Building a community of people and research to understand and engineer better mindware—both human and AI. 501(c)3 NFP. See also: @RADVACproject
Boston, MA
Joined May 2013
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Mind First retweeted
Everyone is arguing about global-scale AI risks, but many remain poorly informed about key published ideas and risk factors. Here is my intro for newbies to old hands, doomers to zoomers. prestonestep.substack.com/p/…
Mind First retweeted
I'm really happy with how my "Longevity Lightning Talks" event went on October 9th. We had five speakers: @PrestonWEstep, myself, @GStolyarovII, @IanHuyett, and Nolan Shafik.
Three talks were recorded and are now published:
Preston Estep :
youtube.com/watch?v=9-bRs-HN…
Dan Elton:
youtube.com/watch?v=4Eq3BRfJ…
Gennady Stolyarov II:
youtube.com/watch?v=Ud7rp3PA…
There was a lot of excitement and energy in the room after the event, and afterwards a group of about 10 of us walked to the new Atlas Hotel near HBS and continued discussions at the rooftop bar and terrace late into the night.
Thank you to @JustinQTaylor for making it part of Boston Longevity Week!
The event was sponsored by @MetascienceObs and @mind_first.
I'll be running similar events in Cambridge/Somerville in the future. Topics of interest include metascience, longevity science, longevity biotechnology, AI for science, AI alignment, and the AI "deccel vs accel" debate. To be notified of future events, sign up to this email list here: metascienceobservatoryboston… and follow this page on Luma: luma.com/metascienceobservat…
Mind First retweeted
Everyone should read this highly detailed blog post on “How to pandemic-proof the world.” I don’t share their optimism that such a goal is achievable, but it is an important goal.
I've been thinking hard about modern biosecurity for five years.
In the course of that thinking, I've learned a lot about what the field consensus is on a complete biodefense stack for the AI age.
Today, as part of my work with @BlueDotImpact, @chrisstrahle_ and I have published an overview of this defense stack, alongside a starting list of ten projects we would like to support motivated founders to build.
Funding will be available through the Seed Grants program.
Please share this with the best founders you know.
blog.bluedot.org/p/biosecuri…
Mind First retweeted
Respiratory illness/flu season is fast approaching. If you hate to be sick and you haven’t read my posts Modernizing Variolation Part 1 prestonestep.substack.com/p/… and Part 2 prestonestep.substack.com/p/…, you really should. Modernized Variolation methods are easy and I have used them to avoid four consecutive respiratory illnesses in my home.
xitter.cf/PrestonWEstep/status/2…
Check out my Substack post: Modernizing Variolation, Part 2. A case report on the second consecutive time I avoided getting ill by using MV when all others living in my home were sick with a respiratory illness. prestonestep.substack.com/p/… If your kids are back in school you need to read this!
Mind First retweeted
Definitely! Communities should standardize practices and build infrastructure around Modernized Variolation. Disease transmission would be greatly reduced. I'm not opposed to vaccination but MV is a powerful and completely unused approach to staying healthy.
Mind First retweeted
PSA for Boston-area folks and anyone visiting Boston Longevity Week events!
I'm organizing a lightning talks event for the evening of October 9th. The venue is in Cambridge, about a 15 minute walk from where the Translational Longevity Summit will take place! (link to RSVP 👇)
Mind First retweeted
2.5 million kids.
No evidence of vaccines contributing to autism risk.
At some point, antivaxers are going to have to put the crack pipe down and wake up...
ovid.com/jnls/pidj/abstract/…
Mind First retweeted
Certain aspects of biowarfare are deeply asymmetric
Thanks @WSJ
Red Queen Bio is using artificial intelligence to design antibody drugs for novel pathogens—before future AI systems create them. on.wsj.com/4yiMTy1
Mind First retweeted
The event is sponsored by the @Mind_First Foundation and the @MetascienceObs and taking place as part of bostonlongevityweek.com
Legal expert @IanHuyett will also be traveling from NH to give a talk about Right to Try laws and FDA policy!
RSVP here => luma.com/gpz4wljv
Mind First retweeted
2027 is going to be the inflection point for AI
ppl will argue that AGI arrived earlier, but 2027 could be the year we get end-to-end recursive self-improvement, with AGI rapidly pushing us toward superintelligence
and once those self-improvement loops kick in, accelerating returns and the intelligence explosion will be impossible to ignore
Mind First retweeted
RSVP here: luma.com/gpz4wljv
This event is taking place as part of bostonlongevityweek.com
Confirmed speakers so far include @PrestonWEstep , @GStolyarovII, and @IanHuyett
RT @PrestonWEstep: Check out my Substack post: Modernizing Variolation, Part 2. A case report on the second consecutive time I avoided gett…
Mind First retweeted
This debate should happen @sapinker and @slatestarcodex
I think you've done enough calling us paranoid and preposterous. The next step is for you to defend your position in public against someone who will push back against it. I'm happy to meet you for a debate anywhere, anytime.
You're a world-famous veteran of dozens of debates against the world's top intellectuals, and I've never argued in public before, so adjusting for the relative correctness of our positions, if you're a betting man I'm happy to put my $5000 against your $1000 (ie 5:1 odds in your favor) that I'll win by some standard of audience opinion change. Let me know if you're interested and we can hash out details.
Mind First retweeted
Absolutely correct! See my recent publication describing this exact dynamic: frontiersin.org/journals/psy…
Mind First retweeted
It has been almost a week since this post. I'm less afraid of AI and more afraid than ever of the humans who will misunderstand the situation, fight with each other over the wrong things, and screw up the incredible potential for good. Why? Because that's already happening.
Mind First retweeted
True, they are gambling with our lives. But they are far from alone and the odds and outcomes are incredibly uncertain. If they pause, others (including bad actors) will fill the void. Natural selection ensured that competition is the natural state of humanity. There is no stopping. You need to consider a more realistic and constructive solution.
Mind First retweeted
As many of you know, the RaDVaC core team has been working both on articulating the biosecurity risks imposed by AI, and on AI's potential to increase biosecurity (tools weighted in a biosecurity-positive direction, rather than those capable of dual use and asymm. high risk).
Mind First retweeted
PSA for Boston-area folks: on June 13 there will be a debate/discussion at Microsoft NERD about the future of humanity + AI, hosted by @Mind_First: eventbrite.com/e/ai-successi…
Feat. @DanFaggella, @PrestonWEstep, and @BrianMDelaney. Dinner and non-alcoholic beverages will be served.
