Scientist and educator

California
Joined August 2008
New data presented today at #AHA23 show that a single administration of our #PCSK9 epigenetic editor therapeutic durably lowered cholesterol levels in vivo. Read more: chromamedicine.com/2023/11/1… #EpigeneticEditing #Biotech
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Thrilled to be presenting groundbreaking data today at #ASGCT23 demonstrating the power of harnessing an endogenous system to regulate gene expression. Check out this thread to learn how we did it. 🧵 1/7 #EpigeneticEditing #Tweetorial
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I’m delighted that our paper on the Multicellularity Long Term Evolution Experiment (MuLTEE) has, at long last, been published. This paper establishes the foundations of what I’d like to work on for the rest of my career. 1/25 Free, full access link: rdcu.be/dbPA9
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01. Today we report the computational design of highly efficient enzymes. Lab testing confirms that these novel luciferases can recognize specific synthetic substrates and efficiently catalyze the emission of light. nature.com/articles/s41586-0…
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🖭🖭 A Brief History of Parafilm 🖭🖭 "Cling wrap on steroids." "Duct tape of science." "The forbidden lab cheese." Parafilm has many names. But what is this stuff? Where did it come from? And can you actually eat it? 🧵 cell.substack.com/p/parafilm
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This piece of news was worth waiting for! Ronke's @OlabisiLab 2022 @BMESociety Diversity Lecture is finally up: youtube.com/watch?v=Kfl4BTae… Very comprehensive and highly informative! Olabisi Presents 2022 Biomedical Engineering Society Diversity Lecture engineering.uci.edu/news/202…
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After a year of building in stealth, I’m really excited today to announce the launch of Eigen Therapeutics! At @EigenTx, we develop “priming therapies” that modulate target expression levels on cancer cells, making them easier to find and eliminate. endpts.com/priming-therapy-b…
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Elliot Hui retweeted
Kamran Ali and Transon Nguyen, former UCI BME (@elliothui lab) students, started Eigen Therapeutics & just raised a $7 million seed round Eigen's developing a highthroughput platform to discover priming therapies. This should enhance existing targeted therapies for cancers.
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Elliot Hui retweeted
***See your cells without a microscope*** 👀 Introducing #UnclearingMicroscopy, where cells are expanded 8,000 volumetrically and opaqued with light-scattering molecules of high density to reveal cell microstructure with the naked eye bioRxiv: biorxiv.org/content/10.1101/…
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Tenure Track position for someone broadly focused on stem cells and tissue engineering to join strong collaborative environment at UC Irvine. Applications due by Jan 6th 2023. #tenturetrack #stemcell #UCI #facultyjob recruit.ap.uci.edu/JPF07925
Our latest research has just been published today in the journal Nature. We engineered yeast to produce the cancer therapeutic vinblastine. You can find the work here: nature.com/articles/s41586-0…. It is the longest biosynthetic pathway ever refactored into yeast.
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Delighted to announce the publication of our work on *Microfluidic Chain Reaction* (MCR) in @Nature. MCR help realize a true lab-on-a-chip and could perform medical tests. You may download, modify, and 3D print your own MCR chip 😎 rdcu.be/cNP7l 1/n
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A bispecific #antibody which distinguishes #cancer cells from healthy cells, doesn't care about #KRAS mutations & was developed entirely on human cancer #organoids. In 3 years from drawing board to clinic. Congrats to all collaborators. Read: rdcu.be/cL4xS
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I am truly humbled and honored for this recognition @NatureBiotech. Thank you so much!
We continue to highlight outstanding researchers in the US to celebrate #BlackHistoryMonth. Today we recognize UC Irvine's Quinton Smith @telomerase2, whose lab is focused on bridging the gap between fundamental stem cell biology and clinical application of stem cell derivatives
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Our first work on cell-based DNA-encoded library screening is out! We're hunting for new ways to find antibacterials. Big congrats to Wesley Cochrane and Patrick Fitzgerald. pubs.acs.org/doi/10.1021/acs…
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Today we publish a paper in @ScienceMagazine that expands nanopore readings to the proteome: a nanopore-based scanner to read off PROTEINS at the single-molecule level! 🤩 Awesome experiments by postdoc Henry Brinkerhoff of our #CDlab, with MD simulations of @aksimentievLab 1/x
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Replying to @jmil
@jmil's 3D printing company @VolumetricBio has been acquired in a deal that could be worth as much as $400 million. 🔥🔥🔥 We just got one huge step closer to the reality of 3D printed organs, folks. YES!!! news.rice.edu/news/2021/rice…
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Elliot Hui retweeted
Excited to share that we have more positions open at @Merck #ProteinEngineering. We are hiring for #MolecularBiology, #Biochemistry, & #Microfluidics Join our bioengineering revolution! #SynBio #ProteinDesign #DirectedEvolution Three links👇
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Why I refer to the cell as a "bag of RNA" in my @sciencedirect article: loom.ly/tXlvMF8 #cellbiology #mRNA
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Come join the vibrant chemical biology community ⁦@UCIrvine⁩! ⁦@SpitaleLab⁩ ⁦@rachelwmartin⁩ ⁦@chang_c_liu⁩ ⁦@BrianDNA⁩ ⁦@NowickGroup ⁩⁦@TheBessLab ⁩⁦⁦@gregoryaweiss⁩ ⁦@XiaoyuShi2⁩ and several more! recruit.ap.uci.edu/JPF06994
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