Johns Hopkins Univ., NASA, ESA, DFVLR.
Internet From Thailand
Joined January 2014
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Richard Kollen retweeted
Putin's diesel arrives in New York Nov 7 aboard the Agioi Fanendes: 40,000 tons, the first Russian fuel cargo since 2022. It's coming in on a Treasury license that sidesteps federal law. New York should refuse to be the loading dock for Putin's war chest. 🧵 1/5
EXCLUSIVE: Tanker carrying 40,000 T of Russian diesel heads to New York after Putin-Trump deal, data shows reut.rs/47zYFZ2 reut.rs/47zYFZ2
Richard Kollen retweeted
Doctoral Student Position in Immunometabolism for Alphavirus Therapeutics 2026 in Sweden
Host: Karolinska Institutet
Host Country: Sweden
Category: PhD Position in Medical Research
Eligible: International applicants who meet the eligibility requirements, including Nigerian students
Reward: Paid doctoral studentship with a contractual salary for up to 4 years of full-time study. Employees also receive free gym access and reimbursement for medical care.
Deadline: 30 October 2026
Eligibility:
- Must hold a master's degree or meet the equivalent doctoral education entry requirements.
- Must demonstrate English proficiency equivalent to English B/English 6 in Sweden, with excellent communication skills (minimum C1/C2 CEFR level).
- Must not hold a doctoral degree at the time of employment.
- Must meet the MSCA Doctoral Network mobility rule: must not have resided or carried out their main activity in Sweden for more than 12 months in the 36 months immediately before employment.
- Should have a strong interest in virus-host interactions, molecular virology, immunology and cell biology.
- Experience in cell culture, organoids, virology, molecular biology, microscopy, omics technologies or R programming is advantageous.
Required documents: Personal letter, CV, degree projects and previous publications (if any), documents proving general and specific eligibility, and evidence of relevant skills and experience.
Apply: kidoktorand.varbi.com/en/wha…
Note: You must apply through both the MERIT website and Karolinska Institutet's application system for your application to be considered complete.
Richard Kollen retweeted
Nanyang President's Graduate Scholarship (NPGS) 2027-2028 for PhD in Singapore
Host: Nanyang Technological University (NTU)
Host Country: Singapore
Category: PhD Scholarship
Eligible: Applicants of All Nationalities (preference is given to Singapore citizens and permanent residents)
Reward: Fully funded; no conditions or bond. Monthly stipend for international students: STEM S$6,300 (CIS) or S$4,600 (non-CIS); social sciences and humanities S$4,000. Plus conference allowance up to S$4,000 a year, S$500 books a year, one-time S$1,500 for IT, and a one-time S$600 thesis allowance in the final year
Deadline: 30 December 2026 (applications open 1 November 2026)
Duration: Valid for one year, extendable on satisfactory progress, up to a maximum of four years for PhD
Intake: August to January
Eligibility:
- Open to applicants worldwide with a Bachelors degree with Honours (Highest Distinction) or equivalent
- Final-year students may apply with university documentation showing they will soon receive an Honours (Highest Distinction) degree or equivalent
- Valid TOEFL, IELTS, GRE, GMAT or GATE scores required
Required documents: passport or ID, one recent colour passport photograph, test scores, degree certification and official transcripts, two academic referee reports, plus a research proposal, resume and publications where applicable
How to apply: The application is entirely online and free of charge. National Institute of Education (NIE) applicants apply directly through NIE's website by the same deadline
Apply: ntu.edu.sg/admissions/gradua…
I sincerely hope that this Nobel Prize-winning knowledge can help with the horrible Multiple Sclerosis Disease which affects many millions worldwide.
MS is when the myelin in the CNS of MS Patients is attacked by the patient’s own immune system.
Comments?
*The Nobel Prize-winning discovery that could change how we fight disease*
What stops your immune system from turning against your own body? The answer lies in a tiny group of cells acting like peacekeepers inside you.
The 2025 Nobel Prize in Physiology or Medicine was awarded to Shimon Sakaguchi, Mary E. Brunkow, and Fred Ramsdell for discoveries explaining how the immune system prevents itself from attacking healthy tissues.
Their research revealed the importance of **regulatory T cells (Tregs)** and a master gene called **FOXP3**, which helps these cells develop and function. Think of them as security guards that stop your body's defense system from attacking the wrong targets.
But here's where it gets even more fascinating. When this control system fails, the immune system can attack healthy organs, contributing to serious autoimmune diseases.
Scientists are now exploring how to use this knowledge to develop treatments that restore immune balance—or carefully adjust immune responses to help fight cancer.
Could learning to control our immune system's own brakes unlock new ways to treat some of humanity's most challenging diseases? The research offers exciting possibilities, but many potential treatments are still being investigated.
