@lollo_pasquini

Computational and clinical neuroscientist. Interests include: fMRI, autonomic physiology, emotions, aging, and psychedelics.

 San Francisco, USA
neuroscape.ucsf.edu/profile/lorenzo-pasquini/
Joined August 2020
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Intrinsic brain activity gradients dynamically coordinate functional connectivity states disq.us/t/3r0ewvo
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Listening to "Health Benefits of Psychedelic Retreats for Older Adults, Expert Insights with Dr. Lorenzo Pasquini & Hannes Kettner" at buzzsprout.com/265442/episod…

Health Benefits of Psychedelic Retreats for Older Adults, Expert...

In this episode of Causes or Cures, Dr. Eeks chats with Dr. Lorenzo Pasquini and Hannes Kettner about their research on the effects of psychedelics in older adults who attended psychedelic retreats!...

buzzsprout.com
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Check out our new preprint, assessing changes in dynamic and effective connectivity of frontostriatal circuits following #psilocybin administration in healthy, psychedelic naive volunteers: biorxiv.org/content/10.1101/… Many thanks to @VohryzekJakub , @GustavoDeco and @RCarhartHarris

Long-term effects of psilocybin on dynamic and effectivity connectivity of fronto-striatal-thalamic...

Psilocybin has been shown to induce fast and sustained improvements in mental well-being across various populations, yet its long-term mechanisms of action are not fully understood. Initial evidence...

biorxiv.org
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Lorenzo Pasquini, PhD retweeted
Brain@Brain18788 Sep 2024
Evolutionary perspectives on mRNA signatures of neurodegeneration-related brain remodelling New scientific commentary by Ting Shen & Corey McMillan tinyurl.com/ynvd3nn8
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Our new paper exploring the link between atrophy in #FTD, recently evolved genes, and cryptically spliced genes is finally out in @Brain1878! academic.oup.com/brain/advan… Many thanks to co-authors at @UCSFmac, in particular @flpsw, @brucemillerucsf, @AditFriedberg, and Bill Seeley

Frontotemporal lobar degeneration targets brain regions linked to expression of recently evolved...

Frontotemporal lobar degeneration (FTLD) erodes brain functions that have evolved relatively recently in humans, such as language and social behaviour. Pas

academic.oup.com
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Lorenzo Pasquini, PhD retweeted
Julio Leon@SCIJulioLeon2 Jul 2024
1/ I am happy to share that our latest research paper is now available as a preprint on bioRxiv! 🧠🧬Integrative Transcriptomics Reveals Layer 1 Astrocytes Altered in Schizophrenia biorxiv.org/content/10.1101/…
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Check our new paper "Effects of Psychedelics in Older Adults: A Prospective Cohort Study". Congrats to @KettnerHannes for pushing this through! sciencedirect.com/science/ar…
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Check our new preprint exploring longitudinal changes in well-being among older adults attending psychedelic group sessions, great effort by @KettnerHannes: doi.org/10.21203/rs.3.rs-397…

Improvements in well-being following naturalistic psychedelic use and underlying mechanisms of...

Affective symptoms such as anxiety, low mood, and loneliness are prevalent and highly debilitating symptoms among older adults (OA). Serotonergic psychedelics are novel experimental interventions for...

researchsquare.com
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Brain substates induced by DMT relate to sympathetic output and meaningfulness of the experience biorxiv.org/content/10.1101/…

Brain substates induced by DMT relate to sympathetic output and meaningfulness of the experience

N,N-Dimethyltryptamine (DMT) is a serotonergic psychedelic, known to rapidly induce short-lasting alterations in conscious experience, characterized by a profound and immersive sense of physical...

biorxiv.org
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Check our new preprint on brain dynamics under DMT! biorxiv.org/content/10.1101/…. DMT induces acute hippocampal and medial parietal deactivations, which correlate with meaningfulness of the experience and lower increases in heart rate.

