infectious disease epidemiologist
Joined May 2011
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Our recent work examining the impact of #PEPFAR on the global #TB epidemic - published today in @NEJM
nejm.org/doi/full/10.1056/NE…
Jonathan Smith retweeted
Tuberculosis remains a leading cause of death worldwide among persons with HIV. In this report, the effect of the PEPFAR program on incident cases of tuberculosis and related deaths is presented. Read the full report: nejm.org/doi/full/10.1056/NE…
@CDCgov | #WorldTBDay
ALT A figure showing tuberculosis cases averted by PEPFAR (2003–2024).
Lab-confirmed #TB diagnoses in young kids often require invasive procedures that cause severe physical and mental distress. In @PLOSDigiHealth we show #MachineLearning can help clinicians decide if these costly, invasive procedures should be ordered #EndTB doi.org/10.1371/journal.pdig…
In this @CDCMMWR, we demonstrate a collection of interventions improved #MDR #TB treatment retention among highly mobile migrant patients during the #COVID19 in India. It will take a lot of hard work, but #YesWeCanEndTB #WorldTBDay #EndTB cdc.gov/mmwr/volumes/72/wr/m…
Jonathan Smith retweeted
Thank you Dean Fallin of @EmoryRollins and Dr. Lash of @EmoryEPI for stopping by to support the TRAC before World TB Day @DeanDaniFallin @neelrgandhi
Our study on isolation and quarantine behaviors in the US during the #COVID19 pandemic found that most infected individuals chose to isolate. Contact tracing helped, but the proportion of adults engaging with the public health system was suboptimal academic.oup.com/cid/advance…
Congrats to @kennyguna and team for spearheading important work in guiding sensible and clinically appropriate decision making in pediatric #TB - one of the leading causes of death for children worldwide. An enormous step forward to #EndTB thelancet.com/journals/lanch…
We used whole genome sequencing from a population-based cohort and 2 decades of clinical encounter data to identify nosocomial transmission of #tuberculosis in Botswana: odds were over 6x in rural vs urban facilities. Read more @AmJEpi #EndTB #StopTB #TB academic.oup.com/aje/advance…
Jonathan Smith retweeted
In a recent study, scientists searched for population-based analysis in which #WGS was used to estimate #TB transmission and clusters. Identifying geographic sources may have a considerable impact on controlling and mitigating TB transmission.
bit.ly/3Bkg606
Jonathan Smith retweeted
New in @AmJEpi - @jpsmithuga @ted_h_cohen @davidwdowdy @soustha @neelrgandhi and Hill offer a systematic analysis quantifying tuberculosis transmission dynamics from 8 global settings @societyforepi. Check it out here ➡️ doi.org/10.1093/aje/kwac181
Jonathan Smith retweeted
Clinical and radiologic factors associated with detection of Mycobacterium tuberculosis in children under 5 years old using invasive and noninvasive sample collection techniques - Kenya
✅ Just Accepted
🔓 Open Access
🔗 bit.ly/3TA70mT
Diagnosing kids with #TB is among the greatest ongoing challenges to #EndTB - 96% of kids who die of TB are undiagnosed. Here, we examine clinical/CXR factors associated w/ lab-confirmed TB in young kids across multiple sample techniques @OFIDJournal #tb academic.oup.com/ofid/advanc…
Jonathan Smith retweeted
New in AJE:
Interested in #TB transmission dynamics? This systematic analysis of whole genome sequencing data estimates that 80% of TB transmission occurs from less than 30% of cases
@jpsmithuga @neelrgandhi @ted_h_cohen @soustha @davidwdowdy
doi.org/10.1093/aje/kwac181
Interested in #TB transmission dynamics? Our new systematic analysis quantifying #TB transmission is out in @AmJEpi - we found most TB is spread by a minority of cases across global settings @davidwdowdy @neelrgandhi @ted_h_cohen @soustha @Emory_TB_Center academic.oup.com/aje/advance…
Jonathan Smith retweeted
New systematic analysis in @AmJEpi using whole genome sequencing to identify #TB transmission clusters suggests 2-31% of cases drive >80% of TB transmission across global settings. @jpsmithuga @ted_h_cohen @soustha @davidwdowdy @neelrgandhi academic.oup.com/aje/advance…”
Understanding TB transmission dynamics in high-burden settings is notoriously challenging. Here we use geospatial, genotypic, & clinical data of #TB cases in Botswana and find transmission dynamics vary markedly between high-burden subpopulations #endTB nature.com/articles/s41598-0…
Jonathan Smith retweeted
A recent CDC study of tuberculosis (TB) transmission in Botswana shows little risk from healthcare settings and highlights the need for targeted interventions aimed at community spread of #TB. Learn more about the findings: bit.ly/3v7O7fV
Healthcare facilities are high-risk for TB transmission, but how do they contribute to the overall TB epidemic? We combined detailed cohort and 2 decades of clinical encounter data to find ~5% of all TB transmission is attributed to HCFs in Botswana @iche bit.ly/3JFixeG
Jonathan Smith retweeted
Model-based analysis of tuberculosis genotype clusters in the United States reveals high degree of heterogeneity in transmission, and state-level differences across California, Florida, New York, and Texas academic.oup.com/cid/advance…
Some people spread TB more than others. In the March issue of @EpidemiologyLWW, we evaluate a method to quantify these individual differences despite not knowing who infected whom, allowing us to better assess the propensity for a large outbreak. journals.lww.com/epidem/Abst…
