Epitalon 🧬, to really move the lever on rest and recovery with Tesamorelin coming aboard the research trip. Epitalon gets the nod from the ball coach Epitalon, synthetic tetrapeptide Ala-Glu-Asp-Gly (AEDG) has a potential role in biological aging with an extremely interesting mechanism relating to telomere biology and longevity Preclinical work shows that Epitalon can increase hTERT expression, promote telomerase activity, and increase telomere length in human cell models. This work shows us some benefit in longevity. Pretty damn cool eh? Epitalon research has also been utilized to investigate for its effects on: - Circadian regulation - Pineal/melatonin signaling - Oxidative stress - Cellular senescence - Neuroendocrine function The longevity angle is as intriguing as almost anything I’ve researched in the current peptide world. But what am I focusing my sights on for this research? Circadian regulation For this winter, I’m focused on the circadian regulation, oxidative stress and melatonin signaling because recovery is CRUCIAL Shorter days mean changes in our light exposure and circadian cues. My sleep also tends to be significantly worse during the winter months So I’m interested to see how much impact this little guy can have on my sleep/circadian rhythm during the darker months. And I’m excited for it, love the anecdotal reports I’ve read @RegenRandy has a lovely breakdown of this Epitalon angle that I’ll attach below. It’s pretty kick ass Looking forward to the next 3-4 months of research. We’ve got Tirz, Tesa And Epitalon involved for this rodeo. Spot doses of TA1 We’re ready to rock through the cold months Labs, observations and data to come Let’s research 🧪 Not medical advice.