Neuroscientist and Instructor at @Brain_Circuits, @BWHNeurology & @HarvardMed interested in brain networks, epilepsy, and neuromodulation. 🇳🇱in🇺🇸
Boston, MA
Joined June 2018
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Is generalized epilepsy a seizure of the whole brain or a specific brain network?
In our new paper out now in @NatureComms we investigate this by combining brain abnormalities and DBS with the human connectome.
Paper: nature.com/articles/s41467-0…
A 🧵 below:
Frederic Schaper retweeted
A recent paper in @NatureNeuro raised concerns about the lesion network mapping method. Our team of 16 coauthors analyzed >1000 lesions and 34 symptoms and found that "The methodological foundations of lesion network mapping remain sound" biorxiv.org/content/10.64898…
Frederic Schaper retweeted
Are connectome-based network mapping methods and the >200 papers that have used it invalid?
New paper out in @NatureNeuro says YES. nature.com/articles/s41593-0…
I have concerns about this new paper's methods and conclusions, but am biased. What do others think?
Frederic Schaper retweeted
Honored to highlight our work @Brain_Circuits @MassGenBrigham Neuro Research Day. Thank you @shansiddiqi @fredschaper_ Sheena Baratano and Sam Snider for sharing your experience.
Frederic Schaper retweeted
Welcome to the new term at the AAN!
Super excited to share my 1st @AANmember #PresidentSpotlight message with you! 💚 We really are minds on a mission. I found in the Academy my community — and together, as neurologists, we are stronger. Let’s get to work! 🙌✅ #NeurologyProud
25 years ago, @NataliaRostMD attended her first #AANAM as a medical student. Today, she leads the Academy as its president.
Discover more about her journey and plans for her term in this President's Spotlight Video. hubs.la/Q03lvlkR0
Frederic Schaper retweeted
An 𝐚𝐧𝐚𝐭𝐨𝐦𝐢𝐜𝐚𝐥 𝐜𝐨𝐧𝐧𝐞𝐜𝐭𝐢𝐯𝐢𝐭𝐲 𝐦𝐚𝐩 is a map of reconstructed white-matter pathways in the human brain based on diffusion-weighted MRI sequences.
To learn more about this NEJM Illustrated Glossary term, read the 2018 Review Article “Mapping Symptoms to Brain Networks with the Human Connectome”: nej.md/2FYkgAc
Explore more terms: nej.md/glossary
#Neurology
ALT Visual representation of an anatomical connectivity map
Frederic Schaper retweeted
Unexpected opening for Epilepsy/CNP fellowship this July for neurologists at @MGHNeurology @harvardmed. Open to international neurologists with ECFMG certification too. Reach out for more info #NeuroTwitter #MedEd @NMatch2025
Frederic Schaper retweeted
In a new study, researchers from @BWHNeurology and colleagues found a generalized epilepsy network derived from brain abnormalities and DBS. The study was published in @NatureComms.
Read more: bwhclinicalandresearchnews.o… doi.org/10.1038/s41467-025-5…
Frederic Schaper retweeted
Lesions causing epilepsy map to a brain circuit, but what about generalized epilepsy? Great new paper (and thread) by @fredschaper_ @Brain_Circuits identifies this circuit with implications for #DBS.
Is generalized epilepsy a seizure of the whole brain or a specific brain network?
In our new paper out now in @NatureComms we investigate this by combining brain abnormalities and DBS with the human connectome.
Paper: nature.com/articles/s41467-0…
A 🧵 below:
Frederic Schaper retweeted
A landmark paper on generalized epilepsy and CM DBS providing even more confirmation of the role of “network specific” neuromodulation for #epilepsy! Congratulations to @fredschaper_ on leading this effort!
Is generalized epilepsy a seizure of the whole brain or a specific brain network?
In our new paper out now in @NatureComms we investigate this by combining brain abnormalities and DBS with the human connectome.
Paper: nature.com/articles/s41467-0…
A 🧵 below:
We saw an interleaved pattern over the motor cortex, which reminded us of @ndosenbach 's inter-effector regions and somatocognitive action network (SCAN). Could the IGE network share connections with the SCAN?
Paper: nature.com/articles/s41586-0…
Huge thank you to @GongJunJI1 for leading this study, to @foxmdphd for his invaluable mentorship at @Brain_Circuits, and all collaborators for their support and generous sharing of data:
