Inmunologist. Opinions my own.
Joined February 2020
- Tweets937
- Following950
- Followers294
- Likes6.4K
Alice Grey retweeted
Rituximab refractory or intolerant immune TTP cases are very difficult to manage. Paper in @BrJHaem from France suggest that Daratumumab is a reasonable therapeutic option. tinyurl.com/59p7ybwt #TTP #daratumumab
Alice Grey retweeted
A woman with aggressive refractory systemic lupus erythematosus was treated with a short course of the bispecific antibody teclistamab (anti–B-cell maturation antigen and anti-CD3) and had a drug-free complete remission. Full correspondence: nej.md/3Th6ewX
ALT The ratios of protein to creatinine (with protein measured in milligrams and creatinine measured in grams) in the urine and blood levels of hemoglobin in relation to the patient’s medication history during the 12 months before the start of teclistamab treatment and in relation to the tapering of glucocorticoid doses after the completion of teclistamab treatment.
Alice Grey retweeted
Thank you for your inspiring visit to MCRI @alex_fsantos!
Our @NACEresearch, @CRE_CFAR and @MCRI_for_kids Allergy Flagship early-mid career researchers gained so much from your insights.
#Allergy #AllergyResearch #ASCIA2024
#ASCIA2024 | Ahead of the @ascia_news Conference this week, international speaker and #foodallergy expert, Professor @alex_fsantos visited @MCRI_for_kids.
Thank you for your insightful seminar: Transforming Food Allergy Care Through Translational Immunology Insights.
Alice Grey retweeted
Congratulations to the authors 4 finally putting this decade-long ❓ to rest.
@NatureMedicine
We can all sleep better (or worse 😬) tonight, knowing CH causes atherosclerosis & not the other way around.
That’s some pretty “determinate” potential, I’d say 😉
TET2> DNMT3A & of course ⬆️ VAF >⬇️ VAF💡
nature.com/articles/s41591-0…
#hemepath #leusm
Alice Grey retweeted
NLRP3 inflammasome activation in circulating myeloid cells by human RAC2 GOF variants linked to rare immune disorders @JExpMed @lauboye
doi.org/10.1084/jem.20231562
Alice Grey retweeted
1/ Exactly one year after my PhD defense, I am very excited to share with you the last chapter of my thesis published today in @Nature about humans with inherited TNF deficiency: nature.com/articles/s41586-0….
Alice Grey retweeted
Neffy epinephrine nasal spray was approved by the FDA today. This provides the first epinephrine product for treatment of anaphylaxis that does not require an injection. Read the FDA announcement tinyurl.com/3fj2kvra
Long-Term Effectiveness and Discontinuation of Dupilumab in Patients With Atopic Dermatitis jamanetwork.com/journals/jam…
Alice Grey retweeted
Efficient detection of somatic UBA1 variants and clinical scoring system predicting patients with variants in #VEXAS syndrome academic.oup.com/rheumatolog…
Alice Grey retweeted
Read a review of allergic manifestations of inborn errors of immunity. It highlights patterns of allergic disease linked to disturbances of specific molecular pathways and provides examples of precision treatments that target these TH2-driven processes. bit.ly/3LVN0c0
Alice Grey retweeted
The 10 biggest medical research papers from this week (in my opinion!)
1. The mTOR inhibitor, Rapamycin, extends lifespan in healthy mice, as does the MEK inhibitor, Trametinib
Combining both together boosts mice lifespan by ∼30%
biorxiv.org/content/10.1101/…
🧵
Alice Grey retweeted
#Allergenic potency of various #foods of mammalian origin in patients with #α-Gal syndrome: even processed mammalian #meat constitutes a risk and #dairy products show the lowest risk.
ivancevichmd.blogspot.com/20…
Alice Grey retweeted
Two kids with HSV-1 encephalitis were found by @casanova_lab to have rare mutations that indirectly allowed the virus to enter their brain cells, demonstrating how protein deficiencies and mutations can facilitate brain inflammation via viral infection. nature.com/articles/s41586-0…
Alice Grey retweeted
Systematic review for Rx of calcinosis. Remains a major challenge in patients with #SSc.Several💊 have been tried with variable results.None have regulatory approval.Small studies,no validated outcome mesures & needs prolonged obvservation #Rheumatology #MedTwitter(L.Chang et al)
Alice Grey retweeted
Check our latest paper on immunomodulatory treatments for IgE-mediated food allergy - an important and independent systematic review of the literature and metanalysis to inform the new upcoming clinical guidelines from EAACI @EAACI_HQ @EAACI_JM @KingsCollegeLon @EvelinaLondon
Open Access: Immunotherapy and biologics in the management of IgE-mediated food allergy: Systematic review and meta-analyses of efficacy and safety. First author: Carmen Riggioni; corresponding author: Alexandra F. Santos
Read the article here: doi.org/10.1111/all.16129
To support future EAACI Guidelines on the treatment of IgE-mediated food allergy using #biologics or #immunotherapy, Riggioni et al. conduct a systematic review and meta-analysis including 121 new studies of randomized-controlled trials or quasi-controlled trials (8 tables and 9 figures).
#Allergy_journal @alex_fsantos
Read more articles published in #Allergy on #foodallergy here: journalallergy.com/Food-Alle…
Alice Grey retweeted
In selected patients with refractory high risk myasthenia gravis, cyclophosphamide resulted in rapid remission induction, corticosteroid reduction & long-term freedom from recurrent injectable therapy- check it out @JNNP_BMJ @syd_health jnnp.bmj.com/content/early/2…
Alice Grey retweeted
For people with fire ant allergy, stings may cause a life-threatening reaction called anaphylaxis. Symptoms may include itching and hives, swelling in the throat or tongue, difficulty breathing, dizziness, stomach cramps, nausea or diarrhea. #FireAnts
ow.ly/iNfi50SmNo1
Alice Grey retweeted
#EULAR2024
New EULAR recommendations for managing systemic sclerosis (SSc) are here! Let's break down the key points for effective patient care. 🧵
RP: CCB ➡️ PDE5i➡️ IV iloprost
DU: PDE5i/ IV iloprost
DU Prevention : Bosentan
Alice Grey retweeted
#Pregnancy is of course one of the important aspect in #lupus 🦋🤰🦋
👉Obstetric complications
👉importance of international collaboration evidence
👉🔑drug HCQ‼︎‼︎
Overall wonderful talk🥹❤️👏
Recommend watching via YouTube📺
#EULAR2024
アツイ~🔥!!
