Physician-scientist | Chief Medical Scientist, Lore : Agency + health | Advisor: Biopharma R&D + health technology | HMS DBMI | AEI
Boston
Joined October 2011
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“I've lost close family members to cancer that didn't yet have treatments available, the hardest part for them wasn't affording it.
A lack of innovation is access problem we often overlook because it isn't as salient-but it is a far larger barrier than price.” - @C_Garthwaite
@dansenor - ty for recommending @ArkMediaOrg pcast feat @SaysCL & @yaelbt -More than good: cathartic. Mandy P rant alone worth price of Ark subscription. But predominant emotions I come away from show w=combo of appreciation+joy+love - of faith, 🇺🇸, wit, & unashamed exuberance
See also: "Look at this validation - our name and photos in huge letters in Times Square on the NASDAQ screen!"
(basically startup version of Who's Who scam)
PE fund press release: “Thrilled to be named to @Inc’s Founder-Friendly Investors list!”
Also PE fund: quietly pays several thousand dollar application fee to Inc., submits their own founder references, then blasts the press release like they just won the Nobel Prize.
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David Shaywitz retweeted
You don’t have to love powerlooms or hate hand weaving to recognize a powerloom when you see one.
Lots of intellectual tasks that used to be pure craft & which, therefore, could never be industrialized might soon be subject to the logic of industrialization. Not an easy change.
David Shaywitz retweeted
Kidding aside, one aspect of statements by Dario ahead of Anthropic IPO is big expectations about new treatments create a statement “cliff” as they will be desperate to bring new medicines forward to deliver.
Side note- it’s irksome that these tech CEOs pump everything while biotech CEOs aren’t even supposed to acknowledge (eg like) posts congratulating them during the quiet period leading into pricing & have to write (and say) tortured sentences like “We believe our potential investigational product candidate may commence a potentially registration enabling study next year but there can be no assurance such a study will ever happen or that it will support registration” instead of “We plan to start a pivotal study next year”
As always, @JackScannell13 is outstanding…
Can AI truly revolutionize drug discovery when many of the diseases we're trying to treat remain poorly understood?
Today we published our technical brief on @github and an AIxBIO interview, with drug hunter the father of “Eroom’s Law” Jack Scannell @eroomslaw.
It references the recent @nature paper he co-authored: “Artificial Intelligence in Drug Discovery: “What It Is, Where We Stand and the Path Forward.”
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David Shaywitz retweeted
Overheard at board meeting today - why is our employee health insurance cost going up 20% for next year but on our revenue side, the same insurers are cutting our rates?
For those trying to understand philosophy/approach of AI-first medical startup Counsel Heath, just acquired by Oura, highly recommend this @fittinsider interview w CEO podcasts.apple.com/us/podcas…, which I discussed here: timmermanreport.com/2026/02/…
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David Shaywitz retweeted
Best habit I picked up building agents is retrying the stuff that failed a few months ago
The no list keeps shrinking
Last 2c re: excellent @EricTopol/@emollick AI chat.
Appreciate why some so bullish on AI in life sci; as tech keeps outperforming expectations, you keep pushing it, & asking why not this?
Yet my optimism tempered by respect for complexity of human bio. timmermanreport.com/2026/08/…
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One other critical point from excellent @emollick/@EricTopol interview, perhaps THE critical point I always find myself taking away from Ethan: if you've not checked in w AI recently, you're priors are likely incredibly outdated; seems true across so many domains.
@zakkohane
Also strongly agree w @emollick’s summation to @EricTopol, “We’re all making this up as we go along.”
In fact I emphasized this exact point in latest @timmermanreport column… timmermanreport.com/2026/11/…
Also strongly agree w @emollick’s summation to @EricTopol, “We’re all making this up as we go along.”
In fact I emphasized this exact point in latest @timmermanreport column… timmermanreport.com/2026/11/…
“I see turbulence.” - @EricTopol on the future of AI; perfect distillation.
Also appreciated @EricTopol distinguishing, in chat w @emollick, between “empathy” in response to pt actors (initial data suggesting AI more empathic than mds) and in response to actual patients (the doctors did better than AI, as @AdamRodmanMD I believe has noted)
@zakkohane
Also appreciated @EricTopol distinguishing, in chat w @emollick, between “empathy” in response to pt actors (initial data suggesting AI more empathic than mds) and in response to actual patients (the doctors did better than AI, as @AdamRodmanMD I believe has noted)
@zakkohane
Great discussion! Can’t do much better than this @emollick interview w @EricTopol to get up to speed on AI in general, and potential implications for life sciences, healthcare in particular.
Also: appreciate that Ethan talks as fast and as intensely as my kids say I do….
Great discussion! Can’t do much better than this @emollick interview w @EricTopol to get up to speed on AI in general, and potential implications for life sciences, healthcare in particular.
Also: appreciate that Ethan talks as fast and as intensely as my kids say I do….
It's hard to beat @emollick for an up-to-date, independent assessment of AI, no less where we're headed. His new book is CO-EXISTENCE. We discussed that and a lot more in the new Ground Truths today
Something’s def in SF air…
1. On IPO roadshow, Anthropic ceo anticipates AI-mediated cures for AD, cancer, etc in next 10y
2. VC a16z (an investor) described Counsel Health acquisition by Oura as -> “high-quality, abundant, personalized, & proactive pt care”
@matthewherper
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I’ve discussed issues w wearables in @timmermanreport timmermanreport.com/2026/06/… & @wsj wsj.com/opinion/when-ai-tell…, and described counsel’s dehumanized-by-design vision of AI-mediated primary care in TR: timmermanreport.com/2026/02/…
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In short, Oura acquisition of Counsel strikes me, sadly, as another win for
algorithm-driven decomposition of health & for worshipping at alter of numeric optimization, another setback for relational health & care concerned w understanding & aligning w individual’s values
Vision of @CounselHealth, as I wrote for @timmermanreport in Feb...
Presumably in acquiring Counsel, @ouraring mgmt also evidently believes that future of medicine belongs to the machines....
(I had thoughts in recent @WSJ op-ed, just before IPO pulled wsj.com/opinion/when-ai-tell…)
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Vision of @CounselHealth, as I wrote for @timmermanreport in Feb...
Presumably in acquiring Counsel, @ouraring mgmt also evidently believes that future of medicine belongs to the machines....
(I had thoughts in recent @WSJ op-ed, just before IPO pulled wsj.com/opinion/when-ai-tell…)
I discussed @CounselHealth in Feb, as offering AI-driven future of primary care @LisaRosenbaum17 @NEJM fears (CEO says tech > human brain for primary care): timmermanreport.com/2026/02/… .
Well, bad news for Lisa's vision, good news for Counsel: just acquired by @ouraring for $625M.