The Physics of Life and Quantitative Biology Fellow at Sheffield Uni. Interdisciplinary Biophysics on Chromatin organising machines. Views are my own.
Joined January 2019
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I am very pleased to share my new preprint! We use a new assay to interrogate how human TOP2a resolves catenated DNA. Here is a thread: 1/n biorxiv.org/content/10.1101/β¦
Dr. Erin E. Cutts π©βπ¬ retweeted
π¨Weβre hiring!
Passionate about #microscopy, #biophysics and #interdisciplinaryresearch? There's still time to apply for our EPSRC PhD project on how actin network architecture shapes the mechanical properties of cells at @sheffielduni
Learn more/Apply: findaphd.com/phds/project/foβ¦
Dr. Erin E. Cutts π©βπ¬ retweeted
The study of KIF4A-mediated human condensin I activation is out! Congrats to @cutts_dr, L. Aragon, @DamlaTetiker !
Chromokinesin KIF4A activation of human condensin I involves a SLiM interfering with auto-inhibitory intramolecular interactions within condensin, exemplifying a conserved mechanism for regulating diverse SMC complexes
@cutts_dr, Luis Aragon et al
embopress.org/doi/full/10.10β¦
There is nothing like seeing an article online!
Chromokinesin KIF4A activation of human condensin I involves a SLiM interfering with auto-inhibitory intramolecular interactions within condensin, exemplifying a conserved mechanism for regulating diverse SMC complexes
@cutts_dr, Luis Aragon et al
embopress.org/doi/full/10.10β¦
Dr. Erin E. Cutts π©βπ¬ retweeted
Our work on SMC Wadjet complex is finally out @MolecularCell ! Congrats to @BisLightyear @iamamardeeep @_KevinCorbett & co.!
Online Now: Loop-extrusion-mediated plasmid DNA cleavage by the bacterial SMC Wadjet complex dlvr.it/TGXdm1
Dr. Erin E. Cutts π©βπ¬ retweeted
The short talk abstract deadline for the Keystone Interplay of Chromatin Architecture and Transcription Regulation meeting is coming up (Jan 9). The meeting is being held jointly with the Epigenetics in Development and Disease meeting, and it will be awesome! #KSChromatin25
I have two PhD positions available in my group next year! These projects are looking at how disordered regions alter protein dynamics. One is through the Yorkshire BBSRC DTP, advertisement to come, but more information can be found here: whiterose-mechanisticbiologyβ¦
Please get in touch to hear more about the application process and project. Check out my website for more information: cuttslab.uk
There are a bunch of great projects at Sheffield worth checking out as well: findaphd.com/phds/project/mrβ¦
Dr. Erin E. Cutts π©βπ¬ retweeted
βWeβre very excited to see what people do with thisβ
AlphaFold3 is open at last go.nature.com/4fHAfio
Dr. Erin E. Cutts π©βπ¬ retweeted
Excited to share that the AlphaFold 3 model code and weights are now available for academic use.
Looking forward to seeing what new research this unlocks and how the research community builds on AlphaFold 3 for scientific discoveries github.com/google-deepmind/a⦠1/2
Dr. Erin E. Cutts π©βπ¬ retweeted
A quantitative intracellular peptide binding assay reveals recognition determinants and context dependence of short linear motifs biorxiv.org/cgi/content/shor⦠#biorxiv_biochem
Dr. Erin E. Cutts π©βπ¬ retweeted
Very proud of @BoyaZhang4 and this lovely first paper, first of many I am sure.
My first author paper is now online in @OpticaWorldwide ! Please allow me introduce Vortex Light Field Microscopy: a simple and efficient way of achieving 3D spectral single-molecule imaging. Comments and feedbacks are welcome!
@CamMicroscopy @PDN_Cambridge @Cambridge_Uni
Dr. Erin E. Cutts π©βπ¬ retweeted
π₯JOB ADVERTπ₯
Looking for a postdoc to work on #machine_learning classification of #knots & #proteins and discovery of new topological invariants.
Start by November 2025
Duration 2 years min
Where: TAPLab @PhysAstroEd
Generously funded by @LeverhulmeTrust
Retweet pls β€οΈ
Dr. Erin E. Cutts π©βπ¬ retweeted
Exciting! Meeting all my colleagues working on SMC complexes in Numazo Japan: niki-lab.sakura.ne.jp/NIGIS2β¦
Dr. Erin E. Cutts π©βπ¬ retweeted
New work from the lab!
James Stowell led this project showing the importance of multivalency and phospho-regulation in mRNA decay. This has many parallels with other mechanisms in gene expression... 𧡠1/
#RNA #NMR #bioRxiv @MRC_LMB @ERC_Research
Brilliant to be in Japan at the SMC meeting presenting my work on Condensin regulation! Huge thanks to @Co_Biologists and @Official_BSCB for a travel grant to help me get here!
Dr. Erin E. Cutts π©βπ¬ retweeted
I am super excited to show our work, now published in NAR @NAR_Open, on the structural function of SLF1 at the stalled replication fork. @AstburyCentre @ScienceLeeds academic.oup.com/nar/articleβ¦
