MD Phd, Cinical Scientist, Biochemist
Mainz, Deutschland
Joined April 2019
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We tested nanoparticle formulated alendronate to achieve a high drug load in liver for antifibrotic treatment:
"pH-degradable, bisphosphonate-loaded nanogels attenuate liver fibrosis by repolarization of M2-type macrophages"
pnas.org/doi/10.1073/pnas.21…
Leonard Kaps retweeted
💉 Albumin duration & AKI response in cirrhosis
Eva M. Schleicher (Mainz) – #EASL2025
🕒 24h albumin new rule questioned
🏆 EASL AKI response definition wins
📈 20% of 24h NR improved at 48h
⚖️ Early vs late responders: Same mortality
🚨 Cr ↑ >16% @24h → terlipressin!
👇
Leonard Kaps retweeted
Thanks Baveno for highlighting this important topic! ☔️🌂
💉 Albumin duration & AKI response in cirrhosis
Eva M. Schleicher (Mainz) – #EASL2025
🕒 24h albumin new rule questioned
🏆 EASL AKI response definition wins
📈 20% of 24h NR improved at 48h
⚖️ Early vs late responders: Same mortality
🚨 Cr ↑ >16% @24h → terlipressin!
👇
Leonard Kaps retweeted
Such a great group! Can’t believe it’s been 7 years! @ZGordonJiang @Drfattyliver @AjmeraVeeral @kaps_leonard @GSzaboMD
Leonard Kaps retweeted
Incorporating the use of the Clinical Frailty Scale in clinical practice can help to identify patients with cirrhosis who may be at a higher risk of developing hepatic encephalopathy. @EvSchleicher @kaps_leonard @schattenbergJ @SJGairing #GItwitter
brnw.ch/21wGWKz
Leonard Kaps retweeted
🔍 Evaluating the annual risk of #HCC based on underlying liver disease @NatRevClinOncol
Do these numbers for ALD/MASLD reflect your clinical practice? 🤔 Please vote👇
#livertwitter @juanpabloarab @ArndtVogel @BCLC_group @maximeronot @NaultJc @jnkath @ma5RN @rabataller @EASLedu
Leonard Kaps retweeted
Tesla Full Self-Driving capability demo in Austin
FSD capability features use vision neural networks to perceive & understand the world, just like humans do.
Via our unique fleet learning approach, we are able to collect anonymized data from our vehicles—meaning the neural nets have learned from a few orders of magnitude more driving scenarios than the average human driver (including unusual & weird ones!)
Leonard Kaps retweeted
Liveblog: ++ Israels Militär erwartet schwere Verluste ++ tagesschau.de/newsticker/liv… #Israel #Liveblog
Leonard Kaps retweeted
Congrats @JasmohanBajaj and team! You bring MHE testing into the real world. Time for validation in different parts of the world @MMLauridsen @ISHENliver
Leonard Kaps retweeted
Extremely proud of these two rising stars of hepatology @EvSchleicher and Henrike Dobbermann. Both won important prizes at the #DGVS congress 2023! @jumarquardt @UnimedizinMainz @UKSH_KI_HL
Leonard Kaps retweeted
Masterclass Reunion of 2017
#EASL #AASLD #liver #conference
Nice to see you again – at Vienna, Austria
Masterclass Reunion of 2017
#EASL #AASLD #liver #conference
Nice to see you again – at Vienna, Austria
Effect of hepatic steatosis and associated metabolic comorbidities on health‐related quality of life in people living with HIV aasldpubs.onlinelibrary.wile…
CAF as key target for antistromal therapy in liver cancer!
Targeting Cancer Associated Fibroblasts in Liver Fibrosis and Liver Cancer Using Nanocarriers mdpi.com/816180 via @MDPIOpenAccess
Symptom burden is significant in patients with PBC. Beside pruritus, fatigue was reported to be burdensome even though patients show an adequate biochemical response to UDCA!
link.springer.com/article/10…
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#AASLD 2019 #Nanoparticles #posterpresentation #Bundeswehr
Nice work of Niklas Choteschovsky presented by the AASLD this year. Nanoparticlur Alendronte showed an antibiotic effect in CCl4 liver fibrotic mice
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Leonard Kaps retweeted
A first of its kind public-private partnership with the Government of Ghana to improve the diagnosis and accelerate treatment for people with #sicklecell disease, including making medicine available to people diagnosed with the disease. Learn more: bit.ly/2Q2z3gV