Brain substates induced by DMT relate to sympathetic output and meaningfulness of the experience

N,N-Dimethyltryptamine (DMT) is a serotonergic psychedelic, known to rapidly induce short-lasting alterations in conscious experience, characterized by a profound and immersive sense of physical...

biorxiv.org
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Is there a link between FTLD atrophy and genes that recently evolved in humans? Check out our new preprint: medrxiv.org/content/10.1101/…

FTLD targets brain regions expressing recently evolved genes

In frontotemporal lobar degeneration (FTLD), pathological protein aggregation is associated with a decline in human-specialized social-emotional and language functions. Most disease protein aggrega...

medrxiv.org
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Lorenzo Pasquini, PhD retweeted
medRxiv@medrxivpreprint29 Oct 2023
FTLD targets brain regions expressing recently evolved genes medrxiv.org/cgi/content/shor… #medRxiv
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Lorenzo Pasquini, PhD retweeted
Robin Carhart-Harris
@RCarhartHarris11 Oct 2023
San Francisco Bay Area residents only, who are healthy, no history of psychiatric illness, good prior experience with psychedelics, prior experience being scanned with MRI, check this study:clinicaltrials.ucsf.edu/tria…. Please only reach out if you are eligible [strictly enforced].

UCSF Psychedelic Experiences Trial: Neural and Physiological Correlates of Psychedelic Sub-states

This Psychedelic Experiences and Neuroimaging study at UCSF ends January 30, 2027.

clinicaltrials.ucsf.edu
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Lorenzo Pasquini, PhD retweeted
Suzee Lee@lee_suzee17 Jul 2023
Thrilled about our new pub in Ann Neurol that examine Connectivity alterations in MAPT mutation carriers. Congrats, Liwen! @liwen_leven. Huge thanks @allftd, @jesseaaronbrown @lollo_pasquini @brainsturming @YokoyamaLabUCSF @UCSFmac! onlinelibrary.wiley.com/doi/…

Network Connectivity Alterations across the MAPT Mutation Clinical Spectrum

Objective Microtubule-associated protein tau (MAPT) mutations cause frontotemporal lobar degeneration, and novel biomarkers are urgently needed for early disease detection. We used task-free functi...

onlinelibrary.wiley.com
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Lorenzo Pasquini, PhD retweeted
Adit Friedberg@AditFriedberg26 May 2023
Interested in #creativity? New piece @sciam beautifully displays the #FTD #creativity story! Including our research @UCSFmac @GBHI_Fellows @ucsfhealth with @brucemillerucsf Bill Seeley @lollo_pasquini @RabLab_UCSF @Rankin_Lab bit.ly/FTDCreativitySciAm
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Lorenzo Pasquini, PhD retweeted
Imaging Neuroscience@ImagingNeurosci17 Apr 2023
All NeuroImage and NeuroImage:Reports editors have resigned over the high publication fee, and are starting a new non-profit journal imaging-neuroscience.org This comes with great regret, and a huge amount of thought and discussion- please read announcement to get more details.
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Lorenzo Pasquini, PhD retweeted
Lorenzo Pasquini, PhD@lollo_pasquini26 Mar 2023
I am looking to submit a Diversity Supplement to @NIHAging to hire a coordinator to work on cognitive neuroscience, neuroimaging of aging, and emotions. Please spread the word, and if interested, reach out. I will be in person at #CNS2023 and at #AffectScience2023
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I am looking to submit a Diversity Supplement to @NIHAging to hire a coordinator to work on cognitive neuroscience, neuroimaging of aging, and emotions. Please spread the word, and if interested, reach out. I will be in person at #CNS2023 and at #AffectScience2023
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Lorenzo Pasquini, PhD retweeted
Adit Friedberg@AditFriedberg27 Feb 2023
Why do some patients with #FTD unexpectedly become visually artistic? What can this teach us about neural mechanisms underlying human creativity? Check out our new @JAMANeuro paper bit.ly/FTDCreativity @brucemillerucsf @UCSFmac @GBHI_Fellows #creativity 🧠🎨🧵
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What is the link between brain gradients and nodal degree? Some hints from our paper looking at gradient dispersion in major depression disorder doi.org/10.1016/j.bpsc.2022.…
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Emergence of visual artistic creativity in frontotemporal dementia. bit.ly/3jio3Ne @AditFriedberg @lollo_pasquini @jesseaaronbrown @Rankin_Lab @DataCooker @relajoie @mundada_nidhi @YokoyamaLabUCSF @Zachary94010852 @RabLab_UCSF @AlbaLanguage @brucemillerucsf
Alzheimer's & Dementia journal

ALT Alzheimer's & Dementia journal

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