We are pleased to announce that registration for ISHEN2025 is now open!
ishen.org/ishen-2025/registr…
We are accepting late breaking abstracts
ishen.org/ishen-2025/abstrac…
NOTE: There is very limited space. Registration will be open until full capacity
👉 Register today!
CLabenz retweeted
🚨 #GIHepFellowshipBootcamp is heating up with these 🔥 📑s on #HepaticEncephalopathy 🧠
⭐️ Testing for CHE‼️
⭐️ Risk factors for OHE‼️
⭐️ Preventing OHE‼️
⭐️ ⭐️ Treating HE ‼️ 💊 💩
journals.lww.com/hepcomm/ful…
journals.lww.com/hepcomm/ful…
CLabenz retweeted
📄 Full paper: journal-of-hepatology.eu/act…
📚 Related paper challenging the 24h albumin new rule: pubmed.ncbi.nlm.nih.gov/4025…
#EASL2025
CLabenz retweeted
💉 Albumin duration & AKI response in cirrhosis
Eva M. Schleicher (Mainz) – #EASL2025
🕒 24h albumin new rule questioned
🏆 EASL AKI response definition wins
📈 20% of 24h NR improved at 48h
⚖️ Early vs late responders: Same mortality
🚨 Cr ↑ >16% @24h → terlipressin!
👇
CLabenz retweeted
Today’s #readoftheweek📚discusses QuickStroop, which is a rapid screening tool to identify patients at risk for PHES-MHE, especially in patients below 60 years of age.
Read here this @JHEP_Reports article: jhep-reports.eu/article/S258…
🙏@c_labenz @SJGairing @kaps_leonard @EvSchleicher @Maria_M_Gabriel @HeinerWedemeyer @b_maasoumy et al.
#LiverTwitter #LiverX
CLabenz retweeted
❗QuickStroop for screening for minimal hepatic encephalopathy in patients with #cirrhosis
🔓#OpenAccess at 👉jhep-reports.eu/article/S258…
#LiverTwitter
CLabenz retweeted
Non-Invasive CSPH Estimated Risk (NICER) model including @Echosens SSM by VCTE at 100Hz
👉Developed (2020-2022) & validated (2023) in contemporary pts.
👉Outperforms ANTICIPATE(-NASH): AUC consistently >0.9.
👉Well-calibrated.
👉Sets a new standard IMHO.
#LiverTwitter
🔗👇
CLabenz retweeted
Thrilled to have this work out in @HEP_Journal !
Short version:
The problem - it’s hard to diagnose minimal HE or predict future overt HE in clinic
What we found - automated speech analysis can do both
CLabenz retweeted
"No value of non-selective beta-blockers after TIPS-insertion" published 'open access' at bit.ly/3AF9rjs
#livertwitter #TIPS

ALT In this study comprising 305 patients with transjugular intrahepatic portosystemic shunt (TIPS)-insertion, treatment with non-selective beta-blockers (NSBB) after successful portal pressure reduction via TIPS was not associated with lowered risk for hepatic or cardiac decompensation and mortality. Similarly, no impact on systemic inflammation, as measured by WBC, CRP and systemic inflammatory markers (SIM), during follow-up was found.
CLabenz retweeted
WHAT'S AT STEAK IN NUTRITION FOR HEPATIC ENCEPHALOPATHY?
No one had more fun than me and @c_labenz writing this editorial: journals.lww.com/ctg/pages/a…
On @JasmohanBajaj trial of meat vs veg burgers and ammonia: journals.lww.com/ctg/fulltex…
CLabenz retweeted
Replying to @mathiasjachs
@mathiasjachs & the Non-Invasive CSPH Estimated Risk (NICER) model based on a contemporary cohort integrating SSM-100Hz 👏
👉 Developed in SLD & 🦠 suppression/cure
👉 Improved discrimination & calibration.
👉 It's just the NICER model, I guess! 😜
Thanks @BavenoCoop!
CLabenz retweeted
Brilliant State of the Art talk by @dthabut on hepatic encephalopathy 🤩
Love that HE is getting this spotlight @EASLnews
As the Professor stated: HE is the worst complication of cirrhosis
We have a lot of work to do to improve this for our patients
CLabenz retweeted
1+ 1 = 3
Lactulose + Rifaximin = Reduced episodes of hepatic encephalopathy
journals.lww.com/hepcomm/ful…
@HepCommJournal
CLabenz retweeted
There is no stepwise increase in the risk of encephalopathy with worsening psychometric scores in this international study
journals.lww.com/hepcomm/ful…
@HepCommJournal @SJGairing @BloomPringle @c_labenz
CLabenz retweeted
🔑Are all proteins🟰 for ammoniagenesis? No!
🔑Can one meal change affect ⬇️#ammonia in #cirrhosis? Yes!
✅our #RCT where 1⃣ meal change from 🥩to 🌱/🌿-based was enough to⬇️#ammonia !
🔑Impt because replacing full diets⛔️
🔑metabolomic changes
@ACG_CTG ⤵️
journals.lww.com/ctg/abstrac…
CLabenz retweeted
🟪NEW Article in press❕
Proton pump inhibitor use and risk of hepatic encephalopathy: a multicenter study
🔓#OpenAccess at 👉jhep-reports.eu/article/S258…
#LiverTwitter
#HepaticEncephalopathy
CLabenz retweeted
Are you busy with #hepatology clinical work?
Check out the clinical care points in this short and concise review on the cerebral effects of #cirrhosis and #portalhypertension from a group of @ISHENliver members.
Out now in Clinics in #LiverDisease. 👇
authors.elsevier.com/a/1i-BM…
Is PPI use associated with HE? Our multicenter study says no 🚫
✅1160 patients with PHES at baseline
🚫no association between PPI use and MHE or OHE development
🚫>70% without an indication for a PPI prescription❗️
👉read the study here: jhep-reports.eu/article/S258…
Grateful for an amazing team effort! @SJGairing @MontagneseSara @BloomPringle @MMLauridsen @jumarquardt @ISHENliver @JHEP_Reports

