Source (APA):
Nobel Assembly at Karolinska Institutet. (2025). *The Nobel Prize in Physiology or Medicine 2025
ALT The Nobel Prize-winning discovery that could change how we fight disease What stops your immune system from turning against your own body? The answer lies in a tiny group of cells acting like peacekeepers inside you. The 2025 Nobel Prize in Physiology or Medicine was awarded to Shimon Sakaguchi, Mary E. Brunkow, and Fred Ramsdell for discoveries explaining how the immune system prevents itself from attacking healthy tissues. Their research revealed the importance of **regulatory T cells (Tregs)** and a master gene called **FOXP3**, which helps these cells develop and function. Think of them as security guards that stop your body's defense system from attacking the wrong targets. But here's where it gets even more fascinating. When this control system fails, the immune system can attack healthy organs, contributing to serious autoimmune diseases.
Richard Kollen retweeted
Today, we’re announcing an open call for guest investigators in life sciences. Over 8–12 weeks, guest investigators will work directly with my team and other Anthropic researchers to produce analyses and tools for their work. We’ll run our models and harnesses, at no cost to them. We’ll work together to open-source the resulting data, artifacts, and code, and write preprints about what we find.
We want humans to remain at the center of scientific discovery, deciding what questions to pursue, and how to pursue them. Those decisions are not ours to make alone. This open call is part of our ongoing efforts at Anthropic to support researchers and accelerate scientific discovery.
I’m looking for principal investigators and their research groups at academic institutions, nonprofits, or government labs, working in causal human biology, structural and computational molecular biology, medicinal chemistry, drug discovery, and clinical science.
Applications are open for about 14 days: anthropic.com/news/open-call…
OMG, these new pressure discoveries are blowing my mind.
Squeezing cells and now pressure on shin bones?
Mechanical pressure on shin bones extended mouse lifespan by 80 days (+9.4%).
That’s the human equivalent of 7–9 yrs.
Bone pressure triggers PIEZO1 sensors to broadcast anti-aging signals to the brain, liver, and immune system.
If this translates to humans, my dunk training is flooding my entire body with anti-aging juice.
Richard Kollen retweeted
⚡ PhD Student in Laser-Induced Plasmas of Functional Oxides – Paul Scherrer Institute (PSI)
🇨🇠Villigen, Switzerland
Department: Materials Science and Nanotechnology
Supervisor: Dr. Nikita Shepelin
Deadline: November 22, 2026
Degree: Enrolled in the ETH ZĂĽrich doctoral program
đź“‹ About the Project
Study how pulsed laser deposition parameters shape the composition and function of complex oxide thin films for ferroelectric field effect transistors. You will run a deposition chamber with unique in situ characterization and use machine learning to make film growth more reproducible.
🔬 Ideal Candidate
• Master's in materials science, chemistry, physics or a related field
• Foundational knowledge of laser-induced plasmas
• Vacuum, physical vapor deposition and Python skills are a plus
• Professional English; German is an asset
✨ Why Apply
Work in an international collaboration at Switzerland's largest research institute, with a PhD title from ETH ZĂĽrich.
🔗 More Info: phdscanner.com/opportunities…
#PhD #PhDPosition #PSI #Switzerland #MaterialsScience #ThinFilms #MachineLearning #AcademicJobs
Richard Kollen retweeted
Never thought to squeeze a cell
Squeezing a fibroblast nucleus for a moment opens chromatin at mappable loci. Yang Song and Song Li at UCLA aimed CRISPRa guides at exactly those spots. Fibroblast to neuron conversion went from under 3% to about 40%, with no virus. In aged mouse fibroblasts, the same mechanically enhanced Oct4 activation lowered DNA methylation age on the mouse skin clock, close to the level of cells from young animals. But global methylation also drops. so how much of this is rejuvenation rather than dilution is the open question. Title: Mechano-epigenetic enhancement of CRISPR activation of target genes fo… sciencedirect.com/science/ar…
Richard Kollen retweeted
Donald Trump is already preparing for a possible Democratic victory in the midterm elections and has explained what he intends to do if Democrats win.
His plan is remarkably simple: “If there’s political gridlock, I’ll veto everything. And the Democrats would come to negotiate.”
In other words, even if Democrats take control of Congress, Trump expects to turn divided government into a tool of pressure: blocking their legislation with presidential vetoes until they agree to negotiate on his terms.
But there’s one important detail.
If Democrats win the House of Representatives, they will be able to block Trump’s legislative agenda, exercise control over federal spending, summon administration officials to hearings, and investigate his administration. Presidential vetoes cannot stop congressional oversight or investigations.
