Postdoc at NIH/NHLBI. PhD UNAM_MX, interested in molecular physiology. Views are my own
Bethesda, MD
Joined December 2011
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🚰 New in JASN!
Our study shows that Aqp2 transcription is not solely dependent on CREB1. Instead, any of the three CREB-family transcription factors (ATF1, CREB1, CREM) can drive vasopressin-induced AQP2 expression.
Adrian Murillo-De-Ozores retweeted
La OMS afirma que podría haberse producido una transmisión de hantavirus entre humanos en el crucero holandés donde fallecieron ya 3 pasajeros.
El virus suele transmitirse de roedores, pero en este caso, podría haberse propagado entre personas por contacto muy cercano a bordo del MV Hondius.
Ojo, el riesgo de pandemia es bajo. bbc.com/news/articles/cm2p18…
Adrian Murillo-De-Ozores retweeted
💊💉 Los sueros vitaminados son líquidos que no aportan a la salud, según el infectólogo Alejandro Macías, pues son únicamente preparaciones de agua con azúcar y alguna vitamina. Además de todo, la suministración puede ser muy peligrosa y causar muertes, como ya se vio en el caso de los cuatro fallecidos en Sonora.
Aún no se esclarece el porqué murieron cuatro personas que acudieron con el médico homeópata Maximiliano “N”, pero todos coinciden en que les inyectaron los sueros vitaminados en la clínica privada Medicina Biológica Regenerativa Celular.
Acá más detalles: radioformula.com.mx/nacional…
Adrian Murillo-De-Ozores retweeted
🚨 KEVIN O'LEARY REVELA CÓMO LE LIMPIAN LA SANGRE.
El millonario de Shark Tank habló sobre sus sesiones de filtración de sangre: extraen varios litros, los pasan por una máquina de diálisis, los ozonizan y oxigenan, y luego los regresan.
Lo hace en los Emiratos Árabes Unidos. Y jura que los beneficios se notan casi de inmediato.
Absurdo, inútil, riesgo innecesario. Se parece a ponerse sueros vitaminados, pero más costoso.
🚨 KEVIN O’LEARY JUST EXPOSED HOW THE RICH ARE SECRETLY CLEANSING THEIR BLOOD ABROADShark Tank billionaire Kevin O’Leary was filmed in Dubai openly talking about his routine blood filtration sessions — they pull out several liters, run it through a dialysis-style machine, ozonate and oxygenate it, then pump it right back in.Not a one-off experiment.
Not some experimental trial.
He says he blocks off half a day every time he’s in the UAE for it.This is already his fourth round.
And he swears the benefits hit almost immediately.The treatment isn’t FDA approved here in the States.
And you definitely won’t see it promoted on mainstream health shows.Yet the same elites who tell everyone to “trust the science” keep flying overseas to get their blood reset… then stroll out feeling brand new.Tijuana before. Dubai now.
Same playbook.What’s the first thing this makes you think of?
Adrian Murillo-De-Ozores retweeted
Beyond proud to see our latest work featured in a commentary @ScienceMagazine! 🧬 bit.ly/4rUEOv9
We set out to ask what the energy source is that powers innate immune signaling and enables "on/off" switches. 1/3
Happy to share our latest paper led by @Chen_lihe , now out in AJP-Cell!
Using a GFP reporter, we studied cell-to-cell variability in AQP2 expression and introduce a new tool to investigate the transcriptional regulation of AQP2. journals.physiology.org/doi/…
Adrian Murillo-De-Ozores retweeted
Difícil de creer que una ministra de la suprema corte, de cualquier país, considere que por haber nacido por fecundación in vitro una persona pudieran no formar parte de una familia.
En pleno Siglo XXI!
Adrian Murillo-De-Ozores retweeted
Paper alert!‼️ 🚨
So excited to share our latest work in SciAdv done at the UFM in collaboration with DarioAlessi, @dhekidney, Delpirelab.
➡️science.org/doi/10.1126/scia…
🧂How can a psudokinase and scaffolding proteins modulate Na+ transport in the kidney?
A thread 🧵
CRISPR + RNA-seq reveal overlapping roles of CREB-family transcription factors in regulating Aqp2 gene transcription.
Proud to contribute from NHLBI with Dr. Knepper & team.
🔗 journals.lww.com/jasn/abstra…
Adrian Murillo-De-Ozores retweeted
"The results from this study, together with earlier studies, provide insights into the heterogeneity of DCT cells and their functional characteristics." This Editorial examines a study that profiles gene expression in the cells of distal convoluted tubule bit.ly/JASN0330
Adrian Murillo-De-Ozores retweeted
We wrote a review about the phosphatases that regulate the NaCl cotransporter in the kidney! ncbi.nlm.nih.gov/pmc/article… Here, we tried to summarize many people’s insights into some regulatory mechanisms of NaCl reabsorption. Many questions still remain. Hope you like it!
Adrian Murillo-De-Ozores retweeted
Proud also that our paper on WNK4 modulation by potassium came out in November issue of KI also with a cool editorial wrote by Hoorn and @jeroendebaaij. Great work by María Castañeda-Bueno!
Multiple molecular mechanisms are involved in the activation of the kidney NaCl cotransporter by #hypokalemia
doi.org/10.1016/j.kint.2022.…
@armurillo64 @hectorcarbajalc @gerardo_gamba
Adrian Murillo-De-Ozores retweeted
Looking for evidence that biomolecular condensates are physiologically relevant? Check out our latest, out today in Cell @CellCellpress , in which we identify WNK kinases as physiological crowding sensors that regulate cell volume via phase separation 1/
cell.com/cell/fulltext/S0092…
New commentary on @Kidney_Int highlighting the strengths and limitations of our new study with emerging insights on the complex regulation of NCC in the DCT. "Chloride-sensitive signaling turns the potassium switch on" kidney-international.org/art…
Adrian Murillo-De-Ozores retweeted
Multiple molecular mechanisms are involved in the activation of the kidney NaCl cotransporter by #hypokalemia
doi.org/10.1016/j.kint.2022.…
@armurillo64 @hectorcarbajalc @gerardo_gamba
Adrian Murillo-De-Ozores retweeted
De acuerdo con estimaciones de múltiples países hechas por Lancet (sept 14, 2022), México pagó a la pandemia COVID el mayor tributo en vidas humanas.
Si eso no nos convence de que necesitamos invertir más en salud, nunca, nada, nos va a convencer.
Adrian Murillo-De-Ozores retweeted
Very proud of our newest paper! This work shows the discovery of redundant and complex, novel mechanisms that regulate low K+ activation of sodium reabsorption. Feel free to discuss about our findings and their implications in health and disease. Congrats everyone!
Happy to share my new paper, discussing molecular mechanisms involved in WNK4-SPAK-NCC activation by low K intake. Special thanks to @hectorcarbajalc and my mentors @gerardo_gamba and Maria Castañeda @Kidney_Int. kidney-international.org/art…
Happy to share my new paper, discussing molecular mechanisms involved in WNK4-SPAK-NCC activation by low K intake. Special thanks to @hectorcarbajalc and my mentors @gerardo_gamba and Maria Castañeda @Kidney_Int. kidney-international.org/art…
Adrian Murillo-De-Ozores retweeted
Salt substitute really worked well to reduce major cardiovascular events in a large randomized trial conducted in China
@NEJM today #ESCCongress2021
nejm.org/doi/full/10.1056/NE…
