Kidney Cancer surgeon/scientist @MSKCancerCenter . Co-leader of Translational Kidney Cancer Program and Assistant PD @urologymsk Tweets my own.

Joined February 2009
ari hakimi retweeted
Want to learn about the the largest and oldest @UroOnc fellowship? Sign up for our virtual open house on Nov 11th at 7 pm. Hear from our PD and current fellows about our mix of open and MIS surgery, unparalleled research opportunities and mentorship. forms.gle/Gdf4RntMQefHvhwKA
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ari hakimi retweeted
After many years of effort, deliberation, excitement, angst, joy, and Wednesday afternoon lab lunches, our group's first manuscript on cachexia, led by Venise Jan Castillon, Amy Xie, and really our whole lab nature.com/articles/s41591-0… @NatureMedicine
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ari hakimi retweeted
Incredibly excited to report today on the determinants of toxicity to systemic therapy in cancer patients. Led by many including Alex Guo, Feiyang Huang, Saksham Mohan, River Walser, and the fearless @ZiadBakouny. Co-led by Wes Tansey and Jian Carrot-Zhang medrxiv.org/content/10.64898…
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Honored to be a visiting professor at MSKCC today. 11 years ago I graduated from @MSKCancerCenter. Spent 5.5 yrs at @UMichRadOnc and been chair for about 5.5 yrs at @UHhospitals @RadOncUH @cwru. Very nostalgic coming back to where my radonc journey started and loved my time here! Hope I made MSK proud. @HimanshuNagarMD @seanmmcbride @rtdess @RadOncDocJ @AmarUKishan @neerajaiims @TylerSbrt @alison_tree @SbrtSean @DrAndrewLoblaw @urotoday @ndesai2005 @JohnCuaron
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ari hakimi retweeted
In our latest, we continued multi-omic exploration of GI neuroendocrine tumors, finding potential organ-specific molecular programs and microenvironmental niches - congrats Julie Karam @SamHoffmanMed et al! @DanaFarber @broadinstitute @jclinicalinvest jci.org/articles/view/204119
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ari hakimi retweeted
Replying to @arihakimi
@arihakimi joins us with Lyn Voung to discuss a recent #cancercell paper which explored the impact of TKI-induced hypoxia in their RCC mouse model. spotifycreators-web.app.link…
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Wonderful evening with our amazing @UroOnc fellows and families. Lots of little babies!!
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Great time at @kidneycan meeting talking science and collaborations with experts from all over! #kcrs26
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ari hakimi retweeted
Love this start to #KCRS26 from Craig Thompson @MSKCancerCenter. Bonus: 👋 hi from the mural from me and @UrologyMSK/@AmerUrological USMART Program mentor @AriHakimi
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Amazing keynote from Craig Thompson from @MSKCancerCenter to lead of the @kidneycan meeting!
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Best meeting of the year!!
The night before #KCRS26, The premier meeting of Kidney Cancer Research @kidneycan @HHammersMD @DrRanaMcKay @arihakimi @montypal
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The night before #KCRS26, The premier meeting of Kidney Cancer Research @kidneycan @HHammersMD @DrRanaMcKay @arihakimi @montypal
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ari hakimi retweeted
Excited to share our review in @NatRevUrol “Urolithiasis in Patients with Cancer” @arihakimi We discuss unique mechanisms driving stone disease in cancer patients, bidirectional relationship between cancer & urolithiasis, management of urolithiasis in this pt population pubmed.ncbi.nlm.nih.gov/4233…
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Very grateful for the honor and to get to work with such a dedicated, kind and talented group of fellows. So excited for what’s to come!
Steak dinner to celebrate @arihakimi Teacher of the Year @UrologyMSK. Well deserved!
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Steak dinner to celebrate @arihakimi Teacher of the Year @UrologyMSK. Well deserved! – at Manhattan, NY
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Congratulations to Dr. Martin Weiser, who has been selected to serve serve as the next Chair of the Department of Surgery at MSK. Dr. Weiser currently holds the Stuart H.Q. Quan Chair in Colorectal Surgery, is a world-renowned academic colorectal surgeon, and has held a number of important leadership roles in his 25 years on the faculty at MSK, including serving for the past 10 months as the Acting Department Chair. Join us in welcoming Dr. Weiser to the role of Chair of the Department of Surgery by commenting below. 👏
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Across clinical trials and real-world cohorts, pretreatment hypoxia predicted poorer outcomes. In contrast, on-treatment hypoxia-associated TAM programs reflected therapeutic activity. Timing matters: baseline hypoxia and treatment-induced hypoxia are biologically distinct.
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Conclusion: ccRCC begins as a pseudohypoxic, vascular tumor. VEGFR-TKIs trigger hypoxia, driving tumor control and recruitment of SPP1⁺ TAMs. However, persistent hypoxia can ultimately promote resistance and mets linking response and failure through the same biological process.
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