Scientist and educator
California
Joined August 2008
- Tweets276
- Following155
- Followers155
- Likes205
Elliot Hui retweeted
New data presented today at #AHA23 show that a single administration of our #PCSK9 epigenetic editor therapeutic durably lowered cholesterol levels in vivo.
Read more: chromamedicine.com/2023/11/1…
#EpigeneticEditing #Biotech
This turned out beautifully! Congrats, @RonZhu2015 @P32jm and the rest of the team.
Two decades ago @AvigdorEldar & @BarkaiLab introduced concept of shuttling, in which protein circuits push morphogens away from their source, or smush them into narrower regions. We have now reconstituted shuttling in mammalian cell culture: science.org/doi/10.1126/scia….
Whaaaat is this!?!?!! 🤑 No more grant writing!
A minuscule handbag measuring just 657 by 222 by 700 microns (or less than 0.03 inches wide) sold for over $63,000 at an online auction cnn.it/43lHwxP
Very proud of @SeeAvash and our work on programmable pneumatic computers. Published today and featured in New Scientist. newscientist.com/article/237…
science.org/doi/10.1126/scia…
xitter.cf/SeeAvash/status/148841…
Elliot Hui retweeted
Thrilled to be presenting groundbreaking data today at #ASGCT23 demonstrating the power of harnessing an endogenous system to regulate gene expression. Check out this thread to learn how we did it. 🧵
1/7
#EpigeneticEditing #Tweetorial
Elliot Hui retweeted
I’m delighted that our paper on the Multicellularity Long Term Evolution Experiment (MuLTEE) has, at long last, been published. This paper establishes the foundations of what I’d like to work on for the rest of my career. 1/25
Free, full access link: rdcu.be/dbPA9
Elliot Hui retweeted
01. Today we report the computational design of highly efficient enzymes. Lab testing confirms that these novel luciferases can recognize specific synthetic substrates and efficiently catalyze the emission of light.
nature.com/articles/s41586-0…
Elliot Hui retweeted
🖭🖭 A Brief History of Parafilm 🖭🖭
"Cling wrap on steroids." "Duct tape of science." "The forbidden lab cheese." Parafilm has many names.
But what is this stuff? Where did it come from? And can you actually eat it? 🧵
cell.substack.com/p/parafilm
Thank you! Have been looking for something like this for a while.
Introducing the Spinout Playbook, a free guide to spinning a startup out of academia.
fiftyyears.com/spinout
Why is this needed? The process of “spinning out” science from universities is broken 👇🧵
Elliot Hui retweeted
This piece of news was worth waiting for! Ronke's @OlabisiLab 2022 @BMESociety Diversity Lecture is finally up: youtube.com/watch?v=Kfl4BTae…
Very comprehensive and highly informative!
Olabisi Presents 2022 Biomedical Engineering Society Diversity Lecture engineering.uci.edu/news/202…
Elliot Hui retweeted
After a year of building in stealth, I’m really excited today to announce the launch of Eigen Therapeutics! At @EigenTx, we develop “priming therapies” that modulate target expression levels on cancer cells, making them easier to find and eliminate.
endpts.com/priming-therapy-b…
Elliot Hui retweeted
Kamran Ali and Transon Nguyen, former UCI BME (@elliothui lab) students, started Eigen Therapeutics & just raised a $7 million seed round
Eigen's developing a highthroughput platform to discover priming therapies. This should enhance existing targeted therapies for cancers.
Targeted therapies are incredibly effective in some instances but can fail in others because cancer is heterogeneous. So we asked ourselves: what if we made cancer cells easier for targeted therapies to eliminate?
businesswire.com/news/home/2…
Elliot Hui retweeted
***See your cells without a microscope*** 👀
Introducing #UnclearingMicroscopy, where cells are expanded 8,000 volumetrically and opaqued with light-scattering molecules of high density to reveal cell microstructure with the naked eye
bioRxiv: biorxiv.org/content/10.1101/…
Elliot Hui retweeted
Tenure Track position for someone broadly focused on stem cells and tissue engineering to join strong collaborative environment at UC Irvine. Applications due by Jan 6th 2023. #tenturetrack #stemcell #UCI #facultyjob recruit.ap.uci.edu/JPF07925
ALT Aerial photograph of the UC Irvine main campus showing central Aldrich park surround by a ring of research and instructional buildings with mountains and the ocean in the background.
Elliot Hui retweeted
Our latest research has just been published today in the journal Nature. We engineered yeast to produce the cancer therapeutic vinblastine. You can find the work here: nature.com/articles/s41586-0…. It is the longest biosynthetic pathway ever refactored into yeast.
Counterfeit Aquapel? Don’t let this happen to your microfluidics! aquapel-glass-treatment.eu/a…
Truly fascinating work exploring the limits of biology in terms of temperature and time.
1/n: How slowly can life progress? It’s obvious that cells cannot duplicate in a nanosecond. But is there a limit to how slowly cell's life can progress without stopping? We answered this for budding yeast by decreasing temperature [movie of yeast at 1 C]: biorxiv.org/content/10.1101/…
Elliot Hui retweeted
Delighted to announce the publication of our work on *Microfluidic Chain Reaction* (MCR) in @Nature.
MCR help realize a true lab-on-a-chip and could perform medical tests. You may download, modify, and 3D print your own MCR chip 😎
rdcu.be/cNP7l
1/n
Elliot Hui retweeted
A bispecific #antibody which distinguishes #cancer cells from healthy cells, doesn't care about #KRAS mutations & was developed entirely on human cancer #organoids. In 3 years from drawing board to clinic. Congrats to all collaborators. Read: rdcu.be/cL4xS