And if Democrats also win the Senate, they will gain additional power to delay or block judicial nominations and appointments of senior government officials.
So the reality might look very different from Trump’s vision of “I veto everything, and they come begging for a deal.”
Instead, America could face years of legislative deadlock, budget battles, and congressional investigations.
Trump, however, is already presenting the possibility of political paralysis as another negotiating advantage.
If he cannot govern the country on his own terms, he can always try to hold it hostage instead.
That's pretty much the idea.
Richard Kollen retweeted
I looked into Theranos 2.0 more. Aside from it being Theranos 2.0, it is a lot of investor buzzwords or concepts put together / it doesn’t make sense from a clinical or business perspective.
This is assuming their instrument and assays work (no evidence of this)
Haemanthus has said it’s going after dogs / veterinary and has framed itself around early detection of conditions researchers have studied with Raman (cancers, Parkinson’s, ALS markers, COVID).
Biggest problem these are 1 time tests for diagnosis. So there is no business.
And for diagnosis of these serious conditions, you would want to err on a bigger sample to be sure of the diagnosis (which is to avoid Poisson sampling error distribution; see, comes up all the time.)
Example: You could have a positive biomarker in 5 mL of blood, but if you only take 50 microliters, then you have a high chance of getting zero (neg disease as a test result) just b/c you had a tiny fraction of the sample that missed it.
Ok well, COVID you can test more frequently, No reason to sell a Raman COVID test with all other simpler / cheaper options.
They said they’re going after dogs / vetinerady obviously saying it b/c there is less regulatory for animals than humans. Sounds good to Investors.
Dogs do not get Parkinson’s or ALS like humans. Do we test dogs for COVID all the time?
The economics aren’t there either for high frequency tests like CBC, CMP. There are other technologies for miniscule volume tests which are more scalable and then overall cheaper.
It doesn’t make sense and this was analyzing it in the best light of assuming the tech all works. In Theranos 1.0, the tech didn’t even work as we know.
Another crazy one…
share.google/GLuTGkbijJMfdSq…
One Conman started an unessary War with IRAN. Now everyone on Planet Earth must dig deeper into their pockets to afford gas or diesel. One man!
Source:%20The%20New%20York%20Times share.google/r7aHN0OVWPkQfK4…
Richard Kollen retweeted
facebook.com/share/r/1HiE6pS…
đź«€ Left Coronary Artery (LCA): Know the Branches!
The Left Main (LM) divides into the LAD and LCX. The LAD gives diagonal and septal perforator branches, while the LCX gives obtuse marginal branches.
#Cardiology #LCA #CoronaryAnatomy #LAD #LCX
Richard Kollen retweeted
9 in 10 drugs fail in trials. Most fail because the target was wrong.
At Gero we built and now open sourced a tool to score any target list against the only ground truth there is: clinical trial outcomes. Paper out in Bioinformatics (see the refs below, the code is open).
A few things we found:
– The famous “genetic support = 2.6x more likely to reach approval” reproduces, with open data, no Citeline needed.
– More clinical data makes the benchmark worse. Pool every open registry and 2.6x collapses to 1.5x. Curated beats aggregated.
We use this on our own models. Use it on yours. pip install ct-validation
More info on my substack peterfedichev.substack.com/p….
– this is a bit more reliable way to get updates like this.
As usual, please follow, like and repost - more interesting stuff to come.
Corny!
Honored to be elected a Full Member of Sigma Xi, The Scientific Research Honor Society, home to more than 200 Nobel Prizes throughout its history.
My deepest gratitude to my mentors for their guidance, trust, and continued inspiration.
#SigmaXi #Neuroscience #Neurosurgery
Richard Kollen retweeted
BREAKING: Trump has just preemptively filed a lawsuit seeking to block certification of Alaska's US Senate election if the Republican incumbent Sen. Dan Sullivan loses.
It’s happening folks! Trump is once again trying to overturn the results of an election before it even takes place.
Richard Kollen retweeted
Egyptian neurosurgeon Dr. Ali Salah performing awake functional brain surgery on a patient with severe tremor lasting over 10 years, showing immediate symptom resolution during the procedure.
Richard Kollen retweeted
🌏🌊🇦🇪🇸🇳 Who’s going to the 2026 UN Water Conference in Abu Dhabi (8–10 December)?
🤝 I’d love to connect with others working on water quality, monitoring innovation, SDG 6 implementation, or scalable solutions for contaminants, including microplastics and nanoplastics.
📲🌊⚠️🦠We’re also working on other AI smartphone field assays also on like bacteria (E. Coli) and Legionella as well as surrogates for algal bloom.
Happy to meet in person or virtually beforehand. Drop a comment or DM if you’ll be there.
