically build robust drug development ontologies.
👉 Our Co-founder and Chief AI Officer, @Umut1Eser Eser, will be at #LlamaCon2025 tomorrow. Interested in learning more? Connect with him there!
Ari Caroline retweeted
This week’s #WeaveWednesday insight comes from Dani Bergey, Sr. Product Designer — designing clear, human-centered experiences in a world full of complexity:
At Weave, we learned early on that traditional regulatory workflows in drug development are a maze of complexity: multiple teams, writers, review processes, and disconnected software systems. Not only does this create a poor experience, but it leads to wasted time, submission delays, and loads of frustration.
Yes, getting a drug through clinical trials should require meticulous attention and many expert eyes. But the rigor of the process shouldn’t mean complexity for everyone involved.
We stepped back — way back — and distilled this complex workflow into three intuitive spaces: the Data Room, the Dossier, and the Editor. Every user need we’ve uncovered fits nicely into one of these three environments.
Better yet, we’ve strategically infused AI throughout these spaces to eliminate more extraneous complexity while keeping you firmly in control:
☑️ Looking for a specific plot buried in thousands of pages of drug data? Our Deep Search and Explore tools in the Data Room can find it quickly.
☑️ Want to get your first drafts prepared for your team to dive into? Jump into AI templates and generate content from the Dossier.
☑️ Want to incorporate additional source data into your documents?Use advanced Refinement features in the Editor.
Drug development will always be complex — but your workflow shouldn’t be. It’s time for a simpler path forward.
Visit weave.bio to learn more.
#ClinicalTrials #RegulatoryAffairs #INDSubmissions #Innovation
Ari Caroline retweeted
🤔 Can AI Make IND Applications Less Tedious? The Scientist Asks—Weave Is Proving It Can.
IND applications are a critical step in bringing new therapies to patients, but the process is anything but simple. Managing massive amounts of data, ensuring accuracy, and meeting tight deadlines can overwhelm even the most experienced teams.
That’s why @TheScientistLLC is asking: Can AI help? At Weave, we know the answer—because we’re already making it happen with #AutoIND.
AI is changing the game, and Weave is at the forefront of this transformation. Our AI-native platform is built to streamline regulatory workflows, enabling teams to:
✅ Automate Drafting & Data Organization – Reduce manual effort while improving consistency
✅ Enhance Accuracy & Traceability – Keep every submission sourced, structured, and audit-ready
✅ Accelerate Submission Timelines – Free up experts to focus on strategy, not paperwork
🔗 Read the full article: the-scientist.com/ind-applic…
Discover how Weave and AutoIND can transform your regulatory workflows: weave.bio
#RegulatoryAI #LifeSciences #INDSubmissions #WeaveTheFuture
Ari Caroline retweeted
Just back from our #Weave corporate retreat—refreshed, refocused, and more connected than ever. A huge thank you to our leadership team: @aricaroline, @Umut1Eser, Brandon Rice, @levi_malott, Sean Campbell, and @LinMateo for bringing this incredible team together!
In-person time is invaluable—it strengthens collaboration, fuels innovation, and reminds us why what we do matters. For our customers, that means a team that’s even more aligned, energized, and ready to make regulatory processes smoother and more efficient. Stronger together, stronger for you.
Ari Caroline retweeted
Mastering the Art of Prompting: How to Get LLMs to Do Exactly What You Want
🗓 Thursday, April 17, 2025 | ⏰ Noon EST / 9 AM PST
As a leader in AI-driven solutions, Weave is transforming how teams interact with Large Language Models (LLMs). But even the most advanced AI is only as effective as the prompts it receives.
Join us for an in-depth webinar, where our Chief AI Officer, Umut Eser, will break down:
✅ The anatomy of an effective prompt – clarity, context, and structure
✅ Advanced techniques – Chain-of-Thought and Few-Shot learning
✅ Real-world applications – regulatory submissions, clinical documentation, and corporate workflows
Whether you’re streamlining submissions, optimizing documentation, or enhancing AI-driven decision-making, this session will give you actionable strategies to drive better outcomes.
🔗 Reserve your spot today! lnkd.in/grHHgsiy
Ari Caroline retweeted
Meet Wes Galliher: A Key Weaver 🌟
At Weave, our small but mighty team of Weavers drives our success. Today, we’re spotlighting @wesgalliher, our dedicated Staff Product Manager!
Wes plays a vital role in shaping our regulatory automation platform, working closely with prospects & customers to ensure an exceptional user experience.
Outside work, he’s a devoted family man, who dreams of working remote from a coffee shop in Tuscany. He finds inspiration in his Christian faith & wishes for the superpower of time travel to meet historical figures.
Join us in celebrating Wes & his impact at Weave! 🙌
#Weave #Weavers #TeamSpotlight
Ari Caroline retweeted
I decided to write a much longer post on this.
Essentially, they apply a flawed MAD analogy to MAIM and overestimate the certainty of retaliatory sabotage while underestimating the destabilizing effects of a breakthrough. I call this the “Jackpot Jinx.”
This miscalculation of payoffs, combined with factors like uncertainty, subjective triggers, and asymmetric capabilities, creates an unstable framework that incentivizes reckless, aggressive actions rather than ensuring stable deterrence. 👇
Superintelligence is destabilizing.
If China were on the cusp of building it first, Russia or the US would not sit idly by—they'd potentially threaten cyberattacks to deter its creation.
@ericschmidt @alexandr_wang and I propose a new strategy for superintelligence. 🧵
Ari Caroline retweeted
Tagging source docs is just half the picture—the real power is using those tags to place the right data in the right eCTD docs. #AutoIND makes it seamless with templates!
⚡ Pre-built, customizable templates
⚡ Quick tag edits in seconds
⚡ Automated integration into drafts
⚡ Precision mapping at any level
⚡ Built-in consistency across dossiers
🔍 Want to see it in action?
🎥 Watch the video below
🌐 Visit weave.bio
📩 Contact us at [email protected]
#WeaveBio #AutoIND #DataTagging #RegulatoryTech #WeaveWednesday